mb Search Results


mda mb 231 cells  (ATCC)
99
ATCC mda mb 231 cells
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Mda Mb 231 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mda mb 231 cells/product/ATCC
Average 99 stars, based on 1 article reviews
mda mb 231 cells - by Bioz Stars, 2026-05
99/100 stars
  Buy from Supplier
cell lines mda mb 231 atcc  (ATCC)
99
ATCC cell lines mda mb 231 atcc
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Cell Lines Mda Mb 231 Atcc, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cell lines mda mb 231 atcc/product/ATCC
Average 99 stars, based on 1 article reviews
cell lines mda mb 231 atcc - by Bioz Stars, 2026-05
99/100 stars
  Buy from Supplier
tgf β1  (R&D Systems)
97
R&D Systems tgf β1
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Tgf β1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/tgf β1/product/R&D Systems
Average 97 stars, based on 1 article reviews
tgf β1 - by Bioz Stars, 2026-05
97/100 stars
  Buy from Supplier
recombinant mouse ifn b  (R&D Systems)
95
R&D Systems recombinant mouse ifn b
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Recombinant Mouse Ifn B, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant mouse ifn b/product/R&D Systems
Average 95 stars, based on 1 article reviews
recombinant mouse ifn b - by Bioz Stars, 2026-05
95/100 stars
  Buy from Supplier
anti mouse pd 1 mab  (Bio X Cell)
94
Bio X Cell anti mouse pd 1 mab
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Anti Mouse Pd 1 Mab, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti mouse pd 1 mab/product/Bio X Cell
Average 94 stars, based on 1 article reviews
anti mouse pd 1 mab - by Bioz Stars, 2026-05
94/100 stars
  Buy from Supplier
human tgf β1  (R&D Systems)
96
R&D Systems human tgf β1
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Human Tgf β1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human tgf β1/product/R&D Systems
Average 96 stars, based on 1 article reviews
human tgf β1 - by Bioz Stars, 2026-05
96/100 stars
  Buy from Supplier
serum ck mb concentration  (Novus Biologicals)
94
Novus Biologicals serum ck mb concentration
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Serum Ck Mb Concentration, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/serum ck mb concentration/product/Novus Biologicals
Average 94 stars, based on 1 article reviews
serum ck mb concentration - by Bioz Stars, 2026-05
94/100 stars
  Buy from Supplier
collagenase solution  (Rockland Immunochemicals)
94
Rockland Immunochemicals collagenase solution
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Collagenase Solution, supplied by Rockland Immunochemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/collagenase solution/product/Rockland Immunochemicals
Average 94 stars, based on 1 article reviews
collagenase solution - by Bioz Stars, 2026-05
94/100 stars
  Buy from Supplier
sodium dodecyl sulfate sds  (Rockland Immunochemicals)
93
Rockland Immunochemicals sodium dodecyl sulfate sds
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Sodium Dodecyl Sulfate Sds, supplied by Rockland Immunochemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/sodium dodecyl sulfate sds/product/Rockland Immunochemicals
Average 93 stars, based on 1 article reviews
sodium dodecyl sulfate sds - by Bioz Stars, 2026-05
93/100 stars
  Buy from Supplier
tbs t  (Rockland Immunochemicals)
95
Rockland Immunochemicals tbs t
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Tbs T, supplied by Rockland Immunochemicals, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/tbs t/product/Rockland Immunochemicals
Average 95 stars, based on 1 article reviews
tbs t - by Bioz Stars, 2026-05
95/100 stars
  Buy from Supplier
western blot  (Rockland Immunochemicals)
96
Rockland Immunochemicals western blot
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Western Blot, supplied by Rockland Immunochemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/western blot/product/Rockland Immunochemicals
Average 96 stars, based on 1 article reviews
western blot - by Bioz Stars, 2026-05
96/100 stars
  Buy from Supplier
tris hcl  (Rockland Immunochemicals)
90
Rockland Immunochemicals tris hcl
A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A <t>)</t> <t>or</t> <t>MDA-MB-231</t> ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].
Tris Hcl, supplied by Rockland Immunochemicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/tris hcl/product/Rockland Immunochemicals
Average 90 stars, based on 1 article reviews
tris hcl - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier

Image Search Results


A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A ) or MDA-MB-231 ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].

Journal: Oncogene

Article Title: X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer

doi: 10.1038/s41388-026-03740-w

Figure Lengend Snippet: A , B Xenograft assays showing subcutaneous tumor growth of MCF-7 ( A ) or MDA-MB-231 ( B ) breast cancer cells ectopically expressing dox-inducible FLAG-GFP or XCP-FLAG ( left ). Tumor weight at end of experiment is shown ( right ). Animals injected with MCF-7 cells had E2-pellet implantations at the back of the neck to promote growth of MCF-7 cells in vivo. All animals were fed doxycycline in their chow. Each point represents the mean ± SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. Significance was calculated using unpaired t-test. C , D Expression of FLAG-GFP or XCP-FLAG in tumor tissue was validated from MCF-7 ( C ) or MDA-MB-231 ( D ) xenograft tumors by Western blot ( left ) and RT-qPCR ( right ). For Western blot, 3 representative tumors from each group are shown. β-tubulin was used as a loading control. For RT-qPCR, the average of all tumors from each group is shown. RNA levels were quantified by normalizing to housekeeping gene RPL19 mRNA. Each bar represents the mean + SEM. For MCF-7, GFP n = 7 and XCP n = 7; For MDA-MB-231, GFP n = 8 and XCP n = 8. [See also Fig. ].

Article Snippet: MCF-7 (ATCC; RRD:CVCL_0031) cells were kindly provided by Benita S. Katzenellenbogen (University of Illinois, Urbana-Champaign, Champaign, IL) and MDA-MB-231 cells were purchased from the American Type Culture Collection (ATCC; RRID:CVCL_0062).

Techniques: Expressing, Injection, In Vivo, Western Blot, Quantitative RT-PCR, Control

A , B Heatmaps ( left ) and Gene Ontology analysis ( right ) showing XCP-mediated gene expression changes in MCF-7 ( A ) and MDA-MB-231 ( B ) xenograft tumors. C , D Box plots showing gene set analysis of XCP-induced genes and their expression levels stratified into breast cancer subtypes using PAM50 gene set analysis ( left ) and stratified by ER status ( right ) in MCF-7 ( C ) and MDA-MB-231 ( D ) xenograft tumors. Observed differences are significant as determined by an ANOVA comparison of the means ( P value < 0.00001). [See also Fig. ].

Journal: Oncogene

Article Title: X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer

doi: 10.1038/s41388-026-03740-w

Figure Lengend Snippet: A , B Heatmaps ( left ) and Gene Ontology analysis ( right ) showing XCP-mediated gene expression changes in MCF-7 ( A ) and MDA-MB-231 ( B ) xenograft tumors. C , D Box plots showing gene set analysis of XCP-induced genes and their expression levels stratified into breast cancer subtypes using PAM50 gene set analysis ( left ) and stratified by ER status ( right ) in MCF-7 ( C ) and MDA-MB-231 ( D ) xenograft tumors. Observed differences are significant as determined by an ANOVA comparison of the means ( P value < 0.00001). [See also Fig. ].

Article Snippet: MCF-7 (ATCC; RRD:CVCL_0031) cells were kindly provided by Benita S. Katzenellenbogen (University of Illinois, Urbana-Champaign, Champaign, IL) and MDA-MB-231 cells were purchased from the American Type Culture Collection (ATCC; RRID:CVCL_0062).

Techniques: Gene Expression, Expressing, Comparison