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Image Search Results
41 ]. *t-test ICR1 MassARRAY vs. ICR1 pyrosequencing: P = 0.2302. § t-test ICR2 MassARRAY vs. ICR2 pyrosequencing: P = 0.4391. " width="100%" height="100%">
Journal: Epigenetics
Article Title: Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders
doi: 10.1080/15592294.2018.1514230
Figure Lengend Snippet: Methylation analyses of 12 imprinted iDMRs by MassARRAY in patients with BWS and SRS with known epimutations at ICR1 or ICR2. Cases with MLID are underlined. Aberrant methylation was defined as methylation values deviating +/- two standard deviations from the mean value observed in amniotic fluid (AF) or blood control samples. Different shades of yellow indicate 5% intervals of LOM (with light yellow corresponding to slight LOM and dark yellow corresponding to heavy LOM), while different shades of blue represent 5% intervals of GOM (from light blue corresponding to slight GOM to dark blue indicating heavy GOM). The last two columns contain ICR1/ICR2 methylation values determined by pyrosequencing, according to protocols previously described [
Article Snippet: Methylation profile of 12 iDMRs frequently involved in MLID in BWS/SRS [ , , , ] was investigated by the
Techniques: Methylation, Control