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Image Search Results
Journal: International Journal of Neuropsychopharmacology
Article Title: Ketanserin Reverses the Acute Response to LSD in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Participants
doi: 10.1093/ijnp/pyac075
Figure Lengend Snippet: Acute subjective effects of lysergic acid diethylamide (LSD) over time on visual analog scales (VASs). Ketanserin reversed LSD-induced subjective effects compared with placebo. LSD was administered at t = 0 hours. Ketanserin or placebo was administered at t = 1 hour. The data are expressed as the mean ± SEM in 24 participants (12 men, 12 women). Additional subjective effects are shown in supplementary Figure 1. The corresponding maximal effect and area under the effect curve (AUEC) values and statistics are shown in .
Article Snippet: LSD (D-lysergic acid diethylamide freebase, high-performance liquid chromatography purity >99%;
Techniques:
Journal: International Journal of Neuropsychopharmacology
Article Title: Ketanserin Reverses the Acute Response to LSD in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Participants
doi: 10.1093/ijnp/pyac075
Figure Lengend Snippet: Lysergic acid diethylamide (LSD) effects on 5 Dimensions of Altered States of Consciousness (5D-ASC) scale. Ketanserin administration 1 hour after LSD significantly reduced LSD-typical alterations of mind compared with placebo, indicated mainly by significantly lower three dimension (3D-OAV) and five dimension (5D-ASC) total scores. Abbreviations: AA, auditory alterations; AED, anxious ego-dissolution; OB, oceanic boundlessness; VIR, vigilance reduction; VR, visionary restructuralization. The data are expressed as the mean ± SEM percentage of maximally possible scale scores in 24 participants (12 men, 12 women). * P < .05, ** P < .01, *** P < .001, significant difference between ketanserin and placebo. Full statistics are shown in .
Article Snippet: LSD (D-lysergic acid diethylamide freebase, high-performance liquid chromatography purity >99%;
Techniques: Dissolution
Journal: International Journal of Neuropsychopharmacology
Article Title: Ketanserin Reverses the Acute Response to LSD in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Participants
doi: 10.1093/ijnp/pyac075
Figure Lengend Snippet: Pharmacokinetics of lysergic acid diethylamide (LSD) and ketanserin. Ketanserin had no effect on the pharmacokinetics of LSD compared with placebo. The data are expressed as the mean ± SEM in 24 participants (12 men, 12 women). LSD was administered at t = 0 hours. Ketanserin or placebo was administered at t = 1 hour. The corresponding pharmacokinetic parameters are listed in .
Article Snippet: LSD (D-lysergic acid diethylamide freebase, high-performance liquid chromatography purity >99%;
Techniques: