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Image Search Results
Journal: Journal of Clinical Laboratory Analysis
Article Title: Super‐enhancer–associated long noncoding RNA RP11‐569A11.1 inhibited cell progression and metastasis by regulating IFIT2 in colorectal cancer
doi: 10.1002/jcla.23780
Figure Lengend Snippet: SE‐LncRNA microarray analysis of CRC tissues. A, The scatter plot displayed variation in SE‐LncRNA expression between group‐N (normal) and group‐T (CRC). B, The volcano plot represented the fold change values and P‐values of the microarray data. C, Hierarchical clustering revealed differentially expressed SE‐LncRNAs (fold change >2, p ‐value <0.05). Red and green colors represented upregulated and downregulated SE‐LncRNAs, respectively
Article Snippet: Given that the expression abundance of SE‐LncRNA at lower levels than that of mRNA, and RNA‐seq is not sensitive to low‐abundance SE‐LncRNAs, we conducted
Techniques: Microarray, Expressing
Journal: Frontiers in Cell and Developmental Biology
Article Title: Down-Regulation of Lnc-CYP7A1-1 Rejuvenates Aged Human Mesenchymal Stem Cells to Improve Their Efficacy for Heart Repair Through SYNE1
doi: 10.3389/fcell.2020.600304
Figure Lengend Snippet: Expression profile of lncRNAs in young and old hBM-MSCs. (A) lncRNA expression in old (O) and young (Y) hBM-MSCs was determined by microarray analysis. (B) Differential lncRNA expression was validated by real-time qPCR. n = 5/group; ∗ P < 0.05 O vs. Y.
Article Snippet: Total RNA was isolated from hBM-MSCs after cultured in hypoxic conditions for 72 h. 12 ×
Techniques: Expressing, Microarray
Journal: Frontiers in Cell and Developmental Biology
Article Title: Down-Regulation of Lnc-CYP7A1-1 Rejuvenates Aged Human Mesenchymal Stem Cells to Improve Their Efficacy for Heart Repair Through SYNE1
doi: 10.3389/fcell.2020.600304
Figure Lengend Snippet: The expression of SYNE1 was inhibited by lnc-CYP7A1-1. (A) Gene co-expression networks were built to detect the interactions among lncRNAs and genes. Red color indicates expression up-regulated and green color indicates expression down-regulated. The dots represents genes and the diamond represents lncRNAs. (B) The expression of SYNE1 in old (O) and young (Y) hBM-MSCs was determined by microarray analysis. (C) The expression of SYNE1 in Old (O) and young (Y) hBM-MSCs was compared by real-time qPCR. (D) Old (O) hBM-MSCs were transfected by inhibition lentivirus (O-sh-CYP7A1) or control lentivirus (O-c), respectively. The expression of SYNE1 was compared by real-time qPCR. n = 5/group; * P < 0.05 O vs. Y, O-c vs. O-sh-CYP7A1.
Article Snippet: Total RNA was isolated from hBM-MSCs after cultured in hypoxic conditions for 72 h. 12 ×
Techniques: Expressing, Microarray, Transfection, Inhibition, Control