Journal: Oncology Letters

Article Title: Fatty acids inhibit anticancer effects of 5-fluorouracil in mouse cancer cell lines

doi: 10.3892/ol.2017.6190

Figure Lengend Snippet: Effect of LA or EA on 5-FU-induced reduction of cancer cell viability. CT26 cells were treated with (A) LA (50 µg/ml) or (B) EA (20 µg/ml), administered concurrently with 5-FU (1 µg/ml). LL2 cells were treated with (C) LA (50 µg/ml) or (D) EA (20 µg/ml), administered concurrently with 5-FU (1 µg/ml). CMT93 cells were treated with (E) LA (50 µg/ml) or (F) EA (20 µg/ml), administered concurrently with 5-FU (1 µg/ml). (G) LA (50 µg/ml) (H) or EA (20 µg/ml) was administered 24 h prior to 5-FU treatment (1 µg/ml) in 3 cancer cell lines. Data are expressed as the mean ± standard deviation. LA, linoleic acid; EA, elaidic acid; 5-FU, 5-fluorouracil; Mock, vehicle treated with 70% ethanol.

Article Snippet: The mouse rectal carcinoma CMT93 cell line and the mouse lung cancer LL2 cell line were purchased from DS Pharma Biomedical Co., Ltd. (Osaka, Japan).

Techniques: Standard Deviation

Journal: Cancer Immunology, Immunotherapy : CII

Article Title: Optimized magnitude of cryosurgery facilitating anti-tumor immunoreaction in a mouse model of Lewis lung cancer

doi: 10.1007/s00262-016-1858-x

Figure Lengend Snippet: a Tumor volume analysis using LL2 cells. Changes of tumor volume of the abscopal tumor. Tumor volume was measured every 2 days. *p < 0.05 between the indicated groups. b Kaplan–Meier plot to show the survival after treatment of the mice in each group. Statistical differences were tested using log-rank test

Article Snippet: Lewis lung carcinoma (LL2) cells and B16 melanoma cells were obtained from DS Pharma Biomedical Corporation (Tokyo, Japan), cultured in DMEM medium supplemented with 15 % fetal bovine serum, and incubated in the specified pathogen-free conditions with 5 % CO 2 at 37 °C.

Techniques: