Journal: Journal of Agricultural and Food Chemistry

Article Title: Dietary Inhibitors of CYP3A4 Are Revealed Using Virtual Screening by Using a New Deep-Learning Classifier

doi: 10.1021/acs.jafc.2c00237

Figure Lengend Snippet: Foods containing compounds predicted by FooDB to inhibit CYP3A4. (A) Analysis by food groups. The proportion of compounds related to the group in the total number of compounds is shown. Some compounds were assigned to more than one group. (B) Top 10 foods containing CYP3A4 inhibitors.

Article Snippet: The pCW-LIC plasmid (#26098) for CYP3A4 cloning was purchased from Addgene (MA, USA).

Techniques:

Journal: Journal of Agricultural and Food Chemistry

Article Title: Dietary Inhibitors of CYP3A4 Are Revealed Using Virtual Screening by Using a New Deep-Learning Classifier

doi: 10.1021/acs.jafc.2c00237

Figure Lengend Snippet: CYP3A4 inhibition by representative compounds. (A) Chemical structures. (B) Results are expressed as the mean ± SE of the values from three independent experiments. IC 50 values were calculated using nonlinear regression ( R 2 = 0.913 for bilobetin and R 2 = 0.903 for PPP).

Article Snippet: The pCW-LIC plasmid (#26098) for CYP3A4 cloning was purchased from Addgene (MA, USA).

Techniques: Inhibition

Journal: Journal of Agricultural and Food Chemistry

Article Title: Dietary Inhibitors of CYP3A4 Are Revealed Using Virtual Screening by Using a New Deep-Learning Classifier

doi: 10.1021/acs.jafc.2c00237

Figure Lengend Snippet: Compounds Predicted by the Classifier to Be CYP3A4 Inhibitors

Article Snippet: The pCW-LIC plasmid (#26098) for CYP3A4 cloning was purchased from Addgene (MA, USA).

Techniques: