lepr db Search Results


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MedChemExpress leptin receptor lepr antagonist
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Proteintech lepr
Lepr, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Boster Bio rabbit polyclonal anti lepr antibody
Rabbit Polyclonal Anti Lepr Antibody, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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OriGene lepr expression plasmid
Hypothalamic leptin receptor knockdown attenuates the adipose redistribution-associated with unilateral iWAT injection of Rec2-Cre in male PTEN flox mice. (A) Experimental design. (B) Hypothalamic <t>Lepr</t> <t>expression.</t> (C) iWAT weight at sacrifice. (D) Ratio of Rec2-treated iWAT to the untreated contralateral iWAT. (E) Relative mRNA expression of leptin in iWAT. (F) Ratio of leptin mRNA between Rec2-treated iWAT and untreated contralateral iWAT. Data are means ± SEM. n = 6–7 per group for body weight and tissue weight data. n = 4–6 for qPCR data. *P < 0.05, **P < 0.01, ***P < 0.001.
Lepr Expression Plasmid, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Boster Bio mouse leptin receptor picokine elisa kit
PYY(3 – 36) and Ex4 in combination increases <t>leptin</t> sensitivity and increases the concentration of circulating soluble leptin receptor. A-D) Accumulated food intake (kcal) and body weight change (g) 4h (A, B) and 20h (C, D) after leptin injection(5 mg/kg) at treatment day 10.E) Plasma leptin concentration (pM) at day 15, F: Plasma concentration of soluble leptin receptor (SLR) at day 15, and G: Hepatic Lepra expression at day 15. Data are expressed as means ± SEM, n = 12. Statistical significance was assessed by one-way ANOVA (E) or by two-way ANOVA followed (F and G). In both cases, ANOVA test's were followed Tukey's multiple comparisons test. In case of A-D, test of significance was restricted to comparing within group effects (vehicle and leptin treatment). *p < 0.05, **p < 0.01, and ***p < 0.001.
Mouse Leptin Receptor Picokine Elisa Kit, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Harlan Laboratories bks ++lepr db
PYY(3 – 36) and Ex4 in combination increases <t>leptin</t> sensitivity and increases the concentration of circulating soluble leptin receptor. A-D) Accumulated food intake (kcal) and body weight change (g) 4h (A, B) and 20h (C, D) after leptin injection(5 mg/kg) at treatment day 10.E) Plasma leptin concentration (pM) at day 15, F: Plasma concentration of soluble leptin receptor (SLR) at day 15, and G: Hepatic Lepra expression at day 15. Data are expressed as means ± SEM, n = 12. Statistical significance was assessed by one-way ANOVA (E) or by two-way ANOVA followed (F and G). In both cases, ANOVA test's were followed Tukey's multiple comparisons test. In case of A-D, test of significance was restricted to comparing within group effects (vehicle and leptin treatment). *p < 0.05, **p < 0.01, and ***p < 0.001.
Bks ++Lepr Db, supplied by Harlan Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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clea japan inc non-diabetic lepr db /+ ( db /+) male littermates
PYY(3 – 36) and Ex4 in combination increases <t>leptin</t> sensitivity and increases the concentration of circulating soluble leptin receptor. A-D) Accumulated food intake (kcal) and body weight change (g) 4h (A, B) and 20h (C, D) after leptin injection(5 mg/kg) at treatment day 10.E) Plasma leptin concentration (pM) at day 15, F: Plasma concentration of soluble leptin receptor (SLR) at day 15, and G: Hepatic Lepra expression at day 15. Data are expressed as means ± SEM, n = 12. Statistical significance was assessed by one-way ANOVA (E) or by two-way ANOVA followed (F and G). In both cases, ANOVA test's were followed Tukey's multiple comparisons test. In case of A-D, test of significance was restricted to comparing within group effects (vehicle and leptin treatment). *p < 0.05, **p < 0.01, and ***p < 0.001.
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GemPharmatech Co Ltd leptin receptor (lepr) gene mutant ( db / db ) mice
PYY(3 – 36) and Ex4 in combination increases <t>leptin</t> sensitivity and increases the concentration of circulating soluble leptin receptor. A-D) Accumulated food intake (kcal) and body weight change (g) 4h (A, B) and 20h (C, D) after leptin injection(5 mg/kg) at treatment day 10.E) Plasma leptin concentration (pM) at day 15, F: Plasma concentration of soluble leptin receptor (SLR) at day 15, and G: Hepatic Lepra expression at day 15. Data are expressed as means ± SEM, n = 12. Statistical significance was assessed by one-way ANOVA (E) or by two-way ANOVA followed (F and G). In both cases, ANOVA test's were followed Tukey's multiple comparisons test. In case of A-D, test of significance was restricted to comparing within group effects (vehicle and leptin treatment). *p < 0.05, **p < 0.01, and ***p < 0.001.
Leptin Receptor (Lepr) Gene Mutant ( Db / Db ) Mice, supplied by GemPharmatech Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Harlan UK Ltd bks.cg-+lepr db /+lepr db /olahsd mice
PYY(3 – 36) and Ex4 in combination increases <t>leptin</t> sensitivity and increases the concentration of circulating soluble leptin receptor. A-D) Accumulated food intake (kcal) and body weight change (g) 4h (A, B) and 20h (C, D) after leptin injection(5 mg/kg) at treatment day 10.E) Plasma leptin concentration (pM) at day 15, F: Plasma concentration of soluble leptin receptor (SLR) at day 15, and G: Hepatic Lepra expression at day 15. Data are expressed as means ± SEM, n = 12. Statistical significance was assessed by one-way ANOVA (E) or by two-way ANOVA followed (F and G). In both cases, ANOVA test's were followed Tukey's multiple comparisons test. In case of A-D, test of significance was restricted to comparing within group effects (vehicle and leptin treatment). *p < 0.05, **p < 0.01, and ***p < 0.001.
Bks.Cg +Lepr Db /+Lepr Db /Olahsd Mice, supplied by Harlan UK Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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AgResearch lepr db/+ mice
PYY(3 – 36) and Ex4 in combination increases <t>leptin</t> sensitivity and increases the concentration of circulating soluble leptin receptor. A-D) Accumulated food intake (kcal) and body weight change (g) 4h (A, B) and 20h (C, D) after leptin injection(5 mg/kg) at treatment day 10.E) Plasma leptin concentration (pM) at day 15, F: Plasma concentration of soluble leptin receptor (SLR) at day 15, and G: Hepatic Lepra expression at day 15. Data are expressed as means ± SEM, n = 12. Statistical significance was assessed by one-way ANOVA (E) or by two-way ANOVA followed (F and G). In both cases, ANOVA test's were followed Tukey's multiple comparisons test. In case of A-D, test of significance was restricted to comparing within group effects (vehicle and leptin treatment). *p < 0.05, **p < 0.01, and ***p < 0.001.
Lepr Db/+ Mice, supplied by AgResearch, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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clea japan inc db / db ( lepr +/− ) mice
PYY(3 – 36) and Ex4 in combination increases <t>leptin</t> sensitivity and increases the concentration of circulating soluble leptin receptor. A-D) Accumulated food intake (kcal) and body weight change (g) 4h (A, B) and 20h (C, D) after leptin injection(5 mg/kg) at treatment day 10.E) Plasma leptin concentration (pM) at day 15, F: Plasma concentration of soluble leptin receptor (SLR) at day 15, and G: Hepatic Lepra expression at day 15. Data are expressed as means ± SEM, n = 12. Statistical significance was assessed by one-way ANOVA (E) or by two-way ANOVA followed (F and G). In both cases, ANOVA test's were followed Tukey's multiple comparisons test. In case of A-D, test of significance was restricted to comparing within group effects (vehicle and leptin treatment). *p < 0.05, **p < 0.01, and ***p < 0.001.
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Syagen Technology Inc bks (d)- lepr db /j
PYY(3 – 36) and Ex4 in combination increases <t>leptin</t> sensitivity and increases the concentration of circulating soluble leptin receptor. A-D) Accumulated food intake (kcal) and body weight change (g) 4h (A, B) and 20h (C, D) after leptin injection(5 mg/kg) at treatment day 10.E) Plasma leptin concentration (pM) at day 15, F: Plasma concentration of soluble leptin receptor (SLR) at day 15, and G: Hepatic Lepra expression at day 15. Data are expressed as means ± SEM, n = 12. Statistical significance was assessed by one-way ANOVA (E) or by two-way ANOVA followed (F and G). In both cases, ANOVA test's were followed Tukey's multiple comparisons test. In case of A-D, test of significance was restricted to comparing within group effects (vehicle and leptin treatment). *p < 0.05, **p < 0.01, and ***p < 0.001.
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Image Search Results


Hypothalamic leptin receptor knockdown attenuates the adipose redistribution-associated with unilateral iWAT injection of Rec2-Cre in male PTEN flox mice. (A) Experimental design. (B) Hypothalamic Lepr expression. (C) iWAT weight at sacrifice. (D) Ratio of Rec2-treated iWAT to the untreated contralateral iWAT. (E) Relative mRNA expression of leptin in iWAT. (F) Ratio of leptin mRNA between Rec2-treated iWAT and untreated contralateral iWAT. Data are means ± SEM. n = 6–7 per group for body weight and tissue weight data. n = 4–6 for qPCR data. *P < 0.05, **P < 0.01, ***P < 0.001.

Journal: Molecular Metabolism

Article Title: Adipose PTEN regulates adult adipose tissue homeostasis and redistribution via a PTEN-leptin-sympathetic loop

doi: 10.1016/j.molmet.2019.09.008

Figure Lengend Snippet: Hypothalamic leptin receptor knockdown attenuates the adipose redistribution-associated with unilateral iWAT injection of Rec2-Cre in male PTEN flox mice. (A) Experimental design. (B) Hypothalamic Lepr expression. (C) iWAT weight at sacrifice. (D) Ratio of Rec2-treated iWAT to the untreated contralateral iWAT. (E) Relative mRNA expression of leptin in iWAT. (F) Ratio of leptin mRNA between Rec2-treated iWAT and untreated contralateral iWAT. Data are means ± SEM. n = 6–7 per group for body weight and tissue weight data. n = 4–6 for qPCR data. *P < 0.05, **P < 0.01, ***P < 0.001.

Article Snippet: To select the most effective microRNA, the miR-Lepr expressing plasmids were co-transfected with a LepR expression plasmid (Lepr, MR226855, ORIGENE) to HEK293T cells.

Techniques: Injection, Expressing

PYY(3 – 36) and Ex4 in combination increases leptin sensitivity and increases the concentration of circulating soluble leptin receptor. A-D) Accumulated food intake (kcal) and body weight change (g) 4h (A, B) and 20h (C, D) after leptin injection(5 mg/kg) at treatment day 10.E) Plasma leptin concentration (pM) at day 15, F: Plasma concentration of soluble leptin receptor (SLR) at day 15, and G: Hepatic Lepra expression at day 15. Data are expressed as means ± SEM, n = 12. Statistical significance was assessed by one-way ANOVA (E) or by two-way ANOVA followed (F and G). In both cases, ANOVA test's were followed Tukey's multiple comparisons test. In case of A-D, test of significance was restricted to comparing within group effects (vehicle and leptin treatment). *p < 0.05, **p < 0.01, and ***p < 0.001.

Journal: Heliyon

Article Title: Improved leptin sensitivity and increased soluble leptin receptor concentrations may underlie the additive effects of combining PYY [ [1] , [2] , [3] , [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] ] and exendin-4 on body weight lowering in diet-induced obese mice

doi: 10.1016/j.heliyon.2024.e32009

Figure Lengend Snippet: PYY(3 – 36) and Ex4 in combination increases leptin sensitivity and increases the concentration of circulating soluble leptin receptor. A-D) Accumulated food intake (kcal) and body weight change (g) 4h (A, B) and 20h (C, D) after leptin injection(5 mg/kg) at treatment day 10.E) Plasma leptin concentration (pM) at day 15, F: Plasma concentration of soluble leptin receptor (SLR) at day 15, and G: Hepatic Lepra expression at day 15. Data are expressed as means ± SEM, n = 12. Statistical significance was assessed by one-way ANOVA (E) or by two-way ANOVA followed (F and G). In both cases, ANOVA test's were followed Tukey's multiple comparisons test. In case of A-D, test of significance was restricted to comparing within group effects (vehicle and leptin treatment). *p < 0.05, **p < 0.01, and ***p < 0.001.

Article Snippet: Soluble leptin receptor was analysed by a mouse leptin receptor picokine ELISA kit (BOSTER biological technology, Cat # EK0440).

Techniques: Concentration Assay, Injection, Clinical Proteomics, Expressing