ipc298 cell line Search Results


99
ATCC cancer cell lines
Cancer Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ATCC cell culture cell lines
Cell Culture Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
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93
DSMZ ipc 298 human melanoma cell lines
Ipc 298 Human Melanoma Cell Lines, supplied by DSMZ, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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99
ATCC cell lines
Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ipc298+cell+line/pmc08888590-318-1-14?v=ATCC
Average 99 stars, based on 1 article reviews
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90
Array BioPharma skmel28 cell line
(A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for <t>IPC298</t> CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.
Skmel28 Cell Line, supplied by Array BioPharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ipc298+cell+line/bio_rxiv__2022__01__10__475285-173-4-18?v=Array+BioPharma
Average 90 stars, based on 1 article reviews
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90
Array BioPharma ipc298 cell line
(A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for <t>IPC298</t> CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.
Ipc298 Cell Line, supplied by Array BioPharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ipc298+cell+line/pmc09894220-150-4-15?v=Array+BioPharma
Average 90 stars, based on 1 article reviews
ipc298 cell line - by Bioz Stars, 2026-07
90/100 stars
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90
Genentech inc belvarafenib-resistant ipc-298 cell lines
(A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for <t>IPC298</t> CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.
Belvarafenib Resistant Ipc 298 Cell Lines, supplied by Genentech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ipc298+cell+line/pm33953400-368-0-26?v=Genentech+inc
Average 90 stars, based on 1 article reviews
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99
ATCC invasion human malignant melanoma cell lines
(A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for <t>IPC298</t> CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.
Invasion Human Malignant Melanoma Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ipc298+cell+line/pm26446958-105-8-21?v=ATCC
Average 99 stars, based on 1 article reviews
invasion human malignant melanoma cell lines - by Bioz Stars, 2026-07
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Image Search Results


(A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for IPC298 CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.

Journal: bioRxiv

Article Title: MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas

doi: 10.1101/2022.01.10.475285

Figure Lengend Snippet: (A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for IPC298 CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.

Article Snippet: SKMEL5, SKMEL28, SKMEL2, and IPC298 cell lines were used for cell line xenograft (CLX) analyses in collaboration with Array Biopharma.

Techniques: Expressing, Inhibition, Standard Deviation