intact Search Results


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KCAS Bioanalytical and Biomarker Services biomarkers limonene
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Unigene protein 3 source type score intact
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Quidel intact fgf23
Effect of treatments on <t>iFGF23</t> and 1,25D‐regulating enzyme expression. (a) Intact <t>FGF23</t> (iFGF23) in the EPO cohort was markedly elevated in CKD‐saline mice compared to the casein control diet mice. EPO administration in the casein diet group had no effect on FGF23 compared to saline‐injected mice. Importantly, iFGF23 was lowered in CKD mice treated with EPO by over 70%. (b) In the FG cohort, the adenine diet induced iFGF23, which remained elevated in saline‐treated mice. FG‐4592 (“FG”) treatment in CKD mice significantly reduced iFGF23 levels by over 70% compared to saline controls. The dashed line in each graph indicates where diet was switched from 0.2% adenine to 0.15% adenine for the remainder of the study. The shaded area indicates the treatment window with either EPO or FG‐4592. (c) In the EPO‐treated cohort, renal Cyp27b1 mRNA remained unchanged in mice with CKD compared to casein controls, and EPO treatment significantly induced its expression. (d) Cyp24a1 mRNA was increased in mice with CKD compared with controls, and there was no significant difference in expression in the EPO‐CKD mice. (e) In the FG‐4592 treated cohort, Cyp27b1 mRNA was significantly elevated with FG‐4592 treatment in both diets with no difference between the diets. (f) Cyp24a1 expression was elevated in the mice with CKD, and this was reduced to control levels with FG‐4592 treatment ( n = 3–8 mice per group; * p < .05;** p < .01 CKD Saline versus Casein‐Saline, # p < .05; ## p < .01 CKD‐EPO/FG versus CKD Saline via two‐way ANOVA with a Tukey post hoc test or Student's t test where appropriate)
Intact Fgf23, supplied by Quidel, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Elabscience Biotechnology mouse i pth elisa kit
Effect of treatments on <t>iFGF23</t> and 1,25D‐regulating enzyme expression. (a) Intact <t>FGF23</t> (iFGF23) in the EPO cohort was markedly elevated in CKD‐saline mice compared to the casein control diet mice. EPO administration in the casein diet group had no effect on FGF23 compared to saline‐injected mice. Importantly, iFGF23 was lowered in CKD mice treated with EPO by over 70%. (b) In the FG cohort, the adenine diet induced iFGF23, which remained elevated in saline‐treated mice. FG‐4592 (“FG”) treatment in CKD mice significantly reduced iFGF23 levels by over 70% compared to saline controls. The dashed line in each graph indicates where diet was switched from 0.2% adenine to 0.15% adenine for the remainder of the study. The shaded area indicates the treatment window with either EPO or FG‐4592. (c) In the EPO‐treated cohort, renal Cyp27b1 mRNA remained unchanged in mice with CKD compared to casein controls, and EPO treatment significantly induced its expression. (d) Cyp24a1 mRNA was increased in mice with CKD compared with controls, and there was no significant difference in expression in the EPO‐CKD mice. (e) In the FG‐4592 treated cohort, Cyp27b1 mRNA was significantly elevated with FG‐4592 treatment in both diets with no difference between the diets. (f) Cyp24a1 expression was elevated in the mice with CKD, and this was reduced to control levels with FG‐4592 treatment ( n = 3–8 mice per group; * p < .05;** p < .01 CKD Saline versus Casein‐Saline, # p < .05; ## p < .01 CKD‐EPO/FG versus CKD Saline via two‐way ANOVA with a Tukey post hoc test or Student's t test where appropriate)
Mouse I Pth Elisa Kit, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BioVendor Instruments intact human proinsulin
Effect of treatments on <t>iFGF23</t> and 1,25D‐regulating enzyme expression. (a) Intact <t>FGF23</t> (iFGF23) in the EPO cohort was markedly elevated in CKD‐saline mice compared to the casein control diet mice. EPO administration in the casein diet group had no effect on FGF23 compared to saline‐injected mice. Importantly, iFGF23 was lowered in CKD mice treated with EPO by over 70%. (b) In the FG cohort, the adenine diet induced iFGF23, which remained elevated in saline‐treated mice. FG‐4592 (“FG”) treatment in CKD mice significantly reduced iFGF23 levels by over 70% compared to saline controls. The dashed line in each graph indicates where diet was switched from 0.2% adenine to 0.15% adenine for the remainder of the study. The shaded area indicates the treatment window with either EPO or FG‐4592. (c) In the EPO‐treated cohort, renal Cyp27b1 mRNA remained unchanged in mice with CKD compared to casein controls, and EPO treatment significantly induced its expression. (d) Cyp24a1 mRNA was increased in mice with CKD compared with controls, and there was no significant difference in expression in the EPO‐CKD mice. (e) In the FG‐4592 treated cohort, Cyp27b1 mRNA was significantly elevated with FG‐4592 treatment in both diets with no difference between the diets. (f) Cyp24a1 expression was elevated in the mice with CKD, and this was reduced to control levels with FG‐4592 treatment ( n = 3–8 mice per group; * p < .05;** p < .01 CKD Saline versus Casein‐Saline, # p < .05; ## p < .01 CKD‐EPO/FG versus CKD Saline via two‐way ANOVA with a Tukey post hoc test or Student's t test where appropriate)
Intact Human Proinsulin, supplied by BioVendor Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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85
Immundiagnostik AG proinsulin
Effect of treatments on <t>iFGF23</t> and 1,25D‐regulating enzyme expression. (a) Intact <t>FGF23</t> (iFGF23) in the EPO cohort was markedly elevated in CKD‐saline mice compared to the casein control diet mice. EPO administration in the casein diet group had no effect on FGF23 compared to saline‐injected mice. Importantly, iFGF23 was lowered in CKD mice treated with EPO by over 70%. (b) In the FG cohort, the adenine diet induced iFGF23, which remained elevated in saline‐treated mice. FG‐4592 (“FG”) treatment in CKD mice significantly reduced iFGF23 levels by over 70% compared to saline controls. The dashed line in each graph indicates where diet was switched from 0.2% adenine to 0.15% adenine for the remainder of the study. The shaded area indicates the treatment window with either EPO or FG‐4592. (c) In the EPO‐treated cohort, renal Cyp27b1 mRNA remained unchanged in mice with CKD compared to casein controls, and EPO treatment significantly induced its expression. (d) Cyp24a1 mRNA was increased in mice with CKD compared with controls, and there was no significant difference in expression in the EPO‐CKD mice. (e) In the FG‐4592 treated cohort, Cyp27b1 mRNA was significantly elevated with FG‐4592 treatment in both diets with no difference between the diets. (f) Cyp24a1 expression was elevated in the mice with CKD, and this was reduced to control levels with FG‐4592 treatment ( n = 3–8 mice per group; * p < .05;** p < .01 CKD Saline versus Casein‐Saline, # p < .05; ## p < .01 CKD‐EPO/FG versus CKD Saline via two‐way ANOVA with a Tukey post hoc test or Student's t test where appropriate)
Proinsulin, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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93
Eagle Biosciences human intact fgf21 elisa
Effect of treatments on <t>iFGF23</t> and 1,25D‐regulating enzyme expression. (a) Intact <t>FGF23</t> (iFGF23) in the EPO cohort was markedly elevated in CKD‐saline mice compared to the casein control diet mice. EPO administration in the casein diet group had no effect on FGF23 compared to saline‐injected mice. Importantly, iFGF23 was lowered in CKD mice treated with EPO by over 70%. (b) In the FG cohort, the adenine diet induced iFGF23, which remained elevated in saline‐treated mice. FG‐4592 (“FG”) treatment in CKD mice significantly reduced iFGF23 levels by over 70% compared to saline controls. The dashed line in each graph indicates where diet was switched from 0.2% adenine to 0.15% adenine for the remainder of the study. The shaded area indicates the treatment window with either EPO or FG‐4592. (c) In the EPO‐treated cohort, renal Cyp27b1 mRNA remained unchanged in mice with CKD compared to casein controls, and EPO treatment significantly induced its expression. (d) Cyp24a1 mRNA was increased in mice with CKD compared with controls, and there was no significant difference in expression in the EPO‐CKD mice. (e) In the FG‐4592 treated cohort, Cyp27b1 mRNA was significantly elevated with FG‐4592 treatment in both diets with no difference between the diets. (f) Cyp24a1 expression was elevated in the mice with CKD, and this was reduced to control levels with FG‐4592 treatment ( n = 3–8 mice per group; * p < .05;** p < .01 CKD Saline versus Casein‐Saline, # p < .05; ## p < .01 CKD‐EPO/FG versus CKD Saline via two‐way ANOVA with a Tukey post hoc test or Student's t test where appropriate)
Human Intact Fgf21 Elisa, supplied by Eagle Biosciences, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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93
Addgene inc itam intact backbone
Effect of treatments on <t>iFGF23</t> and 1,25D‐regulating enzyme expression. (a) Intact <t>FGF23</t> (iFGF23) in the EPO cohort was markedly elevated in CKD‐saline mice compared to the casein control diet mice. EPO administration in the casein diet group had no effect on FGF23 compared to saline‐injected mice. Importantly, iFGF23 was lowered in CKD mice treated with EPO by over 70%. (b) In the FG cohort, the adenine diet induced iFGF23, which remained elevated in saline‐treated mice. FG‐4592 (“FG”) treatment in CKD mice significantly reduced iFGF23 levels by over 70% compared to saline controls. The dashed line in each graph indicates where diet was switched from 0.2% adenine to 0.15% adenine for the remainder of the study. The shaded area indicates the treatment window with either EPO or FG‐4592. (c) In the EPO‐treated cohort, renal Cyp27b1 mRNA remained unchanged in mice with CKD compared to casein controls, and EPO treatment significantly induced its expression. (d) Cyp24a1 mRNA was increased in mice with CKD compared with controls, and there was no significant difference in expression in the EPO‐CKD mice. (e) In the FG‐4592 treated cohort, Cyp27b1 mRNA was significantly elevated with FG‐4592 treatment in both diets with no difference between the diets. (f) Cyp24a1 expression was elevated in the mice with CKD, and this was reduced to control levels with FG‐4592 treatment ( n = 3–8 mice per group; * p < .05;** p < .01 CKD Saline versus Casein‐Saline, # p < .05; ## p < .01 CKD‐EPO/FG versus CKD Saline via two‐way ANOVA with a Tukey post hoc test or Student's t test where appropriate)
Itam Intact Backbone, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Elabscience Biotechnology rat i pth intact parathormone elisa kit
Assay Kits used in the study.
Rat I Pth Intact Parathormone Elisa Kit, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Assay Kits used in the study.
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ALPCO fgf21 elisa
Assay Kits used in the study.
Fgf21 Elisa, supplied by ALPCO, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Effect of treatments on iFGF23 and 1,25D‐regulating enzyme expression. (a) Intact FGF23 (iFGF23) in the EPO cohort was markedly elevated in CKD‐saline mice compared to the casein control diet mice. EPO administration in the casein diet group had no effect on FGF23 compared to saline‐injected mice. Importantly, iFGF23 was lowered in CKD mice treated with EPO by over 70%. (b) In the FG cohort, the adenine diet induced iFGF23, which remained elevated in saline‐treated mice. FG‐4592 (“FG”) treatment in CKD mice significantly reduced iFGF23 levels by over 70% compared to saline controls. The dashed line in each graph indicates where diet was switched from 0.2% adenine to 0.15% adenine for the remainder of the study. The shaded area indicates the treatment window with either EPO or FG‐4592. (c) In the EPO‐treated cohort, renal Cyp27b1 mRNA remained unchanged in mice with CKD compared to casein controls, and EPO treatment significantly induced its expression. (d) Cyp24a1 mRNA was increased in mice with CKD compared with controls, and there was no significant difference in expression in the EPO‐CKD mice. (e) In the FG‐4592 treated cohort, Cyp27b1 mRNA was significantly elevated with FG‐4592 treatment in both diets with no difference between the diets. (f) Cyp24a1 expression was elevated in the mice with CKD, and this was reduced to control levels with FG‐4592 treatment ( n = 3–8 mice per group; * p < .05;** p < .01 CKD Saline versus Casein‐Saline, # p < .05; ## p < .01 CKD‐EPO/FG versus CKD Saline via two‐way ANOVA with a Tukey post hoc test or Student's t test where appropriate)

Journal: Physiological Reports

Article Title: Erythropoietin and a hypoxia‐inducible factor prolyl hydroxylase inhibitor (HIF‐PHDi) lowers FGF23 in a model of chronic kidney disease (CKD)

doi: 10.14814/phy2.14434

Figure Lengend Snippet: Effect of treatments on iFGF23 and 1,25D‐regulating enzyme expression. (a) Intact FGF23 (iFGF23) in the EPO cohort was markedly elevated in CKD‐saline mice compared to the casein control diet mice. EPO administration in the casein diet group had no effect on FGF23 compared to saline‐injected mice. Importantly, iFGF23 was lowered in CKD mice treated with EPO by over 70%. (b) In the FG cohort, the adenine diet induced iFGF23, which remained elevated in saline‐treated mice. FG‐4592 (“FG”) treatment in CKD mice significantly reduced iFGF23 levels by over 70% compared to saline controls. The dashed line in each graph indicates where diet was switched from 0.2% adenine to 0.15% adenine for the remainder of the study. The shaded area indicates the treatment window with either EPO or FG‐4592. (c) In the EPO‐treated cohort, renal Cyp27b1 mRNA remained unchanged in mice with CKD compared to casein controls, and EPO treatment significantly induced its expression. (d) Cyp24a1 mRNA was increased in mice with CKD compared with controls, and there was no significant difference in expression in the EPO‐CKD mice. (e) In the FG‐4592 treated cohort, Cyp27b1 mRNA was significantly elevated with FG‐4592 treatment in both diets with no difference between the diets. (f) Cyp24a1 expression was elevated in the mice with CKD, and this was reduced to control levels with FG‐4592 treatment ( n = 3–8 mice per group; * p < .05;** p < .01 CKD Saline versus Casein‐Saline, # p < .05; ## p < .01 CKD‐EPO/FG versus CKD Saline via two‐way ANOVA with a Tukey post hoc test or Student's t test where appropriate)

Article Snippet: Serum iFGF23 was assessed using a rodent‐specific commercial ELISA for bioactive, intact FGF23 (“iFGF23”; Quidel, Inc).

Techniques: Expressing, Saline, Control, Injection

Assay Kits used in the study.

Journal: Journal of Oral Biology and Craniofacial Research

Article Title: The effect of vitamin D deficiency on the RANKL/OPG ratio in rats

doi: 10.1016/j.jobcr.2022.02.004

Figure Lengend Snippet: Assay Kits used in the study.

Article Snippet: Rat I-PTH (Intact Parathormone) ELISA Kit , E-EL-R0535 96T , Serum PTH detection , Elabscience biotechnology Inc, China.

Techniques: Colorimetric Assay, Calcium Assay, Enzyme-linked Immunosorbent Assay