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inavolisib gdc-077 - by Bioz Stars,
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pi3kalpha inhibitor inavolisib Pi3kalpha Inhibitor Inavolisib, supplied by Genentech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/inavolisib/pm38518961-60-5-28?v=Genentech+inc Average 90 stars, based on 1 article reviews
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GDC-0077 (RG6114) is a potent, orally available, and selective PI3Kα inhibitor (IC50=0.038 nM). GDC-0077 (RG6114) exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3.
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