Journal: Journal of Clinical and Translational Research

Article Title: A literature review of microvascular proliferation in arteriovenous malformations of skin and soft tissue

doi:

Figure Lengend Snippet: Summary of 16 included articles

Article Snippet: Zhan et al. 2016 , 119 AVM=22 , Investigate AGGF1 expression in VM , Immunohistochemistry anti-AGGF1 , Chi square test , Of the 22 cases 21 Cases showed AGGF1 expression in plump endothelial cells. Only 2 of 16 flat endothelial cells showed AGGF1 expression. These findings indicate that preferential expression of AGGF1 in plump endothelial cells was applicable to AVM. Most mast cells also showed AGGF1. Did not correlate to the AGGF1 positive plump endothelial cells. Endothelial cells become plump when activated. AGGF1 expression was examined in HMC-1 cells. Strong granular staining was observed, indicating AGGF1 was contained in mast cell granules. Some parts had undetectable expression. AGGF1 is not specific for VM because vascular tumors also expressed AGGF1..

Techniques: Comparison, T-Test, Staining, Labeling, Activity Assay, Functional Assay, Shear, Standard Deviation, MANN-WHITNEY, Expressing, Control, Immunohistochemistry, Produced, Sampling, Immunofluorescence, Nucleic Acid Electrophoresis, Enzyme-linked Immunosorbent Assay, Mann-Whitney U-Test, Cell Culture, Concentration Assay, Immunohistochemical staining, Protein Concentration, Gene Expression