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Image Search Results
Journal: iScience
Article Title: Learning-dependent 4 Hz synchronization in the posterior striatum, lateral geniculate nucleus, and visual cortex
doi: 10.1016/j.isci.2025.113958
Figure Lengend Snippet: Entrainment of the pStr neuronal firing by 4 Hz oscillations (A) Phase modulation of the pStr neuron firing with respect to 4 Hz oscillations referenced to the pStr (top), dLGN (middle), and VC (bottom) during the early (left), middle (middle), and late (right) learning stages. Only significantly phase-modulated neurons are shown ( p < 0.05, Rayleigh test). The color scale represents the normalized firing rate of each neuron. The proportions of significantly phase-modulated neurons (early, middle, and late) were as follows: pStr-referenced, 22.9%, 18.9%, and 33.8%; dLGN-referenced, 22.9%, 22.3%, and 23.7%; and VC-referenced, 8.3%, 17.6%, and 20.2%. (B) Cumulative density function of phase modulation strength statistics log Z (Rayleigh Z statistic) for the pStr neurons. Green, blue, and purple lines represent the early, middle, and late stages, respectively. (C) Proportion of the pStr neurons phase-locked to 4 Hz oscillations referenced to the pStr (left), dLGN (middle), and VC (right) at each learning stage. Vertical bars represent the 95% confidence intervals (Clopper-Pearson method). (D) Histograms of preferred phase for the pStr neurons with respect to pStr (top), dLGN (middle), and VC (bottom) 4 Hz oscillations at the early (left), middle (middle), and late (right) learning stages. (E) Schematic of the hypothetical visual pathways conveying task-relevant information. After learning, the 4 Hz coherence between the pStr and visual areas increases, and a larger fraction of the pStr neurons is phase-modulated by visual-area 4 Hz oscillations. This strengthens functional connectivity between the pStr and visual areas, enabling rapid information transfer to downstream targets and improving task efficiency.
Article Snippet: The Kolmogorov-Smirnov test was applied to compare
Techniques: Functional Assay