hy-p2757 Search Results


phosphorylase kinase phk  (MedChemExpress)
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MedChemExpress phosphorylase kinase phk
Chemical structures of four BPU insecticides (Diflubenzuron, Teflubenzuron, Novaluron, and Flufenoxuron) and a human glycogen <t>phosphorylase</t> inhibitor (GPI) are shown. All share a central N,N’-diphenylurea (acylurea) core (dashed boxes). BPUs are characterized by halogenated (F, Cl) aromatic substituents and in some cases by additional ether or alkyl side chains. The GPI contains a methoxyphenyl group bearing an additional methylurea side chain. This structural similarity underpinned the hypothesis that insect GP might be a molecular target for BPUs.
Phosphorylase Kinase Phk, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-p2757/Phosphorylase+kinase/bio_rxiv__64898__2026__03__03__709364-199-7-12
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phosphorylase kinase phk - by Bioz Stars, 2026-10
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Chemical structures of four BPU insecticides (Diflubenzuron, Teflubenzuron, Novaluron, and Flufenoxuron) and a human glycogen phosphorylase inhibitor (GPI) are shown. All share a central N,N’-diphenylurea (acylurea) core (dashed boxes). BPUs are characterized by halogenated (F, Cl) aromatic substituents and in some cases by additional ether or alkyl side chains. The GPI contains a methoxyphenyl group bearing an additional methylurea side chain. This structural similarity underpinned the hypothesis that insect GP might be a molecular target for BPUs.

Journal: bioRxiv

Article Title: Metabolic compensation via gluconeogenesis explains the non-essentiality of glycogen phosphorylase as an insecticidal target in Plutella xylostella

doi: 10.64898/2026.03.03.709364

Figure Lengend Snippet: Chemical structures of four BPU insecticides (Diflubenzuron, Teflubenzuron, Novaluron, and Flufenoxuron) and a human glycogen phosphorylase inhibitor (GPI) are shown. All share a central N,N’-diphenylurea (acylurea) core (dashed boxes). BPUs are characterized by halogenated (F, Cl) aromatic substituents and in some cases by additional ether or alkyl side chains. The GPI contains a methoxyphenyl group bearing an additional methylurea side chain. This structural similarity underpinned the hypothesis that insect GP might be a molecular target for BPUs.

Article Snippet: Activation was performed in vitro using immobilized Phosphorylase Kinase (PhK) (Cat# HY-P2757, MedChemExpress, Monmouth Junction, NJ, USA).

Techniques: