hy-n1451 Search Results


betulonic acid  (MedChemExpress)
94
MedChemExpress betulonic acid
Discovery of small molecules targeting MSI2-dependent growth in colon cancer cells. (A , B) CCK8 assay of WT (blue) and MSI2 −/− (red) HCT116 cells upon treatment of Ro 08-2750 (A) or (-)Gossypol (B) for 72 h at indicated doses. Quantifications of three independent experiments were represented as mean ± SD. (C) Workflow of MSI2 inhibitor screening in MSI2-dependent colon cancer cells. Both WT and MSI2 −/− HCT116 cells were treated with a library of 1,109 natural compounds (10 μM) in parallel. Compounds with more than three-fold inhibition to WT compared to MSI2 −/− HCT116 cells in the first round of screening were selected for a next comparison in WT and MSI2 −/− cells in HCT116 paralleled to those of A549 cells. (D) Scatter plot showing the relative inhibition between WT and MSI2 −/− HCT116 cells in the first round of screening. Compounds for further confirmation were the dots above the red line. (E , F) CCK8 assay of WT and MSI2 −/− HCT116 (E) and A549 (F) cells upon treatment of <t>betulonic</t> acid, arctiin, shizukaol F, or palmatine at 10 μM for 72 h. Data were represented as mean ± SD of three independent experiments.
Betulonic Acid, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-n1451/Betulonic+acid/pmc08830500-42-0-12
Average 94 stars, based on 1 article reviews
betulonic acid - by Bioz Stars, 2026-10
94/100 stars
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oleanolic acid mce hy n0156 betulonic acid mce hy n1451 betulinic acid mce hy  (MedChemExpress)
94
MedChemExpress oleanolic acid mce hy n0156 betulonic acid mce hy n1451 betulinic acid mce hy
Discovery of small molecules targeting MSI2-dependent growth in colon cancer cells. (A , B) CCK8 assay of WT (blue) and MSI2 −/− (red) HCT116 cells upon treatment of Ro 08-2750 (A) or (-)Gossypol (B) for 72 h at indicated doses. Quantifications of three independent experiments were represented as mean ± SD. (C) Workflow of MSI2 inhibitor screening in MSI2-dependent colon cancer cells. Both WT and MSI2 −/− HCT116 cells were treated with a library of 1,109 natural compounds (10 μM) in parallel. Compounds with more than three-fold inhibition to WT compared to MSI2 −/− HCT116 cells in the first round of screening were selected for a next comparison in WT and MSI2 −/− cells in HCT116 paralleled to those of A549 cells. (D) Scatter plot showing the relative inhibition between WT and MSI2 −/− HCT116 cells in the first round of screening. Compounds for further confirmation were the dots above the red line. (E , F) CCK8 assay of WT and MSI2 −/− HCT116 (E) and A549 (F) cells upon treatment of <t>betulonic</t> acid, arctiin, shizukaol F, or palmatine at 10 μM for 72 h. Data were represented as mean ± SD of three independent experiments.
Oleanolic Acid Mce Hy N0156 Betulonic Acid Mce Hy N1451 Betulinic Acid Mce Hy, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-n1451/Oleanolic+acid/pm38729587-31-66-68
Average 94 stars, based on 1 article reviews
oleanolic acid mce hy n0156 betulonic acid mce hy n1451 betulinic acid mce hy - by Bioz Stars, 2026-10
94/100 stars
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oleanolic acid mce hy n0156 betulonic acid mce hy n1451 betulinic acid mce hy  (ATCC)
94
ATCC oleanolic acid mce hy n0156 betulonic acid mce hy n1451 betulinic acid mce hy
Discovery of small molecules targeting MSI2-dependent growth in colon cancer cells. (A , B) CCK8 assay of WT (blue) and MSI2 −/− (red) HCT116 cells upon treatment of Ro 08-2750 (A) or (-)Gossypol (B) for 72 h at indicated doses. Quantifications of three independent experiments were represented as mean ± SD. (C) Workflow of MSI2 inhibitor screening in MSI2-dependent colon cancer cells. Both WT and MSI2 −/− HCT116 cells were treated with a library of 1,109 natural compounds (10 μM) in parallel. Compounds with more than three-fold inhibition to WT compared to MSI2 −/− HCT116 cells in the first round of screening were selected for a next comparison in WT and MSI2 −/− cells in HCT116 paralleled to those of A549 cells. (D) Scatter plot showing the relative inhibition between WT and MSI2 −/− HCT116 cells in the first round of screening. Compounds for further confirmation were the dots above the red line. (E , F) CCK8 assay of WT and MSI2 −/− HCT116 (E) and A549 (F) cells upon treatment of <t>betulonic</t> acid, arctiin, shizukaol F, or palmatine at 10 μM for 72 h. Data were represented as mean ± SD of three independent experiments.
Oleanolic Acid Mce Hy N0156 Betulonic Acid Mce Hy N1451 Betulinic Acid Mce Hy, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hy-n1451/Glomerella+cingulata+(Stoneman)+Spaulding+et+Schrenk%2C+teleomorph/pm38729587-31-66-93
Average 94 stars, based on 1 article reviews
oleanolic acid mce hy n0156 betulonic acid mce hy n1451 betulinic acid mce hy - by Bioz Stars, 2026-10
94/100 stars
  Buy from Supplier
betulonic acid  (Chem Impex International)
N/A
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Image Search Results


Discovery of small molecules targeting MSI2-dependent growth in colon cancer cells. (A , B) CCK8 assay of WT (blue) and MSI2 −/− (red) HCT116 cells upon treatment of Ro 08-2750 (A) or (-)Gossypol (B) for 72 h at indicated doses. Quantifications of three independent experiments were represented as mean ± SD. (C) Workflow of MSI2 inhibitor screening in MSI2-dependent colon cancer cells. Both WT and MSI2 −/− HCT116 cells were treated with a library of 1,109 natural compounds (10 μM) in parallel. Compounds with more than three-fold inhibition to WT compared to MSI2 −/− HCT116 cells in the first round of screening were selected for a next comparison in WT and MSI2 −/− cells in HCT116 paralleled to those of A549 cells. (D) Scatter plot showing the relative inhibition between WT and MSI2 −/− HCT116 cells in the first round of screening. Compounds for further confirmation were the dots above the red line. (E , F) CCK8 assay of WT and MSI2 −/− HCT116 (E) and A549 (F) cells upon treatment of betulonic acid, arctiin, shizukaol F, or palmatine at 10 μM for 72 h. Data were represented as mean ± SD of three independent experiments.

Journal: Frontiers in Pharmacology

Article Title: Small Molecule Palmatine Targeting Musashi-2 in Colorectal Cancer

doi: 10.3389/fphar.2021.793449

Figure Lengend Snippet: Discovery of small molecules targeting MSI2-dependent growth in colon cancer cells. (A , B) CCK8 assay of WT (blue) and MSI2 −/− (red) HCT116 cells upon treatment of Ro 08-2750 (A) or (-)Gossypol (B) for 72 h at indicated doses. Quantifications of three independent experiments were represented as mean ± SD. (C) Workflow of MSI2 inhibitor screening in MSI2-dependent colon cancer cells. Both WT and MSI2 −/− HCT116 cells were treated with a library of 1,109 natural compounds (10 μM) in parallel. Compounds with more than three-fold inhibition to WT compared to MSI2 −/− HCT116 cells in the first round of screening were selected for a next comparison in WT and MSI2 −/− cells in HCT116 paralleled to those of A549 cells. (D) Scatter plot showing the relative inhibition between WT and MSI2 −/− HCT116 cells in the first round of screening. Compounds for further confirmation were the dots above the red line. (E , F) CCK8 assay of WT and MSI2 −/− HCT116 (E) and A549 (F) cells upon treatment of betulonic acid, arctiin, shizukaol F, or palmatine at 10 μM for 72 h. Data were represented as mean ± SD of three independent experiments.

Article Snippet: Betulonic acid (HY-N1451), arctiin (HY-N0034), and palmatine chloride (HY-N0110) were purchased from MedChemExpress.

Techniques: CCK-8 Assay, Inhibition, Comparison