human immunoglobulin ig g1 kappa monoclonal antibody Search Results


93
ProSci Incorporated trail r2
Trail R2, supplied by ProSci Incorporated, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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86
Millipore human immunoglobulin g1 kappa
Percentage survival was monitored using the xCELLigence RTCA of cetuximab-sensitive (Cet Sen ) cell lines ( a ), acquired cetuximab-resistant (Acq Res ) ( b ) and intrinsically cetuximab-resistant (Int Res ) cell lines which were either HPV-negative ( c ) or HPV-positive ( d ), until 48 h after treatment. Tumour cells were either treated with an isotype control <t>(IgG1κ)</t> or cetuximab [2 µg/ml], with or without healthy donor-derived NK cells (effector to target (E:T) ratio of 5:1) under both normoxic and hypoxic conditions. Fraction of ADCC induced killing was obtained by subtraction of the means of cetuximab and NK cells from cetuximab alone condition ( e ). Effect of hypoxia was determined within the different cetuximab resistance groups ( f ) and HPV status ( g ) within each group. Graphs represent mean ± SEM for each time point of follow up. Statistical significance was tested using a linear mixed model with Tukey’s pairwise comparison. NS not significant; * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001.
Human Immunoglobulin G1 Kappa, supplied by Millipore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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86
MedImmune llc human immunoglobulin g1 kappa igg1κ monoclonal antibody
Percentage survival was monitored using the xCELLigence RTCA of cetuximab-sensitive (Cet Sen ) cell lines ( a ), acquired cetuximab-resistant (Acq Res ) ( b ) and intrinsically cetuximab-resistant (Int Res ) cell lines which were either HPV-negative ( c ) or HPV-positive ( d ), until 48 h after treatment. Tumour cells were either treated with an isotype control <t>(IgG1κ)</t> or cetuximab [2 µg/ml], with or without healthy donor-derived NK cells (effector to target (E:T) ratio of 5:1) under both normoxic and hypoxic conditions. Fraction of ADCC induced killing was obtained by subtraction of the means of cetuximab and NK cells from cetuximab alone condition ( e ). Effect of hypoxia was determined within the different cetuximab resistance groups ( f ) and HPV status ( g ) within each group. Graphs represent mean ± SEM for each time point of follow up. Statistical significance was tested using a linear mixed model with Tukey’s pairwise comparison. NS not significant; * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001.
Human Immunoglobulin G1 Kappa Igg1κ Monoclonal Antibody, supplied by MedImmune llc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human immunoglobulin g1 kappa igg1κ monoclonal antibody/product/MedImmune llc
Average 86 stars, based on 1 article reviews
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86
Janssen human immunoglobulin g1 kappa igg1κ moa
Percentage survival was monitored using the xCELLigence RTCA of cetuximab-sensitive (Cet Sen ) cell lines ( a ), acquired cetuximab-resistant (Acq Res ) ( b ) and intrinsically cetuximab-resistant (Int Res ) cell lines which were either HPV-negative ( c ) or HPV-positive ( d ), until 48 h after treatment. Tumour cells were either treated with an isotype control <t>(IgG1κ)</t> or cetuximab [2 µg/ml], with or without healthy donor-derived NK cells (effector to target (E:T) ratio of 5:1) under both normoxic and hypoxic conditions. Fraction of ADCC induced killing was obtained by subtraction of the means of cetuximab and NK cells from cetuximab alone condition ( e ). Effect of hypoxia was determined within the different cetuximab resistance groups ( f ) and HPV status ( g ) within each group. Graphs represent mean ± SEM for each time point of follow up. Statistical significance was tested using a linear mixed model with Tukey’s pairwise comparison. NS not significant; * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001.
Human Immunoglobulin G1 Kappa Igg1κ Moa, supplied by Janssen, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human immunoglobulin g1 kappa igg1κ moa/product/Janssen
Average 86 stars, based on 1 article reviews
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Percentage survival was monitored using the xCELLigence RTCA of cetuximab-sensitive (Cet Sen ) cell lines ( a ), acquired cetuximab-resistant (Acq Res ) ( b ) and intrinsically cetuximab-resistant (Int Res ) cell lines which were either HPV-negative ( c ) or HPV-positive ( d ), until 48 h after treatment. Tumour cells were either treated with an isotype control (IgG1κ) or cetuximab [2 µg/ml], with or without healthy donor-derived NK cells (effector to target (E:T) ratio of 5:1) under both normoxic and hypoxic conditions. Fraction of ADCC induced killing was obtained by subtraction of the means of cetuximab and NK cells from cetuximab alone condition ( e ). Effect of hypoxia was determined within the different cetuximab resistance groups ( f ) and HPV status ( g ) within each group. Graphs represent mean ± SEM for each time point of follow up. Statistical significance was tested using a linear mixed model with Tukey’s pairwise comparison. NS not significant; * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001.

Journal: British Journal of Cancer

Article Title: Cetuximab-induced natural killer cell cytotoxicity in head and neck squamous cell carcinoma cell lines: investigation of the role of cetuximab sensitivity and HPV status

doi: 10.1038/s41416-020-0934-3

Figure Lengend Snippet: Percentage survival was monitored using the xCELLigence RTCA of cetuximab-sensitive (Cet Sen ) cell lines ( a ), acquired cetuximab-resistant (Acq Res ) ( b ) and intrinsically cetuximab-resistant (Int Res ) cell lines which were either HPV-negative ( c ) or HPV-positive ( d ), until 48 h after treatment. Tumour cells were either treated with an isotype control (IgG1κ) or cetuximab [2 µg/ml], with or without healthy donor-derived NK cells (effector to target (E:T) ratio of 5:1) under both normoxic and hypoxic conditions. Fraction of ADCC induced killing was obtained by subtraction of the means of cetuximab and NK cells from cetuximab alone condition ( e ). Effect of hypoxia was determined within the different cetuximab resistance groups ( f ) and HPV status ( g ) within each group. Graphs represent mean ± SEM for each time point of follow up. Statistical significance was tested using a linear mixed model with Tukey’s pairwise comparison. NS not significant; * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001.

Article Snippet: After overnight incubation, cetuximab [2 µg/ml] or human immunoglobulin G1 kappa (IgG1κ, [2 µg/ml]) (Sigma, 5154), as an isotype control was added.

Techniques: Derivative Assay