histogram Search Results


spike histogram software version 2 6 3  (ADInstruments)
94
ADInstruments spike histogram software version 2 6 3
Spike Histogram Software Version 2 6 3, supplied by ADInstruments, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/spike histogram software version 2 6 3/product/ADInstruments
Average 94 stars, based on 1 article reviews
spike histogram software version 2 6 3 - by Bioz Stars, 2026-04
94/100 stars
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spike histogram  (ADInstruments)
94
ADInstruments spike histogram
Spike Histogram, supplied by ADInstruments, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/spike histogram/product/ADInstruments
Average 94 stars, based on 1 article reviews
spike histogram - by Bioz Stars, 2026-04
94/100 stars
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spike histogram software  (ADInstruments)
94
ADInstruments spike histogram software
Spike Histogram Software, supplied by ADInstruments, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/spike histogram software/product/ADInstruments
Average 94 stars, based on 1 article reviews
spike histogram software - by Bioz Stars, 2026-04
94/100 stars
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chart 5 software spike histogram plug  (ADInstruments)
94
ADInstruments chart 5 software spike histogram plug
Chart 5 Software Spike Histogram Plug, supplied by ADInstruments, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/chart 5 software spike histogram plug/product/ADInstruments
Average 94 stars, based on 1 article reviews
chart 5 software spike histogram plug - by Bioz Stars, 2026-04
94/100 stars
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spike histogram feature  (ADInstruments)
95
ADInstruments spike histogram feature
Spike Histogram Feature, supplied by ADInstruments, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/spike histogram feature/product/ADInstruments
Average 95 stars, based on 1 article reviews
spike histogram feature - by Bioz Stars, 2026-04
95/100 stars
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alexa488 fluorescent intensity  (Carl Zeiss)
95
Carl Zeiss alexa488 fluorescent intensity
Small-molecule cyclophilin inhibitors inhibit coagulation induced by procoagulant platelets. ( A ) Whole blood was incubated with 125 µM F759 or F83236, 4 µM CsA before perfusion over a Horm collagen-coated surface in the presence of 6.6 mM CaCl 2 and 3.08 mM MgCl 2 . Shown are representative images after 9 min of top row: DIC images of platelet aggregates; middle row: anti-GpIb-VhH Alexa647 indicating platelets and bottom row: <t>tPA-Alexa488</t> binding to fibrin. ( B ) Quantification of Δ MFI anti-GpIb-VhH Alexa647 signal during 9 min. ( C ) MFI tPA-Alexa488 over time. ( D ) Quantification of Δ MFI tPA-Alexa488 signal during 9 min. Data represented as mean ± SD of 5–7 separate experiments. * p < 0.05 compared to vehicle by One-Way ANOVA. SMCypIs, small-molecule cyclophilin inhibitors; CsA, Cyclosporin A; tPA, tissue plasminogen activator.
Alexa488 Fluorescent Intensity, supplied by Carl Zeiss, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/alexa488 fluorescent intensity/product/Carl Zeiss
Average 95 stars, based on 1 article reviews
alexa488 fluorescent intensity - by Bioz Stars, 2026-04
95/100 stars
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spike histogram module  (ADInstruments)
94
ADInstruments spike histogram module
Small-molecule cyclophilin inhibitors inhibit coagulation induced by procoagulant platelets. ( A ) Whole blood was incubated with 125 µM F759 or F83236, 4 µM CsA before perfusion over a Horm collagen-coated surface in the presence of 6.6 mM CaCl 2 and 3.08 mM MgCl 2 . Shown are representative images after 9 min of top row: DIC images of platelet aggregates; middle row: anti-GpIb-VhH Alexa647 indicating platelets and bottom row: <t>tPA-Alexa488</t> binding to fibrin. ( B ) Quantification of Δ MFI anti-GpIb-VhH Alexa647 signal during 9 min. ( C ) MFI tPA-Alexa488 over time. ( D ) Quantification of Δ MFI tPA-Alexa488 signal during 9 min. Data represented as mean ± SD of 5–7 separate experiments. * p < 0.05 compared to vehicle by One-Way ANOVA. SMCypIs, small-molecule cyclophilin inhibitors; CsA, Cyclosporin A; tPA, tissue plasminogen activator.
Spike Histogram Module, supplied by ADInstruments, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/spike histogram module/product/ADInstruments
Average 94 stars, based on 1 article reviews
spike histogram module - by Bioz Stars, 2026-04
94/100 stars
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histogram tool  (Carl Zeiss)
90
Carl Zeiss histogram tool
Small-molecule cyclophilin inhibitors inhibit coagulation induced by procoagulant platelets. ( A ) Whole blood was incubated with 125 µM F759 or F83236, 4 µM CsA before perfusion over a Horm collagen-coated surface in the presence of 6.6 mM CaCl 2 and 3.08 mM MgCl 2 . Shown are representative images after 9 min of top row: DIC images of platelet aggregates; middle row: anti-GpIb-VhH Alexa647 indicating platelets and bottom row: <t>tPA-Alexa488</t> binding to fibrin. ( B ) Quantification of Δ MFI anti-GpIb-VhH Alexa647 signal during 9 min. ( C ) MFI tPA-Alexa488 over time. ( D ) Quantification of Δ MFI tPA-Alexa488 signal during 9 min. Data represented as mean ± SD of 5–7 separate experiments. * p < 0.05 compared to vehicle by One-Way ANOVA. SMCypIs, small-molecule cyclophilin inhibitors; CsA, Cyclosporin A; tPA, tissue plasminogen activator.
Histogram Tool, supplied by Carl Zeiss, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/histogram tool/product/Carl Zeiss
Average 90 stars, based on 1 article reviews
histogram tool - by Bioz Stars, 2026-04
90/100 stars
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pyramid of histograms of orientated hradients (phog)  (Carl Zeiss)
90
Carl Zeiss pyramid of histograms of orientated hradients (phog)
Small-molecule cyclophilin inhibitors inhibit coagulation induced by procoagulant platelets. ( A ) Whole blood was incubated with 125 µM F759 or F83236, 4 µM CsA before perfusion over a Horm collagen-coated surface in the presence of 6.6 mM CaCl 2 and 3.08 mM MgCl 2 . Shown are representative images after 9 min of top row: DIC images of platelet aggregates; middle row: anti-GpIb-VhH Alexa647 indicating platelets and bottom row: <t>tPA-Alexa488</t> binding to fibrin. ( B ) Quantification of Δ MFI anti-GpIb-VhH Alexa647 signal during 9 min. ( C ) MFI tPA-Alexa488 over time. ( D ) Quantification of Δ MFI tPA-Alexa488 signal during 9 min. Data represented as mean ± SD of 5–7 separate experiments. * p < 0.05 compared to vehicle by One-Way ANOVA. SMCypIs, small-molecule cyclophilin inhibitors; CsA, Cyclosporin A; tPA, tissue plasminogen activator.
Pyramid Of Histograms Of Orientated Hradients (Phog), supplied by Carl Zeiss, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pyramid of histograms of orientated hradients (phog)/product/Carl Zeiss
Average 90 stars, based on 1 article reviews
pyramid of histograms of orientated hradients (phog) - by Bioz Stars, 2026-04
90/100 stars
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histograms of upregulated genes  (GraphPad Software Inc)
90
GraphPad Software Inc histograms of upregulated genes
Small-molecule cyclophilin inhibitors inhibit coagulation induced by procoagulant platelets. ( A ) Whole blood was incubated with 125 µM F759 or F83236, 4 µM CsA before perfusion over a Horm collagen-coated surface in the presence of 6.6 mM CaCl 2 and 3.08 mM MgCl 2 . Shown are representative images after 9 min of top row: DIC images of platelet aggregates; middle row: anti-GpIb-VhH Alexa647 indicating platelets and bottom row: <t>tPA-Alexa488</t> binding to fibrin. ( B ) Quantification of Δ MFI anti-GpIb-VhH Alexa647 signal during 9 min. ( C ) MFI tPA-Alexa488 over time. ( D ) Quantification of Δ MFI tPA-Alexa488 signal during 9 min. Data represented as mean ± SD of 5–7 separate experiments. * p < 0.05 compared to vehicle by One-Way ANOVA. SMCypIs, small-molecule cyclophilin inhibitors; CsA, Cyclosporin A; tPA, tissue plasminogen activator.
Histograms Of Upregulated Genes, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/histograms of upregulated genes/product/GraphPad Software Inc
Average 90 stars, based on 1 article reviews
histograms of upregulated genes - by Bioz Stars, 2026-04
90/100 stars
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spike histogram for macintosh v2.2  (ADInstruments)
90
ADInstruments spike histogram for macintosh v2.2
Small-molecule cyclophilin inhibitors inhibit coagulation induced by procoagulant platelets. ( A ) Whole blood was incubated with 125 µM F759 or F83236, 4 µM CsA before perfusion over a Horm collagen-coated surface in the presence of 6.6 mM CaCl 2 and 3.08 mM MgCl 2 . Shown are representative images after 9 min of top row: DIC images of platelet aggregates; middle row: anti-GpIb-VhH Alexa647 indicating platelets and bottom row: <t>tPA-Alexa488</t> binding to fibrin. ( B ) Quantification of Δ MFI anti-GpIb-VhH Alexa647 signal during 9 min. ( C ) MFI tPA-Alexa488 over time. ( D ) Quantification of Δ MFI tPA-Alexa488 signal during 9 min. Data represented as mean ± SD of 5–7 separate experiments. * p < 0.05 compared to vehicle by One-Way ANOVA. SMCypIs, small-molecule cyclophilin inhibitors; CsA, Cyclosporin A; tPA, tissue plasminogen activator.
Spike Histogram For Macintosh V2.2, supplied by ADInstruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/spike histogram for macintosh v2.2/product/ADInstruments
Average 90 stars, based on 1 article reviews
spike histogram for macintosh v2.2 - by Bioz Stars, 2026-04
90/100 stars
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histogram chart  (Adcock Ingram)
90
Adcock Ingram histogram chart
Small-molecule cyclophilin inhibitors inhibit coagulation induced by procoagulant platelets. ( A ) Whole blood was incubated with 125 µM F759 or F83236, 4 µM CsA before perfusion over a Horm collagen-coated surface in the presence of 6.6 mM CaCl 2 and 3.08 mM MgCl 2 . Shown are representative images after 9 min of top row: DIC images of platelet aggregates; middle row: anti-GpIb-VhH Alexa647 indicating platelets and bottom row: <t>tPA-Alexa488</t> binding to fibrin. ( B ) Quantification of Δ MFI anti-GpIb-VhH Alexa647 signal during 9 min. ( C ) MFI tPA-Alexa488 over time. ( D ) Quantification of Δ MFI tPA-Alexa488 signal during 9 min. Data represented as mean ± SD of 5–7 separate experiments. * p < 0.05 compared to vehicle by One-Way ANOVA. SMCypIs, small-molecule cyclophilin inhibitors; CsA, Cyclosporin A; tPA, tissue plasminogen activator.
Histogram Chart, supplied by Adcock Ingram, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/histogram chart/product/Adcock Ingram
Average 90 stars, based on 1 article reviews
histogram chart - by Bioz Stars, 2026-04
90/100 stars
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Image Search Results


Small-molecule cyclophilin inhibitors inhibit coagulation induced by procoagulant platelets. ( A ) Whole blood was incubated with 125 µM F759 or F83236, 4 µM CsA before perfusion over a Horm collagen-coated surface in the presence of 6.6 mM CaCl 2 and 3.08 mM MgCl 2 . Shown are representative images after 9 min of top row: DIC images of platelet aggregates; middle row: anti-GpIb-VhH Alexa647 indicating platelets and bottom row: tPA-Alexa488 binding to fibrin. ( B ) Quantification of Δ MFI anti-GpIb-VhH Alexa647 signal during 9 min. ( C ) MFI tPA-Alexa488 over time. ( D ) Quantification of Δ MFI tPA-Alexa488 signal during 9 min. Data represented as mean ± SD of 5–7 separate experiments. * p < 0.05 compared to vehicle by One-Way ANOVA. SMCypIs, small-molecule cyclophilin inhibitors; CsA, Cyclosporin A; tPA, tissue plasminogen activator.

Journal: International Journal of Molecular Sciences

Article Title: Small-Molecule Cyclophilin Inhibitors Potently Reduce Platelet Procoagulant Activity

doi: 10.3390/ijms24087163

Figure Lengend Snippet: Small-molecule cyclophilin inhibitors inhibit coagulation induced by procoagulant platelets. ( A ) Whole blood was incubated with 125 µM F759 or F83236, 4 µM CsA before perfusion over a Horm collagen-coated surface in the presence of 6.6 mM CaCl 2 and 3.08 mM MgCl 2 . Shown are representative images after 9 min of top row: DIC images of platelet aggregates; middle row: anti-GpIb-VhH Alexa647 indicating platelets and bottom row: tPA-Alexa488 binding to fibrin. ( B ) Quantification of Δ MFI anti-GpIb-VhH Alexa647 signal during 9 min. ( C ) MFI tPA-Alexa488 over time. ( D ) Quantification of Δ MFI tPA-Alexa488 signal during 9 min. Data represented as mean ± SD of 5–7 separate experiments. * p < 0.05 compared to vehicle by One-Way ANOVA. SMCypIs, small-molecule cyclophilin inhibitors; CsA, Cyclosporin A; tPA, tissue plasminogen activator.

Article Snippet: Images were analyzed for the formation of fibrin via Alexa488 fluorescent intensity by the Image Analysis module within the ZEN2 Pro software (ZEISS Microscopy, Jena, Thüringen, Germany).

Techniques: Coagulation, Incubation, Binding Assay