hek293t-rex Search Results


98
AMS Biotechnology t-rex - hek293 recombinant cell line
T Rex Hek293 Recombinant Cell Line, supplied by AMS Biotechnology, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hek293t-rex/custom%4071227%40us09567378?v=AMS+Biotechnology
Average 98 stars, based on 1 article reviews
t-rex - hek293 recombinant cell line - by Bioz Stars, 2026-07
98/100 stars
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90
Redoxis Inc hek 293t-rex
Structure and inhibitory effects of GLX481304 Panel a and b show the chemical structure of GLX481304 and GLX481369 used as a redox control. Panel c show the IC values of GLX481304 for Nox 1 (open bar, in CHO cells, one technical duplicate), Nox 2 (hatched bar in human neutrophils, one technical duplicate) and Nox 4 (full bar in CJ HEK 293 cells, four measurements) isoforms. The maximal inhibition of <t>Nox4</t> was 116% and the Hill coefficient 0.94. Panel d shows the antioxidant effects (Y axis shows DPPH absorbance) of the structurally related compound GLX481369 (open circles, with half maximal effect at about 2.3 µM, thin line shows fit to hyperbolic equation) and lack of effects of the GLX481304 (filled circles). The GLX481369 redox active substance was identified and disqualified as a potential Nox4 inhibitor during a SAR development to improve Nox4 inhibitors. During this development GLX481369 was later instead used as control of being a redox active substance in the selection and identification of true Nox4 inhibitors. This substance was previously also used as an internal redox control in . Filled squares shows absorbance in DPPH without added compound and open squares the background fluorescence.
Hek 293t Rex, supplied by Redoxis Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hek293t-rex/pmc08184855-106-11-23?v=Redoxis+Inc
Average 90 stars, based on 1 article reviews
hek 293t-rex - by Bioz Stars, 2026-07
90/100 stars
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86
Biocoat 104 hek293 gfp cells
Structure and inhibitory effects of GLX481304 Panel a and b show the chemical structure of GLX481304 and GLX481369 used as a redox control. Panel c show the IC values of GLX481304 for Nox 1 (open bar, in CHO cells, one technical duplicate), Nox 2 (hatched bar in human neutrophils, one technical duplicate) and Nox 4 (full bar in CJ HEK 293 cells, four measurements) isoforms. The maximal inhibition of <t>Nox4</t> was 116% and the Hill coefficient 0.94. Panel d shows the antioxidant effects (Y axis shows DPPH absorbance) of the structurally related compound GLX481369 (open circles, with half maximal effect at about 2.3 µM, thin line shows fit to hyperbolic equation) and lack of effects of the GLX481304 (filled circles). The GLX481369 redox active substance was identified and disqualified as a potential Nox4 inhibitor during a SAR development to improve Nox4 inhibitors. During this development GLX481369 was later instead used as control of being a redox active substance in the selection and identification of true Nox4 inhibitors. This substance was previously also used as an internal redox control in . Filled squares shows absorbance in DPPH without added compound and open squares the background fluorescence.
104 Hek293 Gfp Cells, supplied by Biocoat, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hek293t-rex/us12559737-915-0-9?v=Biocoat
Average 86 stars, based on 1 article reviews
104 hek293 gfp cells - by Bioz Stars, 2026-07
86/100 stars
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Image Search Results


Structure and inhibitory effects of GLX481304 Panel a and b show the chemical structure of GLX481304 and GLX481369 used as a redox control. Panel c show the IC values of GLX481304 for Nox 1 (open bar, in CHO cells, one technical duplicate), Nox 2 (hatched bar in human neutrophils, one technical duplicate) and Nox 4 (full bar in CJ HEK 293 cells, four measurements) isoforms. The maximal inhibition of Nox4 was 116% and the Hill coefficient 0.94. Panel d shows the antioxidant effects (Y axis shows DPPH absorbance) of the structurally related compound GLX481369 (open circles, with half maximal effect at about 2.3 µM, thin line shows fit to hyperbolic equation) and lack of effects of the GLX481304 (filled circles). The GLX481369 redox active substance was identified and disqualified as a potential Nox4 inhibitor during a SAR development to improve Nox4 inhibitors. During this development GLX481369 was later instead used as control of being a redox active substance in the selection and identification of true Nox4 inhibitors. This substance was previously also used as an internal redox control in . Filled squares shows absorbance in DPPH without added compound and open squares the background fluorescence.

Journal: Scientific Reports

Article Title: A small molecule inhibitor of Nox2 and Nox4 improves contractile function after ischemia–reperfusion in the mouse heart

doi: 10.1038/s41598-021-91575-8

Figure Lengend Snippet: Structure and inhibitory effects of GLX481304 Panel a and b show the chemical structure of GLX481304 and GLX481369 used as a redox control. Panel c show the IC values of GLX481304 for Nox 1 (open bar, in CHO cells, one technical duplicate), Nox 2 (hatched bar in human neutrophils, one technical duplicate) and Nox 4 (full bar in CJ HEK 293 cells, four measurements) isoforms. The maximal inhibition of Nox4 was 116% and the Hill coefficient 0.94. Panel d shows the antioxidant effects (Y axis shows DPPH absorbance) of the structurally related compound GLX481369 (open circles, with half maximal effect at about 2.3 µM, thin line shows fit to hyperbolic equation) and lack of effects of the GLX481304 (filled circles). The GLX481369 redox active substance was identified and disqualified as a potential Nox4 inhibitor during a SAR development to improve Nox4 inhibitors. During this development GLX481369 was later instead used as control of being a redox active substance in the selection and identification of true Nox4 inhibitors. This substance was previously also used as an internal redox control in . Filled squares shows absorbance in DPPH without added compound and open squares the background fluorescence.

Article Snippet: Nox1 in CHO cells , Nox2 in human neutrophils , , Nox4 HEK 293T-Rex and CJ HEK 293 cells overexpressing Nox4 (purchased from Redoxis, Lund, Sweden).

Techniques: Control, Inhibition, Selection, Fluorescence