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Image Search Results
Journal: Scientific Reports
Article Title: Therapeutic effect of histone deacetylase 6 inhibitor for a mouse model of phenylketonuria
doi: 10.1038/s41598-025-29143-7
Figure Lengend Snippet: Western blot analysis of acetyl-HSP90, HSP90, and PAH protein expression in liver tissues from sham, treated, and wild-type groups following 12 weeks of TSA treatment. ( A ) Expression of acetyl-HSP90, HSP90, PAH, and GAPDH (used as a loading control). ( B ) Quantitative analysis of acetyl-HSP90 relative to HSP90 protein levels. ( C ) Quantitative analysis of PAH relative to GAPDH protein levels. The expression of PAE was quantified using the Image J software (Version 1.49) and expressed as arbitrary units (a.u.). Results are presented as mean ± SEM, with statistical significance indicated. ****P<0.0001.
Article Snippet: The antibodies used
Techniques: Western Blot, Expressing, Control, Software
Journal: Scientific Reports
Article Title: Therapeutic effect of histone deacetylase 6 inhibitor for a mouse model of phenylketonuria
doi: 10.1038/s41598-025-29143-7
Figure Lengend Snippet: Mechanism of TSA in enhancing HSP90 acetylation and stabilizing misfolded PAH protein to improve phenylalanine metabolism.
Article Snippet: The antibodies used
Techniques: