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Image Search Results
Journal: Tissue Engineering. Part A
Article Title: Influence of Adult Mesenchymal Stem Cells on In Vitro Vascular Formation
doi: 10.1089/ten.tea.2008.0254
Figure Lengend Snippet: BM-MSCs stabilize tubules formed on Matrigel. (A) Adult HDMVECs spontaneously form tubules on Matrigel when cultured in the presence of medium that contains proangiogenic factors, phase contrast optics, day 2 postseeding. (B) AD-MSCs coseeded with HDMVECs failed to stabilize tubules on Matrigel in the absence of exogenous proangiogenic factors, day 2 postseeding. The MSCs formed dense clusters on Matrigel (circled region) and failed to align. Combined phase contrast and fluorescence optics. (C) BM-MSCs coseeded with HDMVECs aligned with tubules and stabilized these structures when cultured in medium that lacked proangiogenic factors, day 10 postseeding. Arrows indicate BM-MSCs at sites of tubule branching. Combined phase contrast and fluorescence optics. (D) Multiple branches occurred at sites of higher concentrations of BM-MSCs, day 10 postseeding (circled region). Combined phase contrast and fluorescence optics. Scale bars: (A, B) 2 mm and (C, D) 500 μm.
Article Snippet:
Techniques: Cell Culture, Fluorescence