Journal: Microelectronic Engineering

Article Title: Diagnostic tools for tackling febrile illness and enhancing patient management

doi: 10.1016/j.mee.2018.10.001

Figure Lengend Snippet: Classification of fever-causing pathogens in Africa (parasitic, bacterial, viral, fungal systemic infections). “NA”: Not Applicable; “?”: unknown; “NAATs”: Nucleic Acid Amplification Technologies; “LFT”: Lateral Flow Test.

Article Snippet: Several technologies have been developed based on colorimetric (e.g. colloidal gold or colored latex) or fluorescence detection, by commercial suppliers: ESEQuant™ LFT strip reader by Qiagen Lake Constance (Germany); an imaging system by Axxin Inc. (Australia); the handheld image capture LFT reader by Detekt Biomedical, LCC (USA); the cPOC™ reader from LRE Medical (Germany); the handheld DCN Fluorescent Test Visualizer (USA) [ ].

Techniques: Amplification, Infection

Journal: Microelectronic Engineering

Article Title: Diagnostic tools for tackling febrile illness and enhancing patient management

doi: 10.1016/j.mee.2018.10.001

Figure Lengend Snippet: Overview of the described point-of-care and near-patient NAATs from the customer perspective.

Article Snippet: Several technologies have been developed based on colorimetric (e.g. colloidal gold or colored latex) or fluorescence detection, by commercial suppliers: ESEQuant™ LFT strip reader by Qiagen Lake Constance (Germany); an imaging system by Axxin Inc. (Australia); the handheld image capture LFT reader by Detekt Biomedical, LCC (USA); the cPOC™ reader from LRE Medical (Germany); the handheld DCN Fluorescent Test Visualizer (USA) [ ].

Techniques: Luminex

Journal: Microelectronic Engineering

Article Title: Diagnostic tools for tackling febrile illness and enhancing patient management

doi: 10.1016/j.mee.2018.10.001

Figure Lengend Snippet: The Q-POC™ system (handheld, smartphone-sized). Image source: used from .

Article Snippet: Several technologies have been developed based on colorimetric (e.g. colloidal gold or colored latex) or fluorescence detection, by commercial suppliers: ESEQuant™ LFT strip reader by Qiagen Lake Constance (Germany); an imaging system by Axxin Inc. (Australia); the handheld image capture LFT reader by Detekt Biomedical, LCC (USA); the cPOC™ reader from LRE Medical (Germany); the handheld DCN Fluorescent Test Visualizer (USA) [ ].

Techniques:

Journal: Microelectronic Engineering

Article Title: Diagnostic tools for tackling febrile illness and enhancing patient management

doi: 10.1016/j.mee.2018.10.001

Figure Lengend Snippet: Schematic of the Q-POC™ microfluidic chip. (a) Sample inlet. (b) Lysis chamber for releasing the DNA from the cells (or, with the use of appropriate membrane, for withholding the cells if circulating DNA is required for analysis). (c) Nucleic acid purification, by keeping all lysate components on a membrane. (d) Nucleic acid amplification area (continuous flow PCR). (e) Post-amplification and pre-analysis processing (its necessity depends on the application). (f) Connecting fluidic channel. (g) Metal contacts, providing the interface with the handheld device. (h) Sensitive SiNW arrays. (i) Meander-shaped microfluidic channel filled with reagents that are released at will to area (g)/(h). In particular, reagents may include various nucleotide mixtures and wash solutions, all separated by air bubble(s), in order to flow sequentially and in a well-controlled way. When nucleotides flow sequentially over a nanowire-immobilized single stranded oligonucleotide, then according to the hybridization sequence, the local charge changes, causing a resistance change in the SiNW. Image source: used from .

Article Snippet: Several technologies have been developed based on colorimetric (e.g. colloidal gold or colored latex) or fluorescence detection, by commercial suppliers: ESEQuant™ LFT strip reader by Qiagen Lake Constance (Germany); an imaging system by Axxin Inc. (Australia); the handheld image capture LFT reader by Detekt Biomedical, LCC (USA); the cPOC™ reader from LRE Medical (Germany); the handheld DCN Fluorescent Test Visualizer (USA) [ ].

Techniques: Lysis, Nucleic Acid Purification, Amplification, Hybridization, Sequencing

Journal: Microelectronic Engineering

Article Title: Diagnostic tools for tackling febrile illness and enhancing patient management

doi: 10.1016/j.mee.2018.10.001

Figure Lengend Snippet: The EasyNAT™ cartridge from Ustar Biotechnologies (Hangzhou) Ltd. (handheld size). The integrated lateral flow test is visible. Image source: used from .

Article Snippet: Several technologies have been developed based on colorimetric (e.g. colloidal gold or colored latex) or fluorescence detection, by commercial suppliers: ESEQuant™ LFT strip reader by Qiagen Lake Constance (Germany); an imaging system by Axxin Inc. (Australia); the handheld image capture LFT reader by Detekt Biomedical, LCC (USA); the cPOC™ reader from LRE Medical (Germany); the handheld DCN Fluorescent Test Visualizer (USA) [ ].

Techniques:

Journal: Theranostics

Article Title: Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology

doi: 10.7150/thno.9899

Figure Lengend Snippet: Parameter comparison of image-guided systems.

Article Snippet: 3 , Photodynamic Eye , Hamamatsu Photonics, Hamamatsu, Japan , Handheld Fluorescence Imaging , 760 , 100*67 , Not specified , Not specified , 8 , 200 , No , LED , FDA approved , www.hamamatsu.com.

Techniques: Comparison, Imaging, Fluorescence

Journal: Theranostics

Article Title: Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology

doi: 10.7150/thno.9899

Figure Lengend Snippet: Clinical application results using surgical navigation systems. a) SPY imaging demonstrates perfusion to the thumb, index, and middle fingers via scanning with indocyanine green , b) Instructions for the Artemis Handheld system, c) Intraoperative NIR fluorescent image of the Fluobeam camera system , d) fluorescent signal and/or blue color of lymph nodes detected by PDE , e) Single SLN identification by the FLARE system , f) In vivo fluorescence imaging of a lymph node detected by the Multispectral FMI system , g) ICG-guided intraoperative detection and resection of the SLN in humans by the surgical navigation system GXMI Navigator .

Article Snippet: 3 , Photodynamic Eye , Hamamatsu Photonics, Hamamatsu, Japan , Handheld Fluorescence Imaging , 760 , 100*67 , Not specified , Not specified , 8 , 200 , No , LED , FDA approved , www.hamamatsu.com.

Techniques: Imaging, In Vivo, Fluorescence

Journal: Contrast Media & Molecular Imaging

Article Title: 99m Tc- 68 Ga-ICG-Labelled Macroaggregates and Nanocolloids of Human Serum Albumin: Synthesis Procedures of a Trimodal Imaging Agent Using Commercial Kits

doi: 10.1155/2020/3629705

Figure Lengend Snippet: ITLC strips (picture of PDE output). ICG fluorescence remains mostly at the MAA-labelled point of application even though about 10 % of the dye was found free in the solution.

Article Snippet: The fluorescence tagging yield was detected on the same ITLC-SG strip with a handheld fluorescence imager PDE probe (PhotoDynamicEye Hamamatsu by SEDA S.P.A. Italy).

Techniques: Fluorescence

Journal: Contrast Media & Molecular Imaging

Article Title: 99m Tc- 68 Ga-ICG-Labelled Macroaggregates and Nanocolloids of Human Serum Albumin: Synthesis Procedures of a Trimodal Imaging Agent Using Commercial Kits

doi: 10.1155/2020/3629705

Figure Lengend Snippet: PDE probe (PhotoDynamicEye Hamamatsu by SEDA S.P.A. Italy) handheld fluorescence imager.

Article Snippet: The fluorescence tagging yield was detected on the same ITLC-SG strip with a handheld fluorescence imager PDE probe (PhotoDynamicEye Hamamatsu by SEDA S.P.A. Italy).

Techniques: Fluorescence