Journal: Science Advances

Article Title: Experience-dependent plasticity of gustatory insular cortex circuits and taste preferences

doi: 10.1126/sciadv.ade6561

Figure Lengend Snippet: ( A ) Left: Representation of Davis rig gustometer. Top right: Schedule for EE and testing. Bottom right: Sequence of taste solutions. ( B ) Left: Sucrose curves from naïve mice by age group. A single curve fitted all datasets ( P = 0.071, F test). Right: Slopes of sucrose curves for naïve mice ( P = 0.040, one-way analysis of variance (ANOVA); P35 versus P91, P = 0.035, post hoc Bonferroni test). ( C ) Left: Sucrose curve for P56 naïve (black) and EE (gray) mice. Separate curves were needed to fit the datasets ( P < 0.001, F test). Right: Slope of P56 naïve (white) and EE (gray) sucrose curves ( P = 1.831 × 10 −11 , unpaired two-tailed t test). ( D ) Left: Sucrose curves for P56 mice in modified EE. Separate curves were needed for Ensure ( P < 0.001, F test), while a single curve was sufficient to fit naïve (black), NaCl (purple), and sucrose (red) ( P = 0.115, F test). Right: Slope of sucrose curves. White, naïve; green, Ensure EE; purple, NaCl EE; red, sucrose EE (naïve versus Ensure, P = 4.69 × 10 −11 ; naïve versus sucrose, P = 0.423; naïve versus salt, P = 0.290; one-way ANOVA with post hoc Bonferroni t test). For (B) to (D), dark line, curve fit; dotted lines, 95% CIs. Dotted gray line plotted at 1 shows water lick rate (0 mM sucrose). Data points, means ± SEM. ( E and F ) Analysis of licking for P55 to P58 naïve and EE mice tested on a 30-min trial of access to water or 200 mM sucrose. (E) Lick raster plots for water (top) and sucrose (bottom). Shaded area, licks by mice in the EE group. (F) Left: Accumulation of licks to water from naïve (black) and EE (gray) mice ( P = 8.2 × 10 −10 , Mann-Whitney U test). Right: Accumulation of licks to sucrose in naïve (black) and EE (gray) mice ( P = 5.2 × 10 −5 , Mann-Whitney U test). Asterisks indicate P ≤ 0.05.

Article Snippet: Sucrose preference curves were collected using a commercially available gustometer (Med Associates Inc., Davis Rig for Mouse-16 Bottle).

Techniques: Sequencing, Two Tailed Test, Modification, MANN-WHITNEY

Journal: Physiology & behavior

Article Title: Altered salt taste response and increased tongue epithelium Scnna1 expression in adult Engrailed-2 null mice

doi: 10.1016/j.physbeh.2018.06.030

Figure Lengend Snippet: Data were collected using an automated gustometer. A single trial with an individual concentration began with an opened shutter and 5 sec access to the drinking spout. The intertrial interval was 8 secs. There was a maximum of 105 spout-exposures trials for each taste stimulus. The mean number of licks for each concentration for each mouse is the mean value for 15 trials. Water is 0M on the x-axis. The taste responsivity for A: sucrose, B: fructose, C: sodium chloride, D: monosodium glutamate, E: alanine, F: citric acid, and G: quinine in En2 +/+ (WT; closed squares, n = 7) and En2 −/− (KO; open circles, n = 16) mice. * indicates p < 0.05 post-hoc testing differences from WT for an individual concentration. # indicates p < 0.05 planned comparison testing differences from WT for an individual concentration.

Article Snippet: An automated gustometer (Davis Rig; Dilog Instruments, Tallahassee, Florida) was used to measure the number of licks for the different concentrations of taste stimuli for each animal [ 24 ] [ 26 ] [ 27 ].

Techniques: Concentration Assay, Comparison

Journal: Laryngoscope Investigative Otolaryngology

Article Title: Systematic review: Validity, reliability, and diagnostic accuracy of the electrogustometer

doi: 10.1002/lio2.1108

Figure Lengend Snippet: Characteristics of the included studies.

Article Snippet: Nilsson (1977) , Prospective cohort study , Sweden , 31 (61) , 25 (NR) , Healthy , Madson GO 70 gustometer, Madsen Electronics, Copenhagen, Denmark , Ascending and descending protocol , CT , 1000–1500 , NA , Reliability (test–retest).

Techniques: Construct, Diagnostic Assay