93
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MedChemExpress
gmb 475 Gmb 475, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/gmb-475/GMB-475/pmc09924227__5fqnGflPOhEo0ZeBMI1oVMdhXUFj7tk2lWWrA7dpGoYti3pd1PT2dNdjovdJPtgnDmZjNeaqFIoKSTrPhOuyAXZOzKdtL-120-3-13 Average 93 stars, based on 1 article reviews
gmb 475 - by Bioz Stars,
2026-10
93/100 stars
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GMB-475（Cat No.:I028167） is a compound that functions as a degrader of BCR-ABL1 tyrosine kinase, utilizing the PROTAC (proteolysis-targeting chimera) approach. It effectively addresses drug resistance associated with BCR-ABL1-dependent malignancies. GMB-475 selectively targets the BCR-ABL1 protein
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90
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CH Instruments
gmb-475 Gmb 475, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/gmb-475/gmb+475/pmc06893872-161-42-92 Average 90 stars, based on 1 article reviews
gmb-475 - by Bioz Stars,
2026-10
90/100 stars
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GMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1 protein and recruit the E3 ligase Von Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.
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InformationGMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1 protein and recruit the E3 ligase Von Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.TargetsBCR-ABL1 ; E3 ligaseIn vitroGMB-475 induces
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