glycoprotein Search Results


anti sortilin  (Alomone Labs)
93
Alomone Labs anti sortilin
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Anti Sortilin, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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fucose  (Vector Laboratories)
93
Vector Laboratories fucose
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Fucose, supplied by Vector Laboratories, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human lrg1 ab  (Assaypro)
90
Assaypro human lrg1 ab
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Human Lrg1 Ab, supplied by Assaypro, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hpx  (Athens Research)
95
Athens Research hpx
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Hpx, supplied by Athens Research, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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h08y human il 8 mce cat  (MedChemExpress)
93
MedChemExpress h08y human il 8 mce cat
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
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mog 35 55  (MedChemExpress)
93
MedChemExpress mog 35 55
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Mog 35 55, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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partial human novel coronavirus spike glycoprotein  (Cusabio)
90
Cusabio partial human novel coronavirus spike glycoprotein
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Partial Human Novel Coronavirus Spike Glycoprotein, supplied by Cusabio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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recombinant human novel coronavirus spike glycoprotein  (Cusabio)
92
Cusabio recombinant human novel coronavirus spike glycoprotein
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Recombinant Human Novel Coronavirus Spike Glycoprotein, supplied by Cusabio, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human coronavirus nl63  (Native Antigen Inc)
92
Native Antigen Inc human coronavirus nl63
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Human Coronavirus Nl63, supplied by Native Antigen Inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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sars cov 2 spike s1  (Native Antigen Inc)
93
Native Antigen Inc sars cov 2 spike s1
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Sars Cov 2 Spike S1, supplied by Native Antigen Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rec31868 500  (Native Antigen Inc)
94
Native Antigen Inc rec31868 500
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Rec31868 500, supplied by Native Antigen Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rec31806 sars cov 2 spike glycoprotein s1  (Native Antigen Inc)
93
Native Antigen Inc rec31806 sars cov 2 spike glycoprotein s1
<t>Sortilin</t> protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed <t>by</t> <t>immunohistochemistry</t> (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods
Rec31806 Sars Cov 2 Spike Glycoprotein S1, supplied by Native Antigen Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Sortilin protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed by immunohistochemistry (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods

Journal: Journal of Cellular and Molecular Medicine

Article Title: Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cancer

doi: 10.1111/jcmm.15752

Figure Lengend Snippet: Sortilin protein expression increases upon 5‐FU treatment in tumours from Nude mice xenografted with CRC cell lines. A, Tumour volume of WiDr and SW620 xenografted Nude mice untreated (CTL) or exposed to 5‐FU (5‐FU) was determined every 3 days from the graft and during the treatment protocol, as described in material and methods ( V = [L × W(L + W)]ᴨ/12). T. I. refers to Treatment Initiation. B, Sortilin protein expression analysis by Western blotting on whole lysates obtained from tumours of untreated xenografted Nude mice and 5‐FU‐treated ones ( n = 5 per conditions). Actin was used as loading control. Histograms represent means of 5 different samples (significant P ‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001). C, Representative illustration of sortilin protein expression observed by immunohistochemistry (magnification x100) on paraffin‐embedded xenografted Nude mice tumours ( n = 5 per conditions). Histograms represent the immunochemistry intensity score, as described in material and methods

Article Snippet: For immunohistochemistry analysis, primary antibody used was mouse anti‐sortilin (ANT‐016, Alomone Labs).

Techniques: Expressing, Western Blot, Immunohistochemistry

High SORT1 expression is associated with poorer survival, DFS and RFS, and sortilin expression is associated with higher CRC tumour grades. SORT1 expression levels by risk group according to survival ( n = 77; A), DFS ( n = 545; B) and RFS ( n = 37; C) of patients suffering from CRC, extracted from ‘SurvExpress’ database. Significant P‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001. D, Sortilin protein expression, observed by immunohistochemistry (magnification, 50×) on tissue microarrays including seven samples of benign tissue and 126 samples from CRC tumours of different grades ( n = 8, 98, and 20 for grades I, II and III, respectively). Quantification was performed by calculating the immunochemistry intensity score described in materials and methods. E, Sortilin expression in whole‐cell lysates of WiDr and SW620. Actin was used as a loading control

Journal: Journal of Cellular and Molecular Medicine

Article Title: Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cancer

doi: 10.1111/jcmm.15752

Figure Lengend Snippet: High SORT1 expression is associated with poorer survival, DFS and RFS, and sortilin expression is associated with higher CRC tumour grades. SORT1 expression levels by risk group according to survival ( n = 77; A), DFS ( n = 545; B) and RFS ( n = 37; C) of patients suffering from CRC, extracted from ‘SurvExpress’ database. Significant P‐values are indicated in the graphs * P < .05, ** P < .01, *** P < .001. D, Sortilin protein expression, observed by immunohistochemistry (magnification, 50×) on tissue microarrays including seven samples of benign tissue and 126 samples from CRC tumours of different grades ( n = 8, 98, and 20 for grades I, II and III, respectively). Quantification was performed by calculating the immunochemistry intensity score described in materials and methods. E, Sortilin expression in whole‐cell lysates of WiDr and SW620. Actin was used as a loading control

Article Snippet: For immunohistochemistry analysis, primary antibody used was mouse anti‐sortilin (ANT‐016, Alomone Labs).

Techniques: Expressing, Immunohistochemistry