fliplr function Search Results


94
Danaher Inc flipr flipr
Concentration effect curves to senktide (n=5), [MePhe7]-NKB (n=5), NKB (n=4), NKA (n=4) and SP (n=4) in CHO-K1 cells transiently expressing the rabbit NK3 receptor. Increases <t>in</t> <t>intracellular</t> calcium induced by each agonist were measured using <t>FLIPR.</t> Results are expressed as a percentage of the maximum response and data are mean with vertical lines showing s.e.mean.
Flipr Flipr, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/flipr flipr/product/Danaher Inc
Average 94 stars, based on 1 article reviews
flipr flipr - by Bioz Stars, 2026-05
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90
Merck KGaA ccr2 chemiscreentm ccr2b calcium-optimized flipr cell line
Concentration effect curves to senktide (n=5), [MePhe7]-NKB (n=5), NKB (n=4), NKA (n=4) and SP (n=4) in CHO-K1 cells transiently expressing the rabbit NK3 receptor. Increases <t>in</t> <t>intracellular</t> calcium induced by each agonist were measured using <t>FLIPR.</t> Results are expressed as a percentage of the maximum response and data are mean with vertical lines showing s.e.mean.
Ccr2 Chemiscreentm Ccr2b Calcium Optimized Flipr Cell Line, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ccr2 chemiscreentm ccr2b calcium-optimized flipr cell line/product/Merck KGaA
Average 90 stars, based on 1 article reviews
ccr2 chemiscreentm ccr2b calcium-optimized flipr cell line - by Bioz Stars, 2026-05
90/100 stars
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Concentration effect curves to senktide (n=5), [MePhe7]-NKB (n=5), NKB (n=4), NKA (n=4) and SP (n=4) in CHO-K1 cells transiently expressing the rabbit NK3 receptor. Increases in intracellular calcium induced by each agonist were measured using FLIPR. Results are expressed as a percentage of the maximum response and data are mean with vertical lines showing s.e.mean.

Journal:

Article Title: Molecular and pharmacological characterization of a functional tachykinin NK 3 receptor cloned from the rabbit iris sphincter muscle

doi: 10.1038/sj.bjp.0702854

Figure Lengend Snippet: Concentration effect curves to senktide (n=5), [MePhe7]-NKB (n=5), NKB (n=4), NKA (n=4) and SP (n=4) in CHO-K1 cells transiently expressing the rabbit NK3 receptor. Increases in intracellular calcium induced by each agonist were measured using FLIPR. Results are expressed as a percentage of the maximum response and data are mean with vertical lines showing s.e.mean.

Article Snippet: The concentration of drug inhibiting specific [ 125 I]-[MePhe 7 ]-NKB binding by 50% (IC 50 ) was determined by iterative curve fitting ( Bowen & Jerman, 1995 ). pK i values (−log of the inhibition constant) for receptor binding were then calculated from the IC 50 values as described by Cheng & Prusoff (1973) using a K d value of 0.3 n M . Measurement of intracellular calcium using FLIPR FLIPR (Fluorescent Imaging Plate Reader, Molecular Devices; Schroeder & Neagle, 1996 ) assays measuring changes in intracellular calcium were carried out to assess functional activity of NK 3 receptor agonists and antagonists at the rabbit NK 3 receptor.

Techniques: Concentration Assay, Expressing