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Image Search Results
Journal: PLoS ONE
Article Title: Deregulation of Mitochondria-Shaping Proteins Opa-1 and Drp-1 in Manganese-Induced Apoptosis
doi: 10.1371/journal.pone.0091848
Figure Lengend Snippet: Mitochondria were visualized with MitoTracker Red CMXRos (75 nM) under a fluorescence microscope. Representative images acquired and deconvoluted are shown . Scale bar: 10 µm. Three categories of cells exhibiting different mitochondrial morphology were scored: tubular mitochondria (normal), intermediate mitochondria (filamentous with swelling regions) and fragmented (globular). Cells classified as “loss of Δψm” refers to those exhibiting nuclear condensation and Δψm collapse ( A ); 200 cells/sample were counted and classified according to item A ( B ). Two independent experiments were conducted. Statistical significance, ***p<0.001 vs. control and ##p<0.01 vs. Mn.
Article Snippet: Samples were examined under a
Techniques: Fluorescence, Microscopy, Control