dy1599 Search Results


human micb duoset elisa kit  (R&D Systems)
93
R&D Systems human micb duoset elisa kit
Figure 1. 3MICA/B CAR targets the conserved alpha-3 domains of MICA/B stress ligands and is resistant to binding competition by shed MICA/B A novel MICA/B-targeting synthetic receptor capable of high-affinity pan-allelic binding, surface MICA/B density augmentation, and resistance to inhibition via shed MICA and <t>MICB</t> peptides. (A) Domain-specific amino acid sequence similarity was scored across the 21 most prevalent MICA and MICB alleles using the BLOSUM method highlighting greater sequence conservation within the membrane-proximal a3 domain relative to the membrane-distal a1-2 domains. (B) Pan-allelic reactivity of 3MICA/B mAb, an a1-2 MICA/B-reactive mAb (6D4), and NKG2D:Fc fusion protein was assessed across an extended panel of 28 prevalent MICA alleles. (C) MM1-R cells, pre-treated with trypsin to cleave baseline surface-expressed MICA/B ligands, were incubated with 3MICA/B mAb, or relevant isotype, and surface MICA/B expression kinetics was measured using a commercial mAb (6D4) over a 96-h time course. In parallel, MM1.R cells were incubated
Human Micb Duoset Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dy1599/pm37172578-401-15-21?v=R%26D+Systems
Average 93 stars, based on 1 article reviews
human micb duoset elisa kit - by Bioz Stars, 2026-06
93/100 stars
  Buy from Supplier
human micb duoset sandwich elisa kit  (R&D Systems)
94
R&D Systems human micb duoset sandwich elisa kit
Figure 1. 3MICA/B CAR targets the conserved alpha-3 domains of MICA/B stress ligands and is resistant to binding competition by shed MICA/B A novel MICA/B-targeting synthetic receptor capable of high-affinity pan-allelic binding, surface MICA/B density augmentation, and resistance to inhibition via shed MICA and <t>MICB</t> peptides. (A) Domain-specific amino acid sequence similarity was scored across the 21 most prevalent MICA and MICB alleles using the BLOSUM method highlighting greater sequence conservation within the membrane-proximal a3 domain relative to the membrane-distal a1-2 domains. (B) Pan-allelic reactivity of 3MICA/B mAb, an a1-2 MICA/B-reactive mAb (6D4), and NKG2D:Fc fusion protein was assessed across an extended panel of 28 prevalent MICA alleles. (C) MM1-R cells, pre-treated with trypsin to cleave baseline surface-expressed MICA/B ligands, were incubated with 3MICA/B mAb, or relevant isotype, and surface MICA/B expression kinetics was measured using a commercial mAb (6D4) over a 96-h time course. In parallel, MM1.R cells were incubated
Human Micb Duoset Sandwich Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dy1599/pmc03784540-339-10-16?v=R%26D+Systems
Average 94 stars, based on 1 article reviews
human micb duoset sandwich elisa kit - by Bioz Stars, 2026-06
94/100 stars
  Buy from Supplier

Image Search Results


Figure 1. 3MICA/B CAR targets the conserved alpha-3 domains of MICA/B stress ligands and is resistant to binding competition by shed MICA/B A novel MICA/B-targeting synthetic receptor capable of high-affinity pan-allelic binding, surface MICA/B density augmentation, and resistance to inhibition via shed MICA and MICB peptides. (A) Domain-specific amino acid sequence similarity was scored across the 21 most prevalent MICA and MICB alleles using the BLOSUM method highlighting greater sequence conservation within the membrane-proximal a3 domain relative to the membrane-distal a1-2 domains. (B) Pan-allelic reactivity of 3MICA/B mAb, an a1-2 MICA/B-reactive mAb (6D4), and NKG2D:Fc fusion protein was assessed across an extended panel of 28 prevalent MICA alleles. (C) MM1-R cells, pre-treated with trypsin to cleave baseline surface-expressed MICA/B ligands, were incubated with 3MICA/B mAb, or relevant isotype, and surface MICA/B expression kinetics was measured using a commercial mAb (6D4) over a 96-h time course. In parallel, MM1.R cells were incubated

Journal: Med (New York, N.Y.)

Article Title: A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors.

doi: 10.1016/j.medj.2023.04.004

Figure Lengend Snippet: Figure 1. 3MICA/B CAR targets the conserved alpha-3 domains of MICA/B stress ligands and is resistant to binding competition by shed MICA/B A novel MICA/B-targeting synthetic receptor capable of high-affinity pan-allelic binding, surface MICA/B density augmentation, and resistance to inhibition via shed MICA and MICB peptides. (A) Domain-specific amino acid sequence similarity was scored across the 21 most prevalent MICA and MICB alleles using the BLOSUM method highlighting greater sequence conservation within the membrane-proximal a3 domain relative to the membrane-distal a1-2 domains. (B) Pan-allelic reactivity of 3MICA/B mAb, an a1-2 MICA/B-reactive mAb (6D4), and NKG2D:Fc fusion protein was assessed across an extended panel of 28 prevalent MICA alleles. (C) MM1-R cells, pre-treated with trypsin to cleave baseline surface-expressed MICA/B ligands, were incubated with 3MICA/B mAb, or relevant isotype, and surface MICA/B expression kinetics was measured using a commercial mAb (6D4) over a 96-h time course. In parallel, MM1.R cells were incubated

Article Snippet: The concentration of shed MICA/B was measured using a human MICA ELISA (Ab59569, Abcam) or human MICB DuoSet ELISA kit (DY1599, R&D Systems), following the manufacture’s recommendation.

Techniques: Binding Assay, Inhibition, Sequencing, Membrane, Incubation, Expressing