dox fluorescence Search Results


90
AIEgen Biotech Co Ltd self-fluorescent dox-loaded hnps with unique aiegen characteristic
Self Fluorescent Dox Loaded Hnps With Unique Aiegen Characteristic, supplied by AIEgen Biotech Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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CEM Corporation doxorubicin fluorescence
Dose–response curve for the nine selected compounds. ( A ) bidwillon A; ( B ) neobavaisoflavone; ( C ) coptisine chloride; ( D ) chamazulene; ( E ) <t>miltirone;</t> ( F ) z-guggulsterone. Shown are the dose–response curves of wildtype drug-sensitive CCRF-CEM cells and their P-gp-overexpressing multidrug-resistant subline CEM/ADR5000. Mean values ± SD of three independent experiments, each with six parallel measurements, are presented.
Doxorubicin Fluorescence, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dox+fluorescence/doxorubicin+fluorescence++dox+/pmc10299530-91-17-7
Average 90 stars, based on 1 article reviews
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CEM Corporation dox fluorescence
Dose–response curve for the nine selected compounds. ( A ) bidwillon A; ( B ) neobavaisoflavone; ( C ) coptisine chloride; ( D ) chamazulene; ( E ) <t>miltirone;</t> ( F ) z-guggulsterone. Shown are the dose–response curves of wildtype drug-sensitive CCRF-CEM cells and their P-gp-overexpressing multidrug-resistant subline CEM/ADR5000. Mean values ± SD of three independent experiments, each with six parallel measurements, are presented.
Dox Fluorescence, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dox+fluorescence/dox+fluorescence/pmc03891927-98-3-12
Average 90 stars, based on 1 article reviews
dox fluorescence - by Bioz Stars, 2026-10
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Verlag GmbH dox fluorescence
Dose–response curve for the nine selected compounds. ( A ) bidwillon A; ( B ) neobavaisoflavone; ( C ) coptisine chloride; ( D ) chamazulene; ( E ) <t>miltirone;</t> ( F ) z-guggulsterone. Shown are the dose–response curves of wildtype drug-sensitive CCRF-CEM cells and their P-gp-overexpressing multidrug-resistant subline CEM/ADR5000. Mean values ± SD of three independent experiments, each with six parallel measurements, are presented.
Dox Fluorescence, supplied by Verlag GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dox+fluorescence/dox+fluorescence/pm30328157-84-18-5
Average 90 stars, based on 1 article reviews
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CEM Corporation fluorescent dox metabolites
Dose–response curve for the nine selected compounds. ( A ) bidwillon A; ( B ) neobavaisoflavone; ( C ) coptisine chloride; ( D ) chamazulene; ( E ) <t>miltirone;</t> ( F ) z-guggulsterone. Shown are the dose–response curves of wildtype drug-sensitive CCRF-CEM cells and their P-gp-overexpressing multidrug-resistant subline CEM/ADR5000. Mean values ± SD of three independent experiments, each with six parallel measurements, are presented.
Fluorescent Dox Metabolites, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dox+fluorescence/fluorescent+dox+metabolites/pm15261824-133-7-22
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CEM Corporation dox fluorescence intensity
Dose–response curve for the nine selected compounds. ( A ) bidwillon A; ( B ) neobavaisoflavone; ( C ) coptisine chloride; ( D ) chamazulene; ( E ) <t>miltirone;</t> ( F ) z-guggulsterone. Shown are the dose–response curves of wildtype drug-sensitive CCRF-CEM cells and their P-gp-overexpressing multidrug-resistant subline CEM/ADR5000. Mean values ± SD of three independent experiments, each with six parallel measurements, are presented.
Dox Fluorescence Intensity, supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dox+fluorescence/dox+fluorescence+intensity/pm35025450-124-82-86
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Image Search Results


Dose–response curve for the nine selected compounds. ( A ) bidwillon A; ( B ) neobavaisoflavone; ( C ) coptisine chloride; ( D ) chamazulene; ( E ) miltirone; ( F ) z-guggulsterone. Shown are the dose–response curves of wildtype drug-sensitive CCRF-CEM cells and their P-gp-overexpressing multidrug-resistant subline CEM/ADR5000. Mean values ± SD of three independent experiments, each with six parallel measurements, are presented.

Journal: International Journal of Molecular Sciences

Article Title: In Silico and In Vitro Identification of P-Glycoprotein Inhibitors from a Library of 375 Phytochemicals

doi: 10.3390/ijms241210240

Figure Lengend Snippet: Dose–response curve for the nine selected compounds. ( A ) bidwillon A; ( B ) neobavaisoflavone; ( C ) coptisine chloride; ( D ) chamazulene; ( E ) miltirone; ( F ) z-guggulsterone. Shown are the dose–response curves of wildtype drug-sensitive CCRF-CEM cells and their P-gp-overexpressing multidrug-resistant subline CEM/ADR5000. Mean values ± SD of three independent experiments, each with six parallel measurements, are presented.

Article Snippet: D,E show the increased doxorubicin fluorescence in CEM/ADR5000 cells treated with doxorubicin in combination with chamazulene or miltirone.

Techniques:

Selection of six candidate compounds based on their interaction with P-gp (as determined by AutoDock and PyRx) and their structural alignment with known P-gp inhibitors (as determined by Torch3D). Scores > 0.5 were labeled in bold.

Journal: International Journal of Molecular Sciences

Article Title: In Silico and In Vitro Identification of P-Glycoprotein Inhibitors from a Library of 375 Phytochemicals

doi: 10.3390/ijms241210240

Figure Lengend Snippet: Selection of six candidate compounds based on their interaction with P-gp (as determined by AutoDock and PyRx) and their structural alignment with known P-gp inhibitors (as determined by Torch3D). Scores > 0.5 were labeled in bold.

Article Snippet: D,E show the increased doxorubicin fluorescence in CEM/ADR5000 cells treated with doxorubicin in combination with chamazulene or miltirone.

Techniques: Selection, Labeling

Flow cytometric analysis of doxorubicin uptake by P-gp-overexpressing CEM/ADR5000 cells with and without coincubation of six phytochemical candidate compounds. The bar diagrams represent mean fluorescence intensity values of CEM/ADR5000 cells as percentages of the fluorescence in CCRF-CEM control cells. The bars show mean values ± SD of three independent experiments. ( A ) bidwillon A; ( B ) neobavaisoflavone; ( C ) coptisine chloride; ( D ) chamazulene; ( E ) miltirone; and ( F ) z-guggulsterone. * p < 0.05.

Journal: International Journal of Molecular Sciences

Article Title: In Silico and In Vitro Identification of P-Glycoprotein Inhibitors from a Library of 375 Phytochemicals

doi: 10.3390/ijms241210240

Figure Lengend Snippet: Flow cytometric analysis of doxorubicin uptake by P-gp-overexpressing CEM/ADR5000 cells with and without coincubation of six phytochemical candidate compounds. The bar diagrams represent mean fluorescence intensity values of CEM/ADR5000 cells as percentages of the fluorescence in CCRF-CEM control cells. The bars show mean values ± SD of three independent experiments. ( A ) bidwillon A; ( B ) neobavaisoflavone; ( C ) coptisine chloride; ( D ) chamazulene; ( E ) miltirone; and ( F ) z-guggulsterone. * p < 0.05.

Article Snippet: D,E show the increased doxorubicin fluorescence in CEM/ADR5000 cells treated with doxorubicin in combination with chamazulene or miltirone.

Techniques: Fluorescence, Control

Molecular docking of bidwillon A and miltirone in relation to wildtype and mutated P-gp forms. ( A ) Missense mutations in the transmembrane domains of P-gp. ( B ) Molecular docking (defined mode) of bidwillon A and miltirone in relation to single, double, and quadruple P-gp mutants. Tariquidar and doxorubicin served as control drugs as the known inhibitor and the substrate, respectively. ( C ) Linear regressions of all binding energies and predicted inhibition constant (pKi) values in closed and open P-gp conformations ( r > 0.9).

Journal: International Journal of Molecular Sciences

Article Title: In Silico and In Vitro Identification of P-Glycoprotein Inhibitors from a Library of 375 Phytochemicals

doi: 10.3390/ijms241210240

Figure Lengend Snippet: Molecular docking of bidwillon A and miltirone in relation to wildtype and mutated P-gp forms. ( A ) Missense mutations in the transmembrane domains of P-gp. ( B ) Molecular docking (defined mode) of bidwillon A and miltirone in relation to single, double, and quadruple P-gp mutants. Tariquidar and doxorubicin served as control drugs as the known inhibitor and the substrate, respectively. ( C ) Linear regressions of all binding energies and predicted inhibition constant (pKi) values in closed and open P-gp conformations ( r > 0.9).

Article Snippet: D,E show the increased doxorubicin fluorescence in CEM/ADR5000 cells treated with doxorubicin in combination with chamazulene or miltirone.

Techniques: Control, Binding Assay, Inhibition