double gradient heatmap plot Search Results


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Nuclear metabolic activity is altered due to KIC5 disruption. We identified several similarities between the transcriptome of the K13 mutant, associated with altered DNA replication and repair expression, and the KIC5 mutant. ( a ) Correlation of the NF54 (left) and KIC5 mutant (right) datasets from this study to the WT and K13 mutant datasets from Gibbons et al. (Supplementary Fig. ). <t>Heatmaps</t> made in R Studio using the pheatmap function and dataset correlation shown via Spearman correlation (Spearman correlation values available in Supplementary Table ). Gene ontology enrichment analysis of KIC5 mutant expression across the IDC identified differential expression of genes associated with nuclear compartment (GO:0005634) (Supplementary Table ). Log2-fold change (KIC5 mutant/NF54) analysis via violin plot ( b ) and FPKM analysis of expression in WT (top panel) and mutant (bottom panel) ( c ) shows dysregulation of these genes associated with nuclear compartment GO at 6 hpi, 12 hpi, and 24 hpi. ( d ) Molecular function GO enrichment of nuclear compartment (GO:0005634) genes in the KIC5 mutant. Log2-fold change of genes located in the K13 endocytosis complex shows a similar differential expression to nuclear compartment associated genes, further supporting the link between KIC5, K13, and the K13 complex with altered DNA replication and repair associated pathways (Supplementary Table ). Log2-fold change data shown for the KIC5 mutant compared to WT expression and graphed on GraphPad Prism 9.
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Nuclear metabolic activity is altered due to KIC5 disruption. We identified several similarities between the transcriptome of the K13 mutant, associated with altered DNA replication and repair expression, and the KIC5 mutant. ( a ) Correlation of the NF54 (left) and KIC5 mutant (right) datasets from this study to the WT and K13 mutant datasets from Gibbons et al. (Supplementary Fig. ). <t>Heatmaps</t> made in R Studio using the pheatmap function and dataset correlation shown via Spearman correlation (Spearman correlation values available in Supplementary Table ). Gene ontology enrichment analysis of KIC5 mutant expression across the IDC identified differential expression of genes associated with nuclear compartment (GO:0005634) (Supplementary Table ). Log2-fold change (KIC5 mutant/NF54) analysis via violin plot ( b ) and FPKM analysis of expression in WT (top panel) and mutant (bottom panel) ( c ) shows dysregulation of these genes associated with nuclear compartment GO at 6 hpi, 12 hpi, and 24 hpi. ( d ) Molecular function GO enrichment of nuclear compartment (GO:0005634) genes in the KIC5 mutant. Log2-fold change of genes located in the K13 endocytosis complex shows a similar differential expression to nuclear compartment associated genes, further supporting the link between KIC5, K13, and the K13 complex with altered DNA replication and repair associated pathways (Supplementary Table ). Log2-fold change data shown for the KIC5 mutant compared to WT expression and graphed on GraphPad Prism 9.
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Nuclear metabolic activity is altered due to KIC5 disruption. We identified several similarities between the transcriptome of the K13 mutant, associated with altered DNA replication and repair expression, and the KIC5 mutant. ( a ) Correlation of the NF54 (left) and KIC5 mutant (right) datasets from this study to the WT and K13 mutant datasets from Gibbons et al. (Supplementary Fig. ). <t>Heatmaps</t> made in R Studio using the pheatmap function and dataset correlation shown via Spearman correlation (Spearman correlation values available in Supplementary Table ). Gene ontology enrichment analysis of KIC5 mutant expression across the IDC identified differential expression of genes associated with nuclear compartment (GO:0005634) (Supplementary Table ). Log2-fold change (KIC5 mutant/NF54) analysis via violin plot ( b ) and FPKM analysis of expression in WT (top panel) and mutant (bottom panel) ( c ) shows dysregulation of these genes associated with nuclear compartment GO at 6 hpi, 12 hpi, and 24 hpi. ( d ) Molecular function GO enrichment of nuclear compartment (GO:0005634) genes in the KIC5 mutant. Log2-fold change of genes located in the K13 endocytosis complex shows a similar differential expression to nuclear compartment associated genes, further supporting the link between KIC5, K13, and the K13 complex with altered DNA replication and repair associated pathways (Supplementary Table ). Log2-fold change data shown for the KIC5 mutant compared to WT expression and graphed on GraphPad Prism 9.
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Nuclear metabolic activity is altered due to KIC5 disruption. We identified several similarities between the transcriptome of the K13 mutant, associated with altered DNA replication and repair expression, and the KIC5 mutant. ( a ) Correlation of the NF54 (left) and KIC5 mutant (right) datasets from this study to the WT and K13 mutant datasets from Gibbons et al. (Supplementary Fig. ). <t>Heatmaps</t> made in R Studio using the pheatmap function and dataset correlation shown via Spearman correlation (Spearman correlation values available in Supplementary Table ). Gene ontology enrichment analysis of KIC5 mutant expression across the IDC identified differential expression of genes associated with nuclear compartment (GO:0005634) (Supplementary Table ). Log2-fold change (KIC5 mutant/NF54) analysis via violin plot ( b ) and FPKM analysis of expression in WT (top panel) and mutant (bottom panel) ( c ) shows dysregulation of these genes associated with nuclear compartment GO at 6 hpi, 12 hpi, and 24 hpi. ( d ) Molecular function GO enrichment of nuclear compartment (GO:0005634) genes in the KIC5 mutant. Log2-fold change of genes located in the K13 endocytosis complex shows a similar differential expression to nuclear compartment associated genes, further supporting the link between KIC5, K13, and the K13 complex with altered DNA replication and repair associated pathways (Supplementary Table ). Log2-fold change data shown for the KIC5 mutant compared to WT expression and graphed on GraphPad Prism 9.
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Nuclear metabolic activity is altered due to KIC5 disruption. We identified several similarities between the transcriptome of the K13 mutant, associated with altered DNA replication and repair expression, and the KIC5 mutant. ( a ) Correlation of the NF54 (left) and KIC5 mutant (right) datasets from this study to the WT and K13 mutant datasets from Gibbons et al. (Supplementary Fig. ). <t>Heatmaps</t> made in R Studio using the pheatmap function and dataset correlation shown via Spearman correlation (Spearman correlation values available in Supplementary Table ). Gene ontology enrichment analysis of KIC5 mutant expression across the IDC identified differential expression of genes associated with nuclear compartment (GO:0005634) (Supplementary Table ). Log2-fold change (KIC5 mutant/NF54) analysis via violin plot ( b ) and FPKM analysis of expression in WT (top panel) and mutant (bottom panel) ( c ) shows dysregulation of these genes associated with nuclear compartment GO at 6 hpi, 12 hpi, and 24 hpi. ( d ) Molecular function GO enrichment of nuclear compartment (GO:0005634) genes in the KIC5 mutant. Log2-fold change of genes located in the K13 endocytosis complex shows a similar differential expression to nuclear compartment associated genes, further supporting the link between KIC5, K13, and the K13 complex with altered DNA replication and repair associated pathways (Supplementary Table ). Log2-fold change data shown for the KIC5 mutant compared to WT expression and graphed on GraphPad Prism 9.
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Novogene heatmaps
Nuclear metabolic activity is altered due to KIC5 disruption. We identified several similarities between the transcriptome of the K13 mutant, associated with altered DNA replication and repair expression, and the KIC5 mutant. ( a ) Correlation of the NF54 (left) and KIC5 mutant (right) datasets from this study to the WT and K13 mutant datasets from Gibbons et al. (Supplementary Fig. ). <t>Heatmaps</t> made in R Studio using the pheatmap function and dataset correlation shown via Spearman correlation (Spearman correlation values available in Supplementary Table ). Gene ontology enrichment analysis of KIC5 mutant expression across the IDC identified differential expression of genes associated with nuclear compartment (GO:0005634) (Supplementary Table ). Log2-fold change (KIC5 mutant/NF54) analysis via violin plot ( b ) and FPKM analysis of expression in WT (top panel) and mutant (bottom panel) ( c ) shows dysregulation of these genes associated with nuclear compartment GO at 6 hpi, 12 hpi, and 24 hpi. ( d ) Molecular function GO enrichment of nuclear compartment (GO:0005634) genes in the KIC5 mutant. Log2-fold change of genes located in the K13 endocytosis complex shows a similar differential expression to nuclear compartment associated genes, further supporting the link between KIC5, K13, and the K13 complex with altered DNA replication and repair associated pathways (Supplementary Table ). Log2-fold change data shown for the KIC5 mutant compared to WT expression and graphed on GraphPad Prism 9.
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Strava Inc strava global heatmap
Research questions that compare data from traditional and application-based tools.
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Research questions that compare data from traditional and application-based tools.
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Image Search Results


Nuclear metabolic activity is altered due to KIC5 disruption. We identified several similarities between the transcriptome of the K13 mutant, associated with altered DNA replication and repair expression, and the KIC5 mutant. ( a ) Correlation of the NF54 (left) and KIC5 mutant (right) datasets from this study to the WT and K13 mutant datasets from Gibbons et al. (Supplementary Fig. ). Heatmaps made in R Studio using the pheatmap function and dataset correlation shown via Spearman correlation (Spearman correlation values available in Supplementary Table ). Gene ontology enrichment analysis of KIC5 mutant expression across the IDC identified differential expression of genes associated with nuclear compartment (GO:0005634) (Supplementary Table ). Log2-fold change (KIC5 mutant/NF54) analysis via violin plot ( b ) and FPKM analysis of expression in WT (top panel) and mutant (bottom panel) ( c ) shows dysregulation of these genes associated with nuclear compartment GO at 6 hpi, 12 hpi, and 24 hpi. ( d ) Molecular function GO enrichment of nuclear compartment (GO:0005634) genes in the KIC5 mutant. Log2-fold change of genes located in the K13 endocytosis complex shows a similar differential expression to nuclear compartment associated genes, further supporting the link between KIC5, K13, and the K13 complex with altered DNA replication and repair associated pathways (Supplementary Table ). Log2-fold change data shown for the KIC5 mutant compared to WT expression and graphed on GraphPad Prism 9.

Journal: Scientific Reports

Article Title: Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum

doi: 10.1038/s41598-023-27417-6

Figure Lengend Snippet: Nuclear metabolic activity is altered due to KIC5 disruption. We identified several similarities between the transcriptome of the K13 mutant, associated with altered DNA replication and repair expression, and the KIC5 mutant. ( a ) Correlation of the NF54 (left) and KIC5 mutant (right) datasets from this study to the WT and K13 mutant datasets from Gibbons et al. (Supplementary Fig. ). Heatmaps made in R Studio using the pheatmap function and dataset correlation shown via Spearman correlation (Spearman correlation values available in Supplementary Table ). Gene ontology enrichment analysis of KIC5 mutant expression across the IDC identified differential expression of genes associated with nuclear compartment (GO:0005634) (Supplementary Table ). Log2-fold change (KIC5 mutant/NF54) analysis via violin plot ( b ) and FPKM analysis of expression in WT (top panel) and mutant (bottom panel) ( c ) shows dysregulation of these genes associated with nuclear compartment GO at 6 hpi, 12 hpi, and 24 hpi. ( d ) Molecular function GO enrichment of nuclear compartment (GO:0005634) genes in the KIC5 mutant. Log2-fold change of genes located in the K13 endocytosis complex shows a similar differential expression to nuclear compartment associated genes, further supporting the link between KIC5, K13, and the K13 complex with altered DNA replication and repair associated pathways (Supplementary Table ). Log2-fold change data shown for the KIC5 mutant compared to WT expression and graphed on GraphPad Prism 9.

Article Snippet: Heatmaps made in R Studio using the pheatmap function and dataset correlation shown via Spearman correlation (Spearman correlation values available in Supplementary Table ).

Techniques: Activity Assay, Disruption, Mutagenesis, Expressing, Quantitative Proteomics

Research questions that compare data from traditional and application-based tools.

Journal: PeerJ

Article Title: Advancements in monitoring: a comparison of traditional and application-based tools for measuring outdoor recreation

doi: 10.7717/peerj.17744

Figure Lengend Snippet: Research questions that compare data from traditional and application-based tools.

Article Snippet: Strava Global Heatmap – Strava Global Heatmap (hereafter, Strava Heatmap; https://www.strava.com/heatmap) is a crowdsourced heatmap that uses GPS-based recreation tracks of public non-motorized recreation activities (run, hike, walk, ride, water, winter) recorded on phones, fitness watches, and GPS devices.

Techniques:

Strava Heatmap not displayed (see ). Base map sources: ©OpenStreetMap and contributors, CC-BY-SA.

Journal: PeerJ

Article Title: Advancements in monitoring: a comparison of traditional and application-based tools for measuring outdoor recreation

doi: 10.7717/peerj.17744

Figure Lengend Snippet: Strava Heatmap not displayed (see ). Base map sources: ©OpenStreetMap and contributors, CC-BY-SA.

Article Snippet: Strava Global Heatmap – Strava Global Heatmap (hereafter, Strava Heatmap; https://www.strava.com/heatmap) is a crowdsourced heatmap that uses GPS-based recreation tracks of public non-motorized recreation activities (run, hike, walk, ride, water, winter) recorded on phones, fitness watches, and GPS devices.

Techniques:

Comparison of tools to monitor recreation use. The table includes a description of how each tool quantifies recreation use, data type (resolution), minimum temporal grain, temporal and spatial extent, recreation activity type (motorized, non-motorized, all recreation activity types), season (summer, winter, year round).

Journal: PeerJ

Article Title: Advancements in monitoring: a comparison of traditional and application-based tools for measuring outdoor recreation

doi: 10.7717/peerj.17744

Figure Lengend Snippet: Comparison of tools to monitor recreation use. The table includes a description of how each tool quantifies recreation use, data type (resolution), minimum temporal grain, temporal and spatial extent, recreation activity type (motorized, non-motorized, all recreation activity types), season (summer, winter, year round).

Article Snippet: Strava Global Heatmap – Strava Global Heatmap (hereafter, Strava Heatmap; https://www.strava.com/heatmap) is a crowdsourced heatmap that uses GPS-based recreation tracks of public non-motorized recreation activities (run, hike, walk, ride, water, winter) recorded on phones, fitness watches, and GPS devices.

Techniques: Comparison, Activity Assay

Data for cameras, counters and Strava Metro are from 2017 to 2019 for all spatially matched locations in the study area, data from Strava Heatmap is from 2016 to 2017. Trendline represented in red.

Journal: PeerJ

Article Title: Advancements in monitoring: a comparison of traditional and application-based tools for measuring outdoor recreation

doi: 10.7717/peerj.17744

Figure Lengend Snippet: Data for cameras, counters and Strava Metro are from 2017 to 2019 for all spatially matched locations in the study area, data from Strava Heatmap is from 2016 to 2017. Trendline represented in red.

Article Snippet: Strava Global Heatmap – Strava Global Heatmap (hereafter, Strava Heatmap; https://www.strava.com/heatmap) is a crowdsourced heatmap that uses GPS-based recreation tracks of public non-motorized recreation activities (run, hike, walk, ride, water, winter) recorded on phones, fitness watches, and GPS devices.

Techniques: