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Image Search Results
Journal: Developmental cell
Article Title: Tumor Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
doi: 10.1016/j.devcel.2017.10.027
Figure Lengend Snippet: (A) Heterogeneous abundance of GDF11 mRNA (red) measured by RNA FISH with a nuclear counterstain (blue).
Article Snippet: Addgene #47553 pBabe RasV12 puro Bob Weinberg Addgene #1768 pLenti PGK V5-luciferase (w528-1) blast Campeau et al., 2009 Addgene #19166 pDONR223 LacZ Yang et al., 2011 Addgene #25893 pDONR223 Luciferase Yang et al., 2011
Techniques:
Journal: Developmental cell
Article Title: Tumor Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
doi: 10.1016/j.devcel.2017.10.027
Figure Lengend Snippet: (A) SMAD4 knockdown blocks the ability of GDF11 to inhibit 3D invasion in MDA-MB-231 cells. shLuc was induced as a control shRNA.
Article Snippet: Addgene #47553 pBabe RasV12 puro Bob Weinberg Addgene #1768 pLenti PGK V5-luciferase (w528-1) blast Campeau et al., 2009 Addgene #19166 pDONR223 LacZ Yang et al., 2011 Addgene #25893 pDONR223 Luciferase Yang et al., 2011
Techniques: Knockdown, Control, shRNA
Journal: Developmental cell
Article Title: Tumor Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
doi: 10.1016/j.devcel.2017.10.027
Figure Lengend Snippet: (A) Genetic alterations in GDF11 are frequent in salivary adenoid cystic carcinoma (ACC) but rare in breast cancer.
Article Snippet: Addgene #47553 pBabe RasV12 puro Bob Weinberg Addgene #1768 pLenti PGK V5-luciferase (w528-1) blast Campeau et al., 2009 Addgene #19166 pDONR223 LacZ Yang et al., 2011 Addgene #25893 pDONR223 Luciferase Yang et al., 2011
Techniques:
Journal: Developmental cell
Article Title: Tumor Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
doi: 10.1016/j.devcel.2017.10.027
Figure Lengend Snippet: (A and B) Recombinant GDF11 promotes rounding of invasive MCF10A-5E cells transformed with H-RasV12 (5E RasV12) (A) and inhibits invasion of MDA-MB-231 claudin-low TNBC cells (B).
Article Snippet: Addgene #47553 pBabe RasV12 puro Bob Weinberg Addgene #1768 pLenti PGK V5-luciferase (w528-1) blast Campeau et al., 2009 Addgene #19166 pDONR223 LacZ Yang et al., 2011 Addgene #25893 pDONR223 Luciferase Yang et al., 2011
Techniques: Recombinant, Transformation Assay
Journal: Developmental cell
Article Title: Tumor Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
doi: 10.1016/j.devcel.2017.10.027
Figure Lengend Snippet: (A) Tumor bioluminescence of MCF10DCIS.com (Miller et al., 2000) intraductal xenografts upon inducible knockdown of GDF11 at day 14.
Article Snippet: Addgene #47553 pBabe RasV12 puro Bob Weinberg Addgene #1768 pLenti PGK V5-luciferase (w528-1) blast Campeau et al., 2009 Addgene #19166 pDONR223 LacZ Yang et al., 2011 Addgene #25893 pDONR223 Luciferase Yang et al., 2011
Techniques: Knockdown
Journal: Developmental cell
Article Title: Tumor Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
doi: 10.1016/j.devcel.2017.10.027
Figure Lengend Snippet: (A–D) Elevated abundance of total GDF11 protein in ductal carcinoma in situ (DCIS) lesions and TNBC specimens as assessed by the EPR monoclonal antibody. Total GDF11–EPR immunoreactivity was scored in (D).
Article Snippet: Addgene #47553 pBabe RasV12 puro Bob Weinberg Addgene #1768 pLenti PGK V5-luciferase (w528-1) blast Campeau et al., 2009 Addgene #19166 pDONR223 LacZ Yang et al., 2011 Addgene #25893 pDONR223 Luciferase Yang et al., 2011
Techniques: In Situ
Journal: Developmental cell
Article Title: Tumor Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
doi: 10.1016/j.devcel.2017.10.027
Figure Lengend Snippet: KEY RESOURCES TABLE
Article Snippet: Addgene #47553 pBabe RasV12 puro Bob Weinberg Addgene #1768 pLenti PGK V5-luciferase (w528-1) blast Campeau et al., 2009 Addgene #19166 pDONR223 LacZ Yang et al., 2011 Addgene #25893 pDONR223 Luciferase Yang et al., 2011
Techniques: Virus, In Situ, Recombinant, Enzyme-linked Immunosorbent Assay, Mutagenesis, RNA Amplification, Expressing, Real-time Polymerase Chain Reaction, Luciferase, Software