cyclothiazide Search Results


93
Alomone Labs cdtx
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95
Tocris cyclothiazide
EC 50 , EC 2X and maximal potentiation values obtained with S 47445 and other positive allosteric modulators at rat or human AMPA receptors on oocytes injected with poly(A+) mRNA.
Cyclothiazide, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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91
Santa Cruz Biotechnology cyclothiazide
A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM <t>cyclothiazide.</t> Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).
Cyclothiazide, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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93
Selleck Chemicals cycloheximide
A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM <t>cyclothiazide.</t> Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).
Cycloheximide, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Enzo Biochem cyclothiazide
A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM <t>cyclothiazide.</t> Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).
Cyclothiazide, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Molegro ApS cyclothiazide
A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM <t>cyclothiazide.</t> Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).
Cyclothiazide, supplied by Molegro ApS, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Microm International GmbH cyclothiazide
A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM <t>cyclothiazide.</t> Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).
Cyclothiazide, supplied by Microm International GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Biomol GmbH cyclothiazide
A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM <t>cyclothiazide.</t> Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).
Cyclothiazide, supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Enzo Biochem 100 μm cyclothiazide (ctz)
A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM <t>cyclothiazide.</t> Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).
100 μm Cyclothiazide (Ctz), supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
SATAKE cyclothiazide
A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM <t>cyclothiazide.</t> Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).
Cyclothiazide, supplied by SATAKE, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
LC Laboratories cyclothiazide
A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM <t>cyclothiazide.</t> Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).
Cyclothiazide, supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


EC 50 , EC 2X and maximal potentiation values obtained with S 47445 and other positive allosteric modulators at rat or human AMPA receptors on oocytes injected with poly(A+) mRNA.

Journal: PLoS ONE

Article Title: Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptors

doi: 10.1371/journal.pone.0184429

Figure Lengend Snippet: EC 50 , EC 2X and maximal potentiation values obtained with S 47445 and other positive allosteric modulators at rat or human AMPA receptors on oocytes injected with poly(A+) mRNA.

Article Snippet: Cyclothiazide was obtained from Tocris Bioscience, Lille, France.

Techniques: Injection

A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM cyclothiazide. Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).

Journal: PLoS ONE

Article Title: Temperature effects on synaptic transmission and neuronal function in the visual thalamus

doi: 10.1371/journal.pone.0232451

Figure Lengend Snippet: A) Overlaid voltage-clamp recordings from a TC neuron from a Chx10-Cre;Ai32 mouse in response to pairs of 460 nm LED stimuli with intervals of 100, 200, 500, and 1000 ms (blue) at 23°C and 31°C in the presence of 200 μM γDGG and 100 μM cyclothiazide. Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). B) Plot of paired pulse ratio (PPR = EPSC2/EPSC1) showing that synaptic depression was increased following warming of the bath solution (n = 6). **p<0.01; ***p<0.001, t-test. C) Measurements of EPSC amplitude at room temperature and in warmed conditions (n = 8).

Article Snippet: For measurements of short-term synaptic plasticity and retinogeniculate synaptic vesicle release probability, the bath was supplemented with 200 μM γD-glutamylglycine (γDGG, Abcam, Cambridge, MA) and 100 μM cyclothiazide (Santa Cruz, Dallas, TX) [ ].

Techniques:

A) Voltage-clamp recordings from a dLGN TC neuron EPSCs in response to a 10 Hz stimulation of retinal ganglion cell axons using a 460 nm LED in a brain slice from a Chx10-Cre;Ai32 mouse. Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). Each trace is the average of 3–5 individual responses to the same stimulus. B) Plot of cumulative EPSC amplitude and linear fit to the responses at pulses 15–30. Extrapolation to the Y-intercept is used as a measure of vesicle pool size while the slope is a measure of replenishment rate. Release probability is calculated as the ratio of the first EPSC to the Y-intercept. C) Vesicle release probability increased with warming the bath solution (n = 7 TC neuron recordings). D) Vesicle pool replenishment rate (slope of the fit in panel B) also increased with warming. E) The Y-intercept, which is a measure of vesicle pool size was not changed by warming.

Journal: PLoS ONE

Article Title: Temperature effects on synaptic transmission and neuronal function in the visual thalamus

doi: 10.1371/journal.pone.0232451

Figure Lengend Snippet: A) Voltage-clamp recordings from a dLGN TC neuron EPSCs in response to a 10 Hz stimulation of retinal ganglion cell axons using a 460 nm LED in a brain slice from a Chx10-Cre;Ai32 mouse. Recordings were made in the presence of γDGG (200 μM) and cyclothiazide (100 μM). Each trace is the average of 3–5 individual responses to the same stimulus. B) Plot of cumulative EPSC amplitude and linear fit to the responses at pulses 15–30. Extrapolation to the Y-intercept is used as a measure of vesicle pool size while the slope is a measure of replenishment rate. Release probability is calculated as the ratio of the first EPSC to the Y-intercept. C) Vesicle release probability increased with warming the bath solution (n = 7 TC neuron recordings). D) Vesicle pool replenishment rate (slope of the fit in panel B) also increased with warming. E) The Y-intercept, which is a measure of vesicle pool size was not changed by warming.

Article Snippet: For measurements of short-term synaptic plasticity and retinogeniculate synaptic vesicle release probability, the bath was supplemented with 200 μM γD-glutamylglycine (γDGG, Abcam, Cambridge, MA) and 100 μM cyclothiazide (Santa Cruz, Dallas, TX) [ ].

Techniques: Slice Preparation