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Image Search Results
Journal: International immunopharmacology
Article Title: Immunomodulatory effects of recombinant lactoferrin during MRSA infection
doi: 10.1016/j.intimp.2014.02.029
Figure Lengend Snippet: BALB/c mice were infected IP with MRSA (LD100) were treated at 2 hours post-infection with rmLF (100µg/mouse). Survival was monitored post-infection. Control (non-treated) mice succumbed to MRSA infection within 24 hours. Mice treated with rmLF demonstrated increased survival. Data representative of two experimental repeats with 8 mice per experiment.
Article Snippet: Methicillin-resistant
Techniques: Infection, Control
Journal: International immunopharmacology
Article Title: Immunomodulatory effects of recombinant lactoferrin during MRSA infection
doi: 10.1016/j.intimp.2014.02.029
Figure Lengend Snippet: BALB/c mice were infected with MRSA (LD100) and treated with 100µg/mouse rmLF at 2 hours post-infection. Blood was collected 1 hour later and colony forming units (CFU) were enumerated. Mice treated with rmLF showed a slight, but non-significant, decrease compared to non-treated controls. Data graphed as mean +/− standard deviation, log scale. Data representative of three experimental repeats with 4–5 mice per experiment.
Article Snippet: Methicillin-resistant
Techniques: Infection, Standard Deviation
Journal: International immunopharmacology
Article Title: Immunomodulatory effects of recombinant lactoferrin during MRSA infection
doi: 10.1016/j.intimp.2014.02.029
Figure Lengend Snippet: MRSA-infected mice given rmLF as described in Figures 1 and and22 demonstrated significant decrease in IL-17, but not IL-6. Data representative of three experimental repeats with at least 5 mice per experiment; rmLF alone did not induce responses above background levels. N=8 depicted with mean +/− standard deviation.
Article Snippet: Methicillin-resistant
Techniques: Infection, Standard Deviation
Journal: International immunopharmacology
Article Title: Immunomodulatory effects of recombinant lactoferrin during MRSA infection
doi: 10.1016/j.intimp.2014.02.029
Figure Lengend Snippet: Modulation of pro-inflammatory cytokine production from MRSA-infected mouse splenocytes treated with rmLF.
Article Snippet: Methicillin-resistant
Techniques:
Journal: International immunopharmacology
Article Title: Immunomodulatory effects of recombinant lactoferrin during MRSA infection
doi: 10.1016/j.intimp.2014.02.029
Figure Lengend Snippet: TNF-α production from MRSA infected granulocytes after rmouseLF treatment.
Article Snippet: Methicillin-resistant
Techniques: Infection
Journal: International immunopharmacology
Article Title: Immunomodulatory effects of recombinant lactoferrin during MRSA infection
doi: 10.1016/j.intimp.2014.02.029
Figure Lengend Snippet: Human blood monocytes isolated from healthy human buffy coats were infected with MRSA (MOI 1:10) and treated with rhLF at 2 hours post-infected were analyzed for cytokine production at 6 hours post-treatment. Addition of rhLF at 100µg/mL increased MRSA-infected PBMC production of IFN-γ and IL-2. rhLF alone did not induce responses above background levels. Data represented as box and whiskers with the box expressing mean, minimum, and maximum, and whiskers as standard deviation. ***=p<0.001
Article Snippet: Methicillin-resistant
Techniques: Isolation, Infection, Expressing, Standard Deviation
Journal: International immunopharmacology
Article Title: Immunomodulatory effects of recombinant lactoferrin during MRSA infection
doi: 10.1016/j.intimp.2014.02.029
Figure Lengend Snippet: Human blood monocytes isolated from healthy human buffy coats were infected with MRSA (MOI 1:10) and treated with rhLF at 2 hours postinfected were analyzed for cytokine production at 6 hours post-treatment. Treatment with rhumanLF decreased levels of IL-6, IL-1β, and IL-12p40. A non-significant decrease was also observed in IL-10. *=p<0.05; **=p<0.01; ***=p<0.001
Article Snippet: Methicillin-resistant
Techniques: Isolation, Infection
Journal: International immunopharmacology
Article Title: Immunomodulatory effects of recombinant lactoferrin during MRSA infection
doi: 10.1016/j.intimp.2014.02.029
Figure Lengend Snippet: Granulocytes isolated from human buffy coats were infected with MRSA (MOI 1:10) and treated with rhLF at 2 hours post-infection. Supernatants were collected and analyzed by ELISA at 6 hours post-treatment. While there was no change in TNF-α, addition of rhLF led to an increase in IL-1β production from MRSA-infected granulocytes. Data represented as box and whiskers with the box expressing mean, minimum, and maximum, and whiskers as standard deviation. *=p<0.05
Article Snippet: Methicillin-resistant
Techniques: Isolation, Infection, Enzyme-linked Immunosorbent Assay, Expressing, Standard Deviation