cl075 Search Results


cl075  (Tocris)
93
Tocris cl075
Cl075, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cl075/pm40615103-110-36-56?v=Tocris
Average 93 stars, based on 1 article reviews
cl075 - by Bioz Stars, 2026-08
93/100 stars
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polymersome nanocarrier encapsulating cl075  (NanoCarrier Co)
90
NanoCarrier Co polymersome nanocarrier encapsulating cl075
Polymersome Nanocarrier Encapsulating Cl075, supplied by NanoCarrier Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cl075/10__1016_slash_j__ejmech__2020__112238-470-1-2?v=NanoCarrier+Co
Average 90 stars, based on 1 article reviews
polymersome nanocarrier encapsulating cl075 - by Bioz Stars, 2026-08
90/100 stars
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cl075:ag85bp25-ps containing approximately 8 to 10 μg of ag85b/p25  (Biomatik)
90
Biomatik cl075:ag85bp25-ps containing approximately 8 to 10 μg of ag85b/p25
CL075:Ag85Bp25-PS and BCG induce comparable <t>Ag85B-specific</t> CD4 + effector T cells in the spleens of neonatal huTLR8Tg mice. A, Experimental design: 7-day-old huTLR8Tg and matched littermate WT mice were immunized subcutaneously and killed 14 days later before harvesting spleens and staining splenocytes with a control versus Ag85B 280–294 MHCII tetramer and for surface marker expression. B, Representative flow cytometric plots showing Tet + T cells as CD44 + Neg Tet + or CD44 + Ag85B Tet + cells gated on live CD4 + splenic lymphocytes of BCG- or CL075-Ag85Bp25-PS–vaccinated mice 2 weeks after immunization. C and D, Similar to BCG, CL075-Ag85Bp25-PS induced a significant increase in CD44 + Ag85B Tet + cells compared with CD44 + Neg Tet + cells. Results represent means ± SEMs (n = 14-15), with significance relative to unspecific control tetramer. E, Neonatal humanized TLR8 mice have greater numbers of splenic Ag85B-specific CD4 + T cells versus their WT littermates. The unpaired Mann-Whitney test was applied, and statistical significance was denoted as follows: ** P < .01 and *** P < .001. NS , Not significant.
Cl075:Ag85bp25 Ps Containing Approximately 8 To 10 μg Of Ag85b/P25, supplied by Biomatik, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cl075/pmc05667586-43-33-34?v=Biomatik
Average 90 stars, based on 1 article reviews
cl075:ag85bp25-ps containing approximately 8 to 10 μg of ag85b/p25 - by Bioz Stars, 2026-08
90/100 stars
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synthetic thiazoloquinoline immunostimulatory compound cl075  (Helmholtz Zentrum fur Infektionsforschung GmbH)
90
Helmholtz Zentrum fur Infektionsforschung GmbH synthetic thiazoloquinoline immunostimulatory compound cl075
CL075:Ag85Bp25-PS and BCG induce comparable <t>Ag85B-specific</t> CD4 + effector T cells in the spleens of neonatal huTLR8Tg mice. A, Experimental design: 7-day-old huTLR8Tg and matched littermate WT mice were immunized subcutaneously and killed 14 days later before harvesting spleens and staining splenocytes with a control versus Ag85B 280–294 MHCII tetramer and for surface marker expression. B, Representative flow cytometric plots showing Tet + T cells as CD44 + Neg Tet + or CD44 + Ag85B Tet + cells gated on live CD4 + splenic lymphocytes of BCG- or CL075-Ag85Bp25-PS–vaccinated mice 2 weeks after immunization. C and D, Similar to BCG, CL075-Ag85Bp25-PS induced a significant increase in CD44 + Ag85B Tet + cells compared with CD44 + Neg Tet + cells. Results represent means ± SEMs (n = 14-15), with significance relative to unspecific control tetramer. E, Neonatal humanized TLR8 mice have greater numbers of splenic Ag85B-specific CD4 + T cells versus their WT littermates. The unpaired Mann-Whitney test was applied, and statistical significance was denoted as follows: ** P < .01 and *** P < .001. NS , Not significant.
Synthetic Thiazoloquinoline Immunostimulatory Compound Cl075, supplied by Helmholtz Zentrum fur Infektionsforschung GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cl075/pm20511554-32-12-79?v=Helmholtz+Zentrum+fur+Infektionsforschung+GmbH
Average 90 stars, based on 1 article reviews
synthetic thiazoloquinoline immunostimulatory compound cl075 - by Bioz Stars, 2026-08
90/100 stars
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cl075 (tlr8)  (Vivogen Biotechnology Inc)
90
Vivogen Biotechnology Inc cl075 (tlr8)
CL075:Ag85Bp25-PS and BCG induce comparable <t>Ag85B-specific</t> CD4 + effector T cells in the spleens of neonatal huTLR8Tg mice. A, Experimental design: 7-day-old huTLR8Tg and matched littermate WT mice were immunized subcutaneously and killed 14 days later before harvesting spleens and staining splenocytes with a control versus Ag85B 280–294 MHCII tetramer and for surface marker expression. B, Representative flow cytometric plots showing Tet + T cells as CD44 + Neg Tet + or CD44 + Ag85B Tet + cells gated on live CD4 + splenic lymphocytes of BCG- or CL075-Ag85Bp25-PS–vaccinated mice 2 weeks after immunization. C and D, Similar to BCG, CL075-Ag85Bp25-PS induced a significant increase in CD44 + Ag85B Tet + cells compared with CD44 + Neg Tet + cells. Results represent means ± SEMs (n = 14-15), with significance relative to unspecific control tetramer. E, Neonatal humanized TLR8 mice have greater numbers of splenic Ag85B-specific CD4 + T cells versus their WT littermates. The unpaired Mann-Whitney test was applied, and statistical significance was denoted as follows: ** P < .01 and *** P < .001. NS , Not significant.
Cl075 (Tlr8), supplied by Vivogen Biotechnology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cl075/pm36203578-48-14-18?v=Vivogen+Biotechnology+Inc
Average 90 stars, based on 1 article reviews
cl075 (tlr8) - by Bioz Stars, 2026-08
90/100 stars
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cl075 (3 mg/ml)  (SAS institute)
90
SAS institute cl075 (3 mg/ml)
CL075:Ag85Bp25-PS and BCG induce comparable <t>Ag85B-specific</t> CD4 + effector T cells in the spleens of neonatal huTLR8Tg mice. A, Experimental design: 7-day-old huTLR8Tg and matched littermate WT mice were immunized subcutaneously and killed 14 days later before harvesting spleens and staining splenocytes with a control versus Ag85B 280–294 MHCII tetramer and for surface marker expression. B, Representative flow cytometric plots showing Tet + T cells as CD44 + Neg Tet + or CD44 + Ag85B Tet + cells gated on live CD4 + splenic lymphocytes of BCG- or CL075-Ag85Bp25-PS–vaccinated mice 2 weeks after immunization. C and D, Similar to BCG, CL075-Ag85Bp25-PS induced a significant increase in CD44 + Ag85B Tet + cells compared with CD44 + Neg Tet + cells. Results represent means ± SEMs (n = 14-15), with significance relative to unspecific control tetramer. E, Neonatal humanized TLR8 mice have greater numbers of splenic Ag85B-specific CD4 + T cells versus their WT littermates. The unpaired Mann-Whitney test was applied, and statistical significance was denoted as follows: ** P < .01 and *** P < .001. NS , Not significant.
Cl075 (3 Mg/Ml), supplied by SAS institute, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cl075/10__1158_slash_0008___5472__can___12___3058-49-12-20?v=SAS+institute
Average 90 stars, based on 1 article reviews
cl075 (3 mg/ml) - by Bioz Stars, 2026-08
90/100 stars
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cl 075  (Bio-Techne corporation)
90
Bio-Techne corporation cl 075
CL075:Ag85Bp25-PS and BCG induce comparable <t>Ag85B-specific</t> CD4 + effector T cells in the spleens of neonatal huTLR8Tg mice. A, Experimental design: 7-day-old huTLR8Tg and matched littermate WT mice were immunized subcutaneously and killed 14 days later before harvesting spleens and staining splenocytes with a control versus Ag85B 280–294 MHCII tetramer and for surface marker expression. B, Representative flow cytometric plots showing Tet + T cells as CD44 + Neg Tet + or CD44 + Ag85B Tet + cells gated on live CD4 + splenic lymphocytes of BCG- or CL075-Ag85Bp25-PS–vaccinated mice 2 weeks after immunization. C and D, Similar to BCG, CL075-Ag85Bp25-PS induced a significant increase in CD44 + Ag85B Tet + cells compared with CD44 + Neg Tet + cells. Results represent means ± SEMs (n = 14-15), with significance relative to unspecific control tetramer. E, Neonatal humanized TLR8 mice have greater numbers of splenic Ag85B-specific CD4 + T cells versus their WT littermates. The unpaired Mann-Whitney test was applied, and statistical significance was denoted as follows: ** P < .01 and *** P < .001. NS , Not significant.
Cl 075, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cl075/custom%406142%4030930145?v=Bio-Techne+corporation
Average 90 stars, based on 1 article reviews
cl 075 - by Bioz Stars, 2026-08
90/100 stars
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cl075  (MedChemExpress)
N/A
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cl 075  (Aladdin Scientific Corporation)
N/A
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cl075  (TargetMol)
N/A
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cl075  (BOC Sciences)
N/A
A thiazoloquinolone derivative that stimulates TLR8 in human peripheral blood mononuclear cells
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cl075  (InvivoGen)
N/A
Thiazoloquinoline compound
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Image Search Results


CL075:Ag85Bp25-PS and BCG induce comparable Ag85B-specific CD4 + effector T cells in the spleens of neonatal huTLR8Tg mice. A, Experimental design: 7-day-old huTLR8Tg and matched littermate WT mice were immunized subcutaneously and killed 14 days later before harvesting spleens and staining splenocytes with a control versus Ag85B 280–294 MHCII tetramer and for surface marker expression. B, Representative flow cytometric plots showing Tet + T cells as CD44 + Neg Tet + or CD44 + Ag85B Tet + cells gated on live CD4 + splenic lymphocytes of BCG- or CL075-Ag85Bp25-PS–vaccinated mice 2 weeks after immunization. C and D, Similar to BCG, CL075-Ag85Bp25-PS induced a significant increase in CD44 + Ag85B Tet + cells compared with CD44 + Neg Tet + cells. Results represent means ± SEMs (n = 14-15), with significance relative to unspecific control tetramer. E, Neonatal humanized TLR8 mice have greater numbers of splenic Ag85B-specific CD4 + T cells versus their WT littermates. The unpaired Mann-Whitney test was applied, and statistical significance was denoted as follows: ** P < .01 and *** P < .001. NS , Not significant.

Journal: The Journal of Allergy and Clinical Immunology

Article Title: Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses

doi: 10.1016/j.jaci.2016.12.985

Figure Lengend Snippet: CL075:Ag85Bp25-PS and BCG induce comparable Ag85B-specific CD4 + effector T cells in the spleens of neonatal huTLR8Tg mice. A, Experimental design: 7-day-old huTLR8Tg and matched littermate WT mice were immunized subcutaneously and killed 14 days later before harvesting spleens and staining splenocytes with a control versus Ag85B 280–294 MHCII tetramer and for surface marker expression. B, Representative flow cytometric plots showing Tet + T cells as CD44 + Neg Tet + or CD44 + Ag85B Tet + cells gated on live CD4 + splenic lymphocytes of BCG- or CL075-Ag85Bp25-PS–vaccinated mice 2 weeks after immunization. C and D, Similar to BCG, CL075-Ag85Bp25-PS induced a significant increase in CD44 + Ag85B Tet + cells compared with CD44 + Neg Tet + cells. Results represent means ± SEMs (n = 14-15), with significance relative to unspecific control tetramer. E, Neonatal humanized TLR8 mice have greater numbers of splenic Ag85B-specific CD4 + T cells versus their WT littermates. The unpaired Mann-Whitney test was applied, and statistical significance was denoted as follows: ** P < .01 and *** P < .001. NS , Not significant.

Article Snippet: Mice were immunized subcutaneously at the scruff of the neck with either 0.2 × 10 6 colony-forming units of BCG (Organon Teknika/Merck, Durham, NC) or CL075:Ag85Bp25-PS containing approximately 8 to 10 μg of Ag85B/p25 (Biomatik, Cambridge, Ontario, Canada) and approximately 0.1 mg/kg CL075 in a total volume of 25 μL.

Techniques: Staining, Marker, Expressing, MANN-WHITNEY