ck636 Search Results


ck-636  (MuseChem Chemicals)
N/A
CK-636 (CAT: I003566), also known as CK-0944636, is a small molecule inhibitor of the Arp2/3 complex. It functions by inhibiting actin polymerization, which is a critical process for cell motility and cytoskeletal dynamics. By targeting
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ck-636  (1PlusChem LLC)
N/A
CK-636
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ck636  (Selleck Chemicals)
92
Selleck Chemicals ck636
(A) Cells were treated by ArpC specific inhibitor <t>CK636</t> for 24 hours. Cell viability was determined by Trypan Blue assay. (B) CD133+ cells were cultured in 10% serum-containing medium to induce lamellipodia. The suppression of lamellipodia formation was observed through confocal microscope after CK636 (2μM) treatment for 30 minutes (Orange: actin filaments, Blue: Nucleus). (C) HES1 expression was determined after CK636 treatment for 24 hours with different doses. (D) HES1 expression was measured after CK-636 (2μM) treatment for different periods. (E) Protein expression was detected by Western blot after shArp2 and CK636 (2μM) treatment for 24 hours.
Ck636, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ck636/CK-636/pmc05464873-179-6-7
Average 92 stars, based on 1 article reviews
ck636 - by Bioz Stars, 2026-09
92/100 stars
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ck 636  (MedChemExpress)
93
MedChemExpress ck 636
(A) Cells were treated by ArpC specific inhibitor <t>CK636</t> for 24 hours. Cell viability was determined by Trypan Blue assay. (B) CD133+ cells were cultured in 10% serum-containing medium to induce lamellipodia. The suppression of lamellipodia formation was observed through confocal microscope after CK636 (2μM) treatment for 30 minutes (Orange: actin filaments, Blue: Nucleus). (C) HES1 expression was determined after CK636 treatment for 24 hours with different doses. (D) HES1 expression was measured after CK-636 (2μM) treatment for different periods. (E) Protein expression was detected by Western blot after shArp2 and CK636 (2μM) treatment for 24 hours.
Ck 636, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ck636/CK-636/pm35665815-239-24-25
Average 93 stars, based on 1 article reviews
ck 636 - by Bioz Stars, 2026-09
93/100 stars
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ck-636  (ApexBio)
90
ApexBio ck-636
(A) Cells were treated by ArpC specific inhibitor <t>CK636</t> for 24 hours. Cell viability was determined by Trypan Blue assay. (B) CD133+ cells were cultured in 10% serum-containing medium to induce lamellipodia. The suppression of lamellipodia formation was observed through confocal microscope after CK636 (2μM) treatment for 30 minutes (Orange: actin filaments, Blue: Nucleus). (C) HES1 expression was determined after CK636 treatment for 24 hours with different doses. (D) HES1 expression was measured after CK-636 (2μM) treatment for different periods. (E) Protein expression was detected by Western blot after shArp2 and CK636 (2μM) treatment for 24 hours.
Ck 636, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ck636/ck+636/pmc04749184-236-20-25
Average 90 stars, based on 1 article reviews
ck-636 - by Bioz Stars, 2026-09
90/100 stars
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ck-636  (Enamine Ltd)
90
Enamine Ltd ck-636
(A) Cells were treated by ArpC specific inhibitor <t>CK636</t> for 24 hours. Cell viability was determined by Trypan Blue assay. (B) CD133+ cells were cultured in 10% serum-containing medium to induce lamellipodia. The suppression of lamellipodia formation was observed through confocal microscope after CK636 (2μM) treatment for 30 minutes (Orange: actin filaments, Blue: Nucleus). (C) HES1 expression was determined after CK636 treatment for 24 hours with different doses. (D) HES1 expression was measured after CK-636 (2μM) treatment for different periods. (E) Protein expression was detected by Western blot after shArp2 and CK636 (2μM) treatment for 24 hours.
Ck 636, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ck636/CK-636/custom%40en300-7386601%40pmc07672456__gkaa862_supplemental_file
Average 90 stars, based on 1 article reviews
ck-636 - by Bioz Stars, 2026-09
90/100 stars
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ck-636  (Aladdin Scientific Corporation)
N/A
CK-636 is an Arp2/3 complex inhibitor with IC50 of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively
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ck 636  (Cayman Chemical)
N/A
Actin related protein 3 Arp3 heterodimerizes with Arp2 to form the Arp2 3 complex which is involved in actin polymerization in a range of cell types CK 636 is an inhibitor of Arp2 3 complex
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ck-636  (BOC Sciences)
N/A
CK-636 is an Arp2/3 complex inhibitor. CK-636 binds between Arp2 and Arp3, where it appears to block movement of Arp2 and Arp3 into their active conformation. CK-636 inserts into the hydrophobic core of Arp3 and
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ck-636  (TargetMol)
N/A
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ck-636  (Biosynth Carbosynth)
N/A
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Image Search Results


(A) Cells were treated by ArpC specific inhibitor CK636 for 24 hours. Cell viability was determined by Trypan Blue assay. (B) CD133+ cells were cultured in 10% serum-containing medium to induce lamellipodia. The suppression of lamellipodia formation was observed through confocal microscope after CK636 (2μM) treatment for 30 minutes (Orange: actin filaments, Blue: Nucleus). (C) HES1 expression was determined after CK636 treatment for 24 hours with different doses. (D) HES1 expression was measured after CK-636 (2μM) treatment for different periods. (E) Protein expression was detected by Western blot after shArp2 and CK636 (2μM) treatment for 24 hours.

Journal: Oncotarget

Article Title: Actin cytoskeleton regulator Arp2/3 complex is required for DLL1 activating Notch1 signaling to maintain the stem cell phenotype of glioma initiating cells

doi: 10.18632/oncotarget.16495

Figure Lengend Snippet: (A) Cells were treated by ArpC specific inhibitor CK636 for 24 hours. Cell viability was determined by Trypan Blue assay. (B) CD133+ cells were cultured in 10% serum-containing medium to induce lamellipodia. The suppression of lamellipodia formation was observed through confocal microscope after CK636 (2μM) treatment for 30 minutes (Orange: actin filaments, Blue: Nucleus). (C) HES1 expression was determined after CK636 treatment for 24 hours with different doses. (D) HES1 expression was measured after CK-636 (2μM) treatment for different periods. (E) Protein expression was detected by Western blot after shArp2 and CK636 (2μM) treatment for 24 hours.

Article Snippet: Cells were fixed after 30 minutes CK636 (Selleckchem #S7497, US) treatment for cytoskeleton structure assessment, and total protein was extracted after 24 hours treatment for expression detection.

Techniques: Cell Culture, Microscopy, Expressing, Western Blot

(A) Membrane and cytoplasmic proteins were extracted separately. Sodium potassium ATPase and a-tubulin served as membrane (Mem) and cytoplasmic (Cyto) loading control, respectively. DLL1 expression was detected. (B) DLL1 expression of shArp2 and CK636-treated cells was immunofluorescence stained for confocal microscope observation. Green: DLL1. Blue: Nucleus.

Journal: Oncotarget

Article Title: Actin cytoskeleton regulator Arp2/3 complex is required for DLL1 activating Notch1 signaling to maintain the stem cell phenotype of glioma initiating cells

doi: 10.18632/oncotarget.16495

Figure Lengend Snippet: (A) Membrane and cytoplasmic proteins were extracted separately. Sodium potassium ATPase and a-tubulin served as membrane (Mem) and cytoplasmic (Cyto) loading control, respectively. DLL1 expression was detected. (B) DLL1 expression of shArp2 and CK636-treated cells was immunofluorescence stained for confocal microscope observation. Green: DLL1. Blue: Nucleus.

Article Snippet: Cells were fixed after 30 minutes CK636 (Selleckchem #S7497, US) treatment for cytoskeleton structure assessment, and total protein was extracted after 24 hours treatment for expression detection.

Techniques: Membrane, Control, Expressing, Immunofluorescence, Staining, Microscopy