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Image Search Results
Journal: Journal of Clinical Laboratory Analysis
Article Title: Circulating cell‐free circRNA panel predicted tumorigenesis and development of colorectal cancer
doi: 10.1002/jcla.24431
Figure Lengend Snippet: Circulating circRNAs expression landscape of in CRC, CRA, and healthy control samples. (A and B) Cluster analysis of differentially expressed circRNA in each group. (C) Volcano blot presented differentially expressed circRNA. (D) Intersection matching analysis of CRA group and healthy control compared with CRC group. CRA, colorectal adenomas; CRC, colorectal cancer
Article Snippet: The
Techniques: Expressing, Control
Journal: Journal of Clinical Laboratory Analysis
Article Title: Circulating cell‐free circRNA panel predicted tumorigenesis and development of colorectal cancer
doi: 10.1002/jcla.24431
Figure Lengend Snippet: Relative expression of circRNA in training set. The eight circRNAs were examined in 20 paired samples of three group. Data was presented as mean ± SD, **indicated p < 0.01. *indicated p < 0.05, n.s, indicated no significance
Article Snippet: The
Techniques: Expressing
Journal: Journal of Clinical Laboratory Analysis
Article Title: Circulating cell‐free circRNA panel predicted tumorigenesis and development of colorectal cancer
doi: 10.1002/jcla.24431
Figure Lengend Snippet: Relative expression of candidate circRNA in independent cohort. The eight circRNAs were examined in 80 paired plasma samples from healthy controls, CRA patients and CRC patients. **indicated p < 0.01. *indicated p < 0.05, n.s, indicated no significance
Article Snippet: The
Techniques: Expressing, Clinical Proteomics
Journal: Journal of Clinical Laboratory Analysis
Article Title: Circulating cell‐free circRNA panel predicted tumorigenesis and development of colorectal cancer
doi: 10.1002/jcla.24431
Figure Lengend Snippet: CircRNA panel predicted CRC from healthy controls. (A) Diagnostic efficacy of three circRNA panel as diagnostic marker for colorectal cancer in healthy population in training sets. (B) Diagnostic efficacy of three circRNA panel as biomarker of colorectal cancer in healthy population in validation set
Article Snippet: The
Techniques: Diagnostic Assay, Marker, Biomarker Discovery
Journal: Journal of Clinical Laboratory Analysis
Article Title: Circulating cell‐free circRNA panel predicted tumorigenesis and development of colorectal cancer
doi: 10.1002/jcla.24431
Figure Lengend Snippet: CircRNA panel predicted CRC from CRA. (A) Diagnostic efficacy of three circRNA panel as diagnostic marker for colorectal cancer in CRA patients in training sets. (B) Diagnostic efficacy of three circRNA panel as biomarker of colorectal cancer in CRA patients in validation set
Article Snippet: The
Techniques: Diagnostic Assay, Marker, Biomarker Discovery
Journal: Frontiers in Cell and Developmental Biology
Article Title: Differential CircRNA Expression Signatures May Serve as Potential Novel Biomarkers in Prostate Cancer
doi: 10.3389/fcell.2021.605686
Figure Lengend Snippet: Clustering heatmap of microarray data showing differential expression of circRNAs between malignant, benign and normal cell lines. Unsupervised clustering (euclidean distance measure and the “average” agglomeration method) was used for analysis ( n = 3). circRNAs were more likely to be down-regulated in normal and benign cell lines compared to malignant cells.
Article Snippet: The human circular RNA microarray (
Techniques: Microarray, Expressing
Journal: Frontiers in Cell and Developmental Biology
Article Title: Differential CircRNA Expression Signatures May Serve as Potential Novel Biomarkers in Prostate Cancer
doi: 10.3389/fcell.2021.605686
Figure Lengend Snippet: Top 10 down-regulated circRNAs in PCa (malignant vs. normal/benign cell lines)*.
Article Snippet: The human circular RNA microarray (
Techniques:
Journal: Frontiers in Cell and Developmental Biology
Article Title: Differential CircRNA Expression Signatures May Serve as Potential Novel Biomarkers in Prostate Cancer
doi: 10.3389/fcell.2021.605686
Figure Lengend Snippet: Clustering heatmap showing differential expression of circRNAs between AR dependent cells LNCaP, 22Rv1 and VCaP (hormone sensitive) and AR independent cells DU145 and PC-3 (castration resistant). Unsupervised clustering (euclidean distance measure and the “average” agglomeration method) was used for analysis ( n = 3).
Article Snippet: The human circular RNA microarray (
Techniques: Expressing
Journal: Frontiers in Cell and Developmental Biology
Article Title: Differential CircRNA Expression Signatures May Serve as Potential Novel Biomarkers in Prostate Cancer
doi: 10.3389/fcell.2021.605686
Figure Lengend Snippet: Top 10 up-regulated circRNAs in androgen dependent vs. independent cell lines*.
Article Snippet: The human circular RNA microarray (
Techniques:
Journal: Frontiers in Cell and Developmental Biology
Article Title: Differential CircRNA Expression Signatures May Serve as Potential Novel Biomarkers in Prostate Cancer
doi: 10.3389/fcell.2021.605686
Figure Lengend Snippet: Top 10 down-regulated circRNAs in androgen dependent vs. independent cell lines*.
Article Snippet: The human circular RNA microarray (
Techniques:
Journal: Cell Death Discovery
Article Title: CircRNA circ-NNT mediates myocardial ischemia/reperfusion injury through activating pyroptosis by sponging miR-33a-5p and regulating USP46 expression
doi: 10.1038/s41420-021-00706-7
Figure Lengend Snippet: A The heat map shows the 20 differently expressed circRNAs, which were analyzed by circRNAs Arraystar Chip. B The relative mRNA expression of 10 down-regulated circRNAs were detected by qRT-PCR ( n = 10/group). C The relative mRNA expression of 10 up-regulated circRNAs were detected by qRT-PCR ( n = 10/group). D Scheme illustrating the production of circ-NNT. Circ-NNT was formed by back splicing at exon 17 of the NNT gene. E The relative mRNA expression of circ-NNT was shown in a scatter plots (the top upregulated circRNAs), which was measured by qRT-PCR ( n = 10/group). F The gel electrophoresis validated the existence of circ-NNT. G Circ-NNT and NNT mRNA levels in cardiomyocytes with or without RNase R treatment were measured by qRT-PCR. ns: no significant, *** P < 0.0001.
Article Snippet: A The heat map shows the 20 differently expressed circRNAs, which were analyzed by
Techniques: Expressing, Quantitative RT-PCR, Nucleic Acid Electrophoresis