ciclazindol Search Results


ciclazindol  (Pfizer Inc)
90
Pfizer Inc ciclazindol
Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), <t>ciclazindol</t> (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).
Ciclazindol, supplied by Pfizer Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ciclazindol  (Microm International GmbH)
90
Microm International GmbH ciclazindol
Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), <t>ciclazindol</t> (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).
Ciclazindol, supplied by Microm International GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ciclazindol - by Bioz Stars, 2026-02
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ciclazindol  (Rittenhouse Book Distributors)
90
Rittenhouse Book Distributors ciclazindol
Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), <t>ciclazindol</t> (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).
Ciclazindol, supplied by Rittenhouse Book Distributors, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1,3-diazepine derivative ciclazindol  (Wyeth Ayerst Laboratories)
90
Wyeth Ayerst Laboratories 1,3-diazepine derivative ciclazindol
Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), <t>ciclazindol</t> (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).
1,3 Diazepine Derivative Ciclazindol, supplied by Wyeth Ayerst Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/1,3-diazepine derivative ciclazindol/product/Wyeth Ayerst Laboratories
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ciclazindol  (Biolog Inc)
90
Biolog Inc ciclazindol
Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), <t>ciclazindol</t> (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).
Ciclazindol, supplied by Biolog Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ciclazindol (wy23409, figure 33)  (Wyeth Ayerst Laboratories)
90
Wyeth Ayerst Laboratories ciclazindol (wy23409, figure 33)
Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), <t>ciclazindol</t> (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).
Ciclazindol (Wy23409, Figure 33), supplied by Wyeth Ayerst Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ciclazindol (wy23409, figure 33)/product/Wyeth Ayerst Laboratories
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ciclazindol  (Wyeth Ayerst Laboratories)
90
Wyeth Ayerst Laboratories ciclazindol
Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), <t>ciclazindol</t> (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).
Ciclazindol, supplied by Wyeth Ayerst Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), ciclazindol (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).

Journal:

Article Title: Effects of inhibitors of small- and intermediate-conductance calcium-activated potassium channels, inwardly-rectifying potassium channels and Na + /K + ATPase on EDHF relaxations in the rat hepatic artery

doi: 10.1038/sj.bjp.0703226

Figure Lengend Snippet: Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), ciclazindol (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).

Article Snippet: Acetylcholine chloride (Aldrich, Germany); apamin (Alomone Labs, Israel); BaCl 2 , clotrimazole, N ω -nitro- L -arginine hydrochloride, ouabain hydrochloride, L-phenylephrine hydrochloride, d-tubocurarine (Sigma, U.S.A.); ketoconazole (RBI, U.S.A.); synthetic charybdotoxin, scyllatoxin (Latoxan, France); indomethacin (Confortid®, Dumex, Denmark); ciclazindol (Pfizer, U.K.); UCL 1684 (Prof Robert Ganellin; Department of Chemistry, University College London, U.K.); 2-chlorophenyl-bisphenyl-methanol (Dr Carlo Brugnara; brugnara@a1.tch.harvard.edu).

Techniques: Control

Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), ciclazindol (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).

Journal:

Article Title: Effects of inhibitors of small- and intermediate-conductance calcium-activated potassium channels, inwardly-rectifying potassium channels and Na + /K + ATPase on EDHF relaxations in the rat hepatic artery

doi: 10.1038/sj.bjp.0703226

Figure Lengend Snippet: Effects of K+ channel inhibitors on calcium ionophore stimulated 86Rb+ influx in human erythrocytes. The K+ channel inhibitors iberiotoxin (IbTx), apamin (Apa), charybdotoxin (ChTx), ciclazindol (Cz), clotrimazole (CLT) and 2-chlorophenyl-bisphenyl-methanol (C23) and the cytochrome P450 mono-oxygenase inhibitor ketoconazole (KEC) were present 85 min before erythrocytes were stimulated for 5 min by A23187 and Ca2+. Data are expressed as percentage of 86Rb+ influx in the absence of test drugs (control) and are presented as means±s.e.mean of six experiments (all from different individuals). Asterisks denote a statistically significant difference from control values (P<0.05).

Article Snippet: Inhibitors of IK Ca such as charybdotoxin, clotrimazole, 2-chlorophenyl-bisphenyl-methanol and possibly ciclazindol also inhibit BK Ca ( Rittenhouse et al ., 1997a ).

Techniques: Control