Journal: Frontiers in Microbiology

Article Title: Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (vis+wIRA) and Chlorine e6 (Ce6) Eradicates Planktonic Periodontal Pathogens and Subgingival Biofilms

doi: 10.3389/fmicb.2016.01900

Figure Lengend Snippet: Diagrams of the CFUs depicting the photodynamic efficiency against aerobic and anaerobic oral bacteria within the subgingival biofilm, respectively. Ce6 at a concentration of 100 μg/ml served as the photosensitizer. An untreated negative control and a 0.2% CHX-treated positive control were also tested, along with Ce6-treated biofilms in the absence of vis+wIRA and vis+wIRA-treated biofilms in the absence of Ce6. The CFUs are presented on a Log 10 scale per milliliter (Log 10 /ml). Data shown are means ± SD ( n = 6).

Article Snippet: The photosensitizer used was Ce6 (C 34 H 36 N 4 O 6 , Apocare Pharma GmbH, Bielefeld, Germany).

Techniques: Bacteria, Concentration Assay, Negative Control, Positive Control

Journal: Frontiers in Microbiology

Article Title: Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (vis+wIRA) and Chlorine e6 (Ce6) Eradicates Planktonic Periodontal Pathogens and Subgingival Biofilms

doi: 10.3389/fmicb.2016.01900

Figure Lengend Snippet: Boxplots illustrating percentages of the live bacteria as detected by live/dead staining after the application of photodynamic therapy against the subgingival biofilm. Ce6 at a concentration of 100 μg/ml served as the photosensitizer. An untreated negative control and a 0.2% CHX-treated positive control were also tested, along with Ce6-treated biofilms in the absence of vis+wIRA and vis+wIRA-treated biofilms in the absence of Ce6. The central line represents the median; whiskers indicate minimum and maximum.

Article Snippet: The photosensitizer used was Ce6 (C 34 H 36 N 4 O 6 , Apocare Pharma GmbH, Bielefeld, Germany).

Techniques: Bacteria, Staining, Concentration Assay, Negative Control, Positive Control

Journal: Journal of Nanobiotechnology

Article Title: Hemin-incorporating DNA nanozyme enabling catalytic oxygenation and GSH depletion for enhanced photodynamic therapy and synergistic tumor ferroptosis

doi: 10.1186/s12951-022-01617-0

Figure Lengend Snippet: Schematical showing the preparation of DF with AS1411 G4 motif for Ce6 loading and hemin incorporation for tumor targeting PDT/ferroptosis combinatorial therapy

Article Snippet: Hemin and Chlorin e6 (Ce6) were purchased from Frontier Scientific Co., Ltd (Utah, USA).

Techniques:

Journal: Journal of Nanobiotechnology

Article Title: Hemin-incorporating DNA nanozyme enabling catalytic oxygenation and GSH depletion for enhanced photodynamic therapy and synergistic tumor ferroptosis

doi: 10.1186/s12951-022-01617-0

Figure Lengend Snippet: A Schematic showing the design of template sequence and the preparation of DF. B The TEM micro-images of DF and CH/DF. C The SEM micro-image of CH/DF. D DLS and E surface charge measurements of DF and CH/DF. Inset: the appearance of the nanoparticles after centrifugation. F The fluorescence spectra of Ce6 before and after loading into DF. G The elemental mapping micro-image of CH/DF

Article Snippet: Hemin and Chlorin e6 (Ce6) were purchased from Frontier Scientific Co., Ltd (Utah, USA).

Techniques: Sequencing, Centrifugation, Fluorescence

Journal: Journal of Nanobiotechnology

Article Title: Hemin-incorporating DNA nanozyme enabling catalytic oxygenation and GSH depletion for enhanced photodynamic therapy and synergistic tumor ferroptosis

doi: 10.1186/s12951-022-01617-0

Figure Lengend Snippet: A Ex vivo imaging the biodistribution of CH/DF and free Ce6 at 12 h post-injection into tumor bearing mice. B The intensity quantification at different organs based on the fluorescence images in A . C Dynamic monitoring the tumor growth after various treatments. D The appearance and E weight of the tumors at day 16 post various treatments. F Tumor H&E staining images, fluorescent staining of TUNEL and caspase-3 of the mice with different treatments

Article Snippet: Hemin and Chlorin e6 (Ce6) were purchased from Frontier Scientific Co., Ltd (Utah, USA).

Techniques: Ex Vivo, Imaging, Injection, Fluorescence, Staining, TUNEL Assay