Journal: Nanomaterials

Article Title: ToxTracker Reporter Cell Lines as a Tool for Mechanism-Based (Geno)Toxicity Screening of Nanoparticles—Metals, Oxides and Quantum Dots

doi: 10.3390/nano10010110

Figure Lengend Snippet: Summary of primary particle size, approximated particle morphology and main surface oxide composition of the metal and metal oxide NPs based on XRD, Raman and XPS measurements. See Figures S1–S3 and supporting information for surface analytical findings supporting the compositional analysis of the outermost surface oxide.

Article Snippet: The CdTe QDs (1.5–8.6 nm) were purchased from PlasmaChem GmbH (Berlin, Germany).

Techniques:

Journal: Nanomaterials

Article Title: ToxTracker Reporter Cell Lines as a Tool for Mechanism-Based (Geno)Toxicity Screening of Nanoparticles—Metals, Oxides and Quantum Dots

doi: 10.3390/nano10010110

Figure Lengend Snippet: Oxidative stress GFP-reporter activation in response to CdTe QDs of various sizes and CdCl 2 . ToxTracker reporter activation in live cells was measured as GFP-fluorescence using flow cytometry. The Srxn1-GFP reporter is Nrf2-associated, while the Blvrb is Nrf2-independent. The results are presented as mean ± standard error of the mean of three or four independent experiments ( n = 3–4).

Article Snippet: The CdTe QDs (1.5–8.6 nm) were purchased from PlasmaChem GmbH (Berlin, Germany).

Techniques: Activation Assay, Fluorescence, Flow Cytometry

Journal: Nanomaterials

Article Title: ToxTracker Reporter Cell Lines as a Tool for Mechanism-Based (Geno)Toxicity Screening of Nanoparticles—Metals, Oxides and Quantum Dots

doi: 10.3390/nano10010110

Figure Lengend Snippet: Protein and general cellular stress GFP-reporter activation in response to CdTe QDs of various sizes and CdCl 2 . ToxTracker reporter activation in live cells was measured as GFP-fluorescence using flow cytometry. The Ddit3-GFP and Btg2-GFP indicate unfolded protein response or p53-associated cellular stress, respectively. The results are presented as mean ± standard error of the mean of three or four independent experiments ( n = 3–4).

Article Snippet: The CdTe QDs (1.5–8.6 nm) were purchased from PlasmaChem GmbH (Berlin, Germany).

Techniques: Activation Assay, Fluorescence, Flow Cytometry

Journal: Nanomaterials

Article Title: ToxTracker Reporter Cell Lines as a Tool for Mechanism-Based (Geno)Toxicity Screening of Nanoparticles—Metals, Oxides and Quantum Dots

doi: 10.3390/nano10010110

Figure Lengend Snippet: Equi-response curves for CdTe QDs (1.5, 2.6, 4.5, 6.5, 8.6 nm) representing a 20% reduction in cell viability compared to control for Srxn1 and Rtkn reporter. Slopes are plotted according to the model proposed by Delmaar et al. where N denotes the number of particles and d the diameter of the particle.

Article Snippet: The CdTe QDs (1.5–8.6 nm) were purchased from PlasmaChem GmbH (Berlin, Germany).

Techniques:

Journal: Nanomaterials

Article Title: ToxTracker Reporter Cell Lines as a Tool for Mechanism-Based (Geno)Toxicity Screening of Nanoparticles—Metals, Oxides and Quantum Dots

doi: 10.3390/nano10010110

Figure Lengend Snippet: Viability in mES cells following 24 h exposure to CdTe QDs of varying sizes at doses expressed as surface area (cm 2 /mL). Cytotoxicity was determined by measuring the fraction of intact cells following exposure using flow cytometry. The results are presented as mean ± standard error of the mean of three or four independent experiments ( n = 3–4).

Article Snippet: The CdTe QDs (1.5–8.6 nm) were purchased from PlasmaChem GmbH (Berlin, Germany).

Techniques: Flow Cytometry

Journal: Analytical and Bioanalytical Chemistry

Article Title: Chemometrically driven multiplexed metal ion detection using a triple emitting quantum dots–based nanoprobe

doi: 10.1007/s00216-024-05661-7

Figure Lengend Snippet: a PL spectra and b fluorescence images (under a 365-nm UV lamp) of CDs (i), GSH-CdTe QDs (ii), MPA-CdTe QDs (iii), and combined nanoprobe (iv)

Article Snippet: The obtained CdTe QDs underwent precipitation in absolute ethanol (C 2 H 5 OH, 99.8%, Panreac, Barcelona, Spain) to eliminate excess reactants.

Techniques: Fluorescence

Journal: Analytical and Bioanalytical Chemistry

Article Title: Chemometrically driven multiplexed metal ion detection using a triple emitting quantum dots–based nanoprobe

doi: 10.1007/s00216-024-05661-7

Figure Lengend Snippet: a PL spectra of the triple-emitting QDs-based nanoprobe during 60 min. b PL emission intensity evolution throughout 60 min for CDs (blue circle), GSH-CdTe (green circle), and MPA-CdTe (red circle) QDs

Article Snippet: The obtained CdTe QDs underwent precipitation in absolute ethanol (C 2 H 5 OH, 99.8%, Panreac, Barcelona, Spain) to eliminate excess reactants.

Techniques:

Journal: Frontiers in Toxicology

Article Title: Influence of different functionalized CdTe quantum dots on the accumulation of metals, developmental toxicity and respiration in different development stages of the zebrafish ( Danio rerio )

doi: 10.3389/ftox.2023.1176172

Figure Lengend Snippet: Hydrodynamic size (nm) distribution, zeta potential (mV) and metal concentrations (mg/L) of CdTe QDs in E3 media (±SD) measured at the North-West University.

Article Snippet: Characterization of 100 mg/L stock CdTe QDs data were obtained from the Nanosolutions project data sheets since they were the same batches that were used in this study ( ; ; ).

Techniques: Zeta Potential Analyzer, Concentration Assay