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Image Search Results
Journal: Cells
Article Title: Pharmacological Evidence of the Important Roles of CCR1 and CCR3 and Their Endogenous Ligands CCL2/7/8 in Hypersensitivity Based on a Murine Model of Neuropathic Pain
doi: 10.3390/cells12010098
Figure Lengend Snippet: Time-dependent changes in CCL2, CCL3, CCL4, CCL5, CCL6, CCL7, CCL8, CCL9, CCL11, CCL24, CCL26 and CCL28 mRNA levels ( A – L ) in male mice on the 2nd, 7th, 14th and 28th days after chronic constriction injury of the sciatic nerve in the spinal cord. The RT–qPCR data are presented as the fold change of control ± SEMs. Intergroup differences were analyzed using one-way ANOVA with Bonferroni’s post hoc test for multiple comparisons. * p < 0.05, ** p < 0.01, and *** p < 0.001 indicate a significant difference compared with the control group (naive). @ p < 0.05, @@ p < 0.01, and @@@ p < 0.001 indicate differences between the 2nd vs. 7th, 2nd vs. 14th, 2nd vs. 28th, 7th vs. 14th, 7th vs. 28th, and 14th vs. 28th days. The quantity of animals used in the experiment was as follows: RT-qPCR: N ( n = 5–7), 2d ( n = 8), 7d ( n = 8–10), 14d ( n = 10), 28d ( n = 8–9). Abbreviations: N—naive.
Article Snippet: The following TaqMan primers were used: CCL2 (Mm00441243_g1), CCL3 (Mm00441258_m1), CCL4 (Mm00443112_m1), CCL5 (Mm01302428_m1), CCL6 (Mm01302419_m1), CCL7 (Mm01308393_g1), CCL8 (Mm01297183_m1), CCL9 (Mm00441262_g1), CCL11 (Mm00441238_m1), CCL24 (Mm00444701_m1), CCL26 (
Techniques: Quantitative RT-PCR, Control