Journal: iScience

Article Title: Elabela inhibits TRAF1/NF-κB induced oxidative DNA damage to promote diabetic foot ulcer wound healing

doi: 10.1016/j.isci.2023.107601

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Article Snippet: rabbit anti-p21 , Proteintech , Cat# 10335-1-AP.

Techniques: Recombinant, Enzyme-linked Immunosorbent Assay, Plasmid Preparation, Software, Extraction

Journal: Scientific Reports

Article Title: Release of a liver anticancer drug, sorafenib from its PVA/LDH- and PEG/LDH-coated iron oxide nanoparticles for drug delivery applications

doi: 10.1038/s41598-020-76504-5

Figure Lengend Snippet: X-ray diffraction patterns for ( A ) iron oxide nanoparticles; ( B ) MLDH; ( C ) pure sorafenib; ( D ) pure PEG; ( E ) core–shell nanoparticles (FPEGSO-MLDH); ( F ) pure PVA; ( G ) core–shell nanoparticles (FPVASO-MLDH). Inset shows the XRD patterns of ( H ) FPEGSO and ( I ) FPVASO.

Article Snippet: Sorafenib (C 21 H 16 ClF 3 N 4 O 3 ) was sourced from Xi'an Yiyang Bio-Tech (China) at 98.5% purity.

Techniques:

Journal: Scientific Reports

Article Title: Release of a liver anticancer drug, sorafenib from its PVA/LDH- and PEG/LDH-coated iron oxide nanoparticles for drug delivery applications

doi: 10.1038/s41598-020-76504-5

Figure Lengend Snippet: Fourier transform infrared spectra for ( A ) iron oxide nanoparticles; ( B ) MLDH; ( C ) pure sorafenib; ( D ) pure PVA; ( E ) core–shell nanoparticles (FPVASO-MLDH); ( F ) pure PEG; ( G ) core–shell nanoparticles (FPEGSO-MLDH). Inset shows the FTIR spectra of ( H ) FPEGSO and ( I ) FPVASO.

Article Snippet: Sorafenib (C 21 H 16 ClF 3 N 4 O 3 ) was sourced from Xi'an Yiyang Bio-Tech (China) at 98.5% purity.

Techniques:

Journal: Scientific Reports

Article Title: Release of a liver anticancer drug, sorafenib from its PVA/LDH- and PEG/LDH-coated iron oxide nanoparticles for drug delivery applications

doi: 10.1038/s41598-020-76504-5

Figure Lengend Snippet: Release profiles of sorafenib from its physical mixtures ( A ) FPEGSO-MLDH; ( B ) FPVASO-MLDH in phosphate-buffered solution at pH 4.8; ( C ) FPEGSO-MLDH; ( D ) FPVASO-MLDH in phosphate-buffered solution at pH 7.4.

Article Snippet: Sorafenib (C 21 H 16 ClF 3 N 4 O 3 ) was sourced from Xi'an Yiyang Bio-Tech (China) at 98.5% purity.

Techniques:

Journal: Scientific Reports

Article Title: Release of a liver anticancer drug, sorafenib from its PVA/LDH- and PEG/LDH-coated iron oxide nanoparticles for drug delivery applications

doi: 10.1038/s41598-020-76504-5

Figure Lengend Snippet: Sorafenib release profiles from ( A ) FPEGSO-MLDH; ( B ) FPVASO-MLDH in phosphate-buffered solution at pH 4.8; ( C ) FPEGSO-MLDH; ( D ) FPVASO-MLDH in phosphate-buffered solution at pH 7.4.

Article Snippet: Sorafenib (C 21 H 16 ClF 3 N 4 O 3 ) was sourced from Xi'an Yiyang Bio-Tech (China) at 98.5% purity.

Techniques:

Journal: Scientific Reports

Article Title: Release of a liver anticancer drug, sorafenib from its PVA/LDH- and PEG/LDH-coated iron oxide nanoparticles for drug delivery applications

doi: 10.1038/s41598-020-76504-5

Figure Lengend Snippet: The correlation coefficient, rate constant and half-life obtained by fitting the sorafenib release data into the PBS solution at pH 4.8 and pH 7.4.

Article Snippet: Sorafenib (C 21 H 16 ClF 3 N 4 O 3 ) was sourced from Xi'an Yiyang Bio-Tech (China) at 98.5% purity.

Techniques: Diffusion-based Assay

Journal: Scientific Reports

Article Title: Release of a liver anticancer drug, sorafenib from its PVA/LDH- and PEG/LDH-coated iron oxide nanoparticles for drug delivery applications

doi: 10.1038/s41598-020-76504-5

Figure Lengend Snippet: Fitting the data for sorafenib release from ( A ) FPEGSO-MLDH nanoparticles; ( B ) FPVASO-MLDH nanoparticles dissolved in dimethyl sulfoxide into different solutions to the pseudo-second-order kinetics for pH 7.4; ( C ) FPEGSO-MLDH nanoparticles; ( D ) FPVASO-MLDH nanoparticles dissolved in dimethyl sulfoxide into different solutions to the pseudo-second-order kinetics for pH 4.8. Abbreviations: t, time; q t , release at time t.

Article Snippet: Sorafenib (C 21 H 16 ClF 3 N 4 O 3 ) was sourced from Xi'an Yiyang Bio-Tech (China) at 98.5% purity.

Techniques:

Journal: Scientific Reports

Article Title: Release of a liver anticancer drug, sorafenib from its PVA/LDH- and PEG/LDH-coated iron oxide nanoparticles for drug delivery applications

doi: 10.1038/s41598-020-76504-5

Figure Lengend Snippet: Cytotoxicity assay of Sorafenib (SO), FPEG-MLDH, FPVA-MLDH, FPEGSO-MLDH and FPVASO-MLDH against normal 3T3 cells at 72 h. Results were calculated as mean ± standard deviation for n = 3 independent experiments. * p < 0.05 compared to control (untreated cells) and treatment group using the ANOVA and Duncan’s Multiple Range Test.

Article Snippet: Sorafenib (C 21 H 16 ClF 3 N 4 O 3 ) was sourced from Xi'an Yiyang Bio-Tech (China) at 98.5% purity.

Techniques: Cytotoxicity Assay, Standard Deviation

Journal: Scientific Reports

Article Title: Release of a liver anticancer drug, sorafenib from its PVA/LDH- and PEG/LDH-coated iron oxide nanoparticles for drug delivery applications

doi: 10.1038/s41598-020-76504-5

Figure Lengend Snippet: Cytotoxicity assay of sorafenib (SO), FPEG-MLDH, FPVA-MLDH, FPEGSO-MLDH and FPVASO-MLDH against HepG2 cells at 72 h of incubation. Results were calculated as mean ± standard deviation for n = 3 independent experiments. * p < 0.05 compared to control (untreated cells) and treatment group using the ANOVA and Duncan’s Multiple Range Test.

Article Snippet: Sorafenib (C 21 H 16 ClF 3 N 4 O 3 ) was sourced from Xi'an Yiyang Bio-Tech (China) at 98.5% purity.

Techniques: Cytotoxicity Assay, Incubation, Standard Deviation

Journal: Scientific Reports

Article Title: Release of a liver anticancer drug, sorafenib from its PVA/LDH- and PEG/LDH-coated iron oxide nanoparticles for drug delivery applications

doi: 10.1038/s41598-020-76504-5

Figure Lengend Snippet: The half-maximal inhibitory concentration (IC 50 ) value for sorafenib (SO), FPEG-MLDH, FPVA-MLDH, FPEGSO-MLDH, and FPVASO-MLDH samples tested on 3T3 and HepG2 cell lines.

Article Snippet: Sorafenib (C 21 H 16 ClF 3 N 4 O 3 ) was sourced from Xi'an Yiyang Bio-Tech (China) at 98.5% purity.

Techniques: Concentration Assay