bs-10311R Search Results


rabbit anti lxrα  (Bioss)
94
Bioss rabbit anti lxrα
DNLA suppresses <t>LXRα</t> and IDOL protein expression in HepG2 cells. (A) Protein expression of LXRα and IDOL in HepG2 cells was assessed by western blotting. Normalized intensity of (B) LXRα and (C) IDOL vs. GAPDH, presented as the mean ± SD of three independent experiments. * P<0.05, ** P<0.01 and **** P<0.0001. DNLA, Dendrobium nobile Lindl. alkaloids; LPS, lipopolysaccharides; LXRα, liver X receptor α; IDOL, inducible degrader of the low-density lipoprotein receptor.
Rabbit Anti Lxrα, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rabbit anti lxrα - by Bioz Stars, 2026-02
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DNLA suppresses LXRα and IDOL protein expression in HepG2 cells. (A) Protein expression of LXRα and IDOL in HepG2 cells was assessed by western blotting. Normalized intensity of (B) LXRα and (C) IDOL vs. GAPDH, presented as the mean ± SD of three independent experiments. * P<0.05, ** P<0.01 and **** P<0.0001. DNLA, Dendrobium nobile Lindl. alkaloids; LPS, lipopolysaccharides; LXRα, liver X receptor α; IDOL, inducible degrader of the low-density lipoprotein receptor.

Journal: Experimental and Therapeutic Medicine

Article Title: Dendrobium nobile Lindl. alkaloids improve lipid metabolism by increasing LDL uptake through regulation of the LXRα/IDOL/LDLR pathway and inhibition of PCSK9 expression in HepG2 cells

doi: 10.3892/etm.2025.12796

Figure Lengend Snippet: DNLA suppresses LXRα and IDOL protein expression in HepG2 cells. (A) Protein expression of LXRα and IDOL in HepG2 cells was assessed by western blotting. Normalized intensity of (B) LXRα and (C) IDOL vs. GAPDH, presented as the mean ± SD of three independent experiments. * P<0.05, ** P<0.01 and **** P<0.0001. DNLA, Dendrobium nobile Lindl. alkaloids; LPS, lipopolysaccharides; LXRα, liver X receptor α; IDOL, inducible degrader of the low-density lipoprotein receptor.

Article Snippet: Subsequently, the membranes were blocked with 5% skimmed dry milk in Tris-buffer solution with 0.1% Tween-20 (TBST) at room temperature for 2 h before being incubated overnight at 4˚C with the following primary antibodies (1:1,000): Rabbit anti-LDLR (cat. no. ab30532; Abcam), rabbit anti-PCSK9 (cat. no. ab185194; Abcam), rabbit anti-IDOL (cat. no. bs-9674R; BIOSS), rabbit anti-SREBP2 (cat. no. ab30682; Abcam), rabbit anti-LXRα (cat. no. bs-10311R; BIOSS), rabbit anti-HNF1α (cat. no. 89670S; Cell Signaling Technology, Inc.), rabbit anti-3-hydroxy-3-methyl glutaryl-coenzyme A reductase (HMGCR; cat. no. ab242315; Abcam), rabbit anti-cytochrome P450 (CYP) 7A1 (cat. no. bs-21430R; BIOSS) and mouse anti-GAPDH (cat. no. 97166S; Cell Signaling Technology, Inc.).

Techniques: Expressing, Western Blot

T0901317, an LXRα agonist, reverses the decrease in IDOL and LXRα expression induced by DNLA and reduces the LDLR content in HepG2 cells. (A) Protein expression of LXRα, IDOL and LDLR in HepG2 cells assessed by western blotting. Normalized intensity of (B) LXRα, (C) IDOL and (D) LDLR vs. GAPDH, presented as the mean ± SD of three independent experiments. * P<0.05, ** P<0.01, *** P<0.001 and **** P<0.0001. DNLA, Dendrobium nobile Lindl. alkaloids; LPS, lipopolysaccharides; LXRα, liver X receptor α; IDOL, inducible degrader of the low-density lipoprotein receptor; LDLR, low-density lipoprotein receptor.

Journal: Experimental and Therapeutic Medicine

Article Title: Dendrobium nobile Lindl. alkaloids improve lipid metabolism by increasing LDL uptake through regulation of the LXRα/IDOL/LDLR pathway and inhibition of PCSK9 expression in HepG2 cells

doi: 10.3892/etm.2025.12796

Figure Lengend Snippet: T0901317, an LXRα agonist, reverses the decrease in IDOL and LXRα expression induced by DNLA and reduces the LDLR content in HepG2 cells. (A) Protein expression of LXRα, IDOL and LDLR in HepG2 cells assessed by western blotting. Normalized intensity of (B) LXRα, (C) IDOL and (D) LDLR vs. GAPDH, presented as the mean ± SD of three independent experiments. * P<0.05, ** P<0.01, *** P<0.001 and **** P<0.0001. DNLA, Dendrobium nobile Lindl. alkaloids; LPS, lipopolysaccharides; LXRα, liver X receptor α; IDOL, inducible degrader of the low-density lipoprotein receptor; LDLR, low-density lipoprotein receptor.

Article Snippet: Subsequently, the membranes were blocked with 5% skimmed dry milk in Tris-buffer solution with 0.1% Tween-20 (TBST) at room temperature for 2 h before being incubated overnight at 4˚C with the following primary antibodies (1:1,000): Rabbit anti-LDLR (cat. no. ab30532; Abcam), rabbit anti-PCSK9 (cat. no. ab185194; Abcam), rabbit anti-IDOL (cat. no. bs-9674R; BIOSS), rabbit anti-SREBP2 (cat. no. ab30682; Abcam), rabbit anti-LXRα (cat. no. bs-10311R; BIOSS), rabbit anti-HNF1α (cat. no. 89670S; Cell Signaling Technology, Inc.), rabbit anti-3-hydroxy-3-methyl glutaryl-coenzyme A reductase (HMGCR; cat. no. ab242315; Abcam), rabbit anti-cytochrome P450 (CYP) 7A1 (cat. no. bs-21430R; BIOSS) and mouse anti-GAPDH (cat. no. 97166S; Cell Signaling Technology, Inc.).

Techniques: Expressing, Western Blot