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Image Search Results
Journal: JCI Insight
Article Title: Stem cell–associated osteogenic deficiency causes craniofacial deformities with progeroid accumulation of prelamin A
doi: 10.1172/jci.insight.196932
Figure Lengend Snippet: ( A ) Limiting dilution analysis of stem cell–mediated bone formation with renal capsule transplantation. Representative images of whole-mount von Kossa staining detecting ectopic bone formation in the mouse recipients transplanted by the indicated number of suture cells into the renal capsule. Arrowheads indicate the ectopic bones. ( B ) Representative images showing the analysis of Axin2-expressing cells using the Axin2 mGFP allele in the indicated 1-month-old (1M) suture. ( C ) Representative images examining the BMPR1A + and GLI1 + cell population within the indicated 1-month-old (1M) suture. ( D ) Graphs indicate the quantitation of the average percentage of BMPR1A + and GLI1 + cells in 3 independent experiments ( P < 0.005 or 0.05, n = 3, mean ± SEM, 2-tailed Student’s t test). SAG, sagittal; COR, coronal; AF, anterior frontal. Scale bars: 1 mm ( A ) and 50 μm ( B and C ).
Article Snippet:
Techniques: Transplantation Assay, Staining, Expressing, Quantitation Assay