bml 260 sc 223822a Search Results


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    • bml 260 sc 223822a  (Santa Cruz Biotechnology)
    92
    Santa Cruz Biotechnology bml 260 sc 223822a
    Reduced cancer cell invasion and metastasis in vivo by inhibition of DUSP22 . ( a ) Inhibitory effect of DUSP22 targeting drug <t>BML-260</t> on the invasion assay of RECNA RCC cells cocultured with RAW264.7 macrophages. Scale bar = 100 μm. ( b ) Schematic of the protocol to investigate the effect of macrophage DUSP22 inhibition on dissemination (early stage of metastasis) in cotransplanted RCC in vivo. ( c ) Representative microscopic images of fish larvae post-transplantation and the RCC dissemination rate with RCC alone ( n = 39) or cotransplanted with DMSO-treated macrophages ( n = 39) or BML-260-treated macrophages ( n = 44). Disseminated RCC cells were visualized by labelling with DiI. Arrows indicate tumor foci disseminated from the injection site (yolk sac). Scale bar = 100 μm.
    Bml 260 Sc 223822a, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/bml 260 sc 223822a/product/Santa Cruz Biotechnology
    Average 92 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    bml 260 sc 223822a - by Bioz Stars, 2024-10
    92/100 stars
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    Image Search Results


    Reduced cancer cell invasion and metastasis in vivo by inhibition of DUSP22 . ( a ) Inhibitory effect of DUSP22 targeting drug BML-260 on the invasion assay of RECNA RCC cells cocultured with RAW264.7 macrophages. Scale bar = 100 μm. ( b ) Schematic of the protocol to investigate the effect of macrophage DUSP22 inhibition on dissemination (early stage of metastasis) in cotransplanted RCC in vivo. ( c ) Representative microscopic images of fish larvae post-transplantation and the RCC dissemination rate with RCC alone ( n = 39) or cotransplanted with DMSO-treated macrophages ( n = 39) or BML-260-treated macrophages ( n = 44). Disseminated RCC cells were visualized by labelling with DiI. Arrows indicate tumor foci disseminated from the injection site (yolk sac). Scale bar = 100 μm.

    Journal: Cancers

    Article Title: Genome-Wide Transcriptomic Analysis of Non-Tumorigenic Tissues Reveals Aging-Related Prognostic Markers and Drug Targets in Renal Cell Carcinoma

    doi: 10.3390/cancers13123045

    Figure Lengend Snippet: Reduced cancer cell invasion and metastasis in vivo by inhibition of DUSP22 . ( a ) Inhibitory effect of DUSP22 targeting drug BML-260 on the invasion assay of RECNA RCC cells cocultured with RAW264.7 macrophages. Scale bar = 100 μm. ( b ) Schematic of the protocol to investigate the effect of macrophage DUSP22 inhibition on dissemination (early stage of metastasis) in cotransplanted RCC in vivo. ( c ) Representative microscopic images of fish larvae post-transplantation and the RCC dissemination rate with RCC alone ( n = 39) or cotransplanted with DMSO-treated macrophages ( n = 39) or BML-260-treated macrophages ( n = 44). Disseminated RCC cells were visualized by labelling with DiI. Arrows indicate tumor foci disseminated from the injection site (yolk sac). Scale bar = 100 μm.

    Article Snippet: BML-260(sc-223822A) was purchased from Santa Cruz Biotechnology (Dallas, TX, USA).

    Techniques: In Vivo, Inhibition, Invasion Assay, Transplantation Assay, Injection