app 695 Search Results


amyloid precursor/app-695, human  (MedChemExpress)
N/A
Amyloid Precursor/APP-695 Protein, Human (HEK293, Fc) is an Amyloid Precursor (APP) protein with C-Fc. Amyloid Precursor Protein can be used for the study of brain development, learning and memory, synaptic plasticity, and neurodegeneration.
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amyloid precursor protein app  (Addgene inc)
93
Addgene inc amyloid precursor protein app
(A) Representative Western Blots of Aβ and IDE in neuronal cells after <t>APP</t> transfection. (B) sPIF reduces Aβ formation in IDE dependent manner. (C) Identified regions of structural similarity within the set of protein structures by STRALCP. Clustering of structurally conserved fragments ( left ). STRALCP identified structural similarity between selected “ reference ” structure and other analyzed structures, represented as colored bars, based on C alpha - C alpha distance deviation at each position between the reference (top bar) and other structures ( right ). The colors indicate RMSD between aligned residues, ranging from green (below 2Å), yellow (below 4Å), orange (below 6Å), to red (above 6Å). STRALCP: STRucture ALignment-based Clustering of Proteins; RMSD: Room mean square distances; Aβ: Amyloid Beta; IDE: Insulin degrading enzyme; APP: <t>Amyloid</t> <t>precursor</t> protein; sPIF: synthetic PreImplantation Factor; * p<0.05; ** p<0.01; *** p<0.001 (ANOVA followed by two tail t test). In-vitro experiment results represent at least three independent experiments.
Amyloid Precursor Protein App, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/app+695/pCAX+APP+695+(Plasmid+%2330137)/pmc06188057-172-4-9
Average 93 stars, based on 1 article reviews
amyloid precursor protein app - by Bioz Stars, 2026-09
93/100 stars
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tg2576 mice expressing the swedish mutation of human app 695  (McLaughlin Research Corporation)
90
McLaughlin Research Corporation tg2576 mice expressing the swedish mutation of human app 695
(A) Representative Western Blots of Aβ and IDE in neuronal cells after <t>APP</t> transfection. (B) sPIF reduces Aβ formation in IDE dependent manner. (C) Identified regions of structural similarity within the set of protein structures by STRALCP. Clustering of structurally conserved fragments ( left ). STRALCP identified structural similarity between selected “ reference ” structure and other analyzed structures, represented as colored bars, based on C alpha - C alpha distance deviation at each position between the reference (top bar) and other structures ( right ). The colors indicate RMSD between aligned residues, ranging from green (below 2Å), yellow (below 4Å), orange (below 6Å), to red (above 6Å). STRALCP: STRucture ALignment-based Clustering of Proteins; RMSD: Room mean square distances; Aβ: Amyloid Beta; IDE: Insulin degrading enzyme; APP: <t>Amyloid</t> <t>precursor</t> protein; sPIF: synthetic PreImplantation Factor; * p<0.05; ** p<0.01; *** p<0.001 (ANOVA followed by two tail t test). In-vitro experiment results represent at least three independent experiments.
Tg2576 Mice Expressing The Swedish Mutation Of Human App 695, supplied by McLaughlin Research Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/app+695/tg2576+mice+expressing+the+swedish+mutation+of+human+app+695/pmc02909296-45-4-16
Average 90 stars, based on 1 article reviews
tg2576 mice expressing the swedish mutation of human app 695 - by Bioz Stars, 2026-09
90/100 stars
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Image Search Results


(A) Representative Western Blots of Aβ and IDE in neuronal cells after APP transfection. (B) sPIF reduces Aβ formation in IDE dependent manner. (C) Identified regions of structural similarity within the set of protein structures by STRALCP. Clustering of structurally conserved fragments ( left ). STRALCP identified structural similarity between selected “ reference ” structure and other analyzed structures, represented as colored bars, based on C alpha - C alpha distance deviation at each position between the reference (top bar) and other structures ( right ). The colors indicate RMSD between aligned residues, ranging from green (below 2Å), yellow (below 4Å), orange (below 6Å), to red (above 6Å). STRALCP: STRucture ALignment-based Clustering of Proteins; RMSD: Room mean square distances; Aβ: Amyloid Beta; IDE: Insulin degrading enzyme; APP: Amyloid precursor protein; sPIF: synthetic PreImplantation Factor; * p<0.05; ** p<0.01; *** p<0.001 (ANOVA followed by two tail t test). In-vitro experiment results represent at least three independent experiments.

Journal: Oncotarget

Article Title: The core sequence of PIF competes for insulin/amyloid β in insulin degrading enzyme: potential treatment for Alzheimer's disease

doi: 10.18632/oncotarget.26057

Figure Lengend Snippet: (A) Representative Western Blots of Aβ and IDE in neuronal cells after APP transfection. (B) sPIF reduces Aβ formation in IDE dependent manner. (C) Identified regions of structural similarity within the set of protein structures by STRALCP. Clustering of structurally conserved fragments ( left ). STRALCP identified structural similarity between selected “ reference ” structure and other analyzed structures, represented as colored bars, based on C alpha - C alpha distance deviation at each position between the reference (top bar) and other structures ( right ). The colors indicate RMSD between aligned residues, ranging from green (below 2Å), yellow (below 4Å), orange (below 6Å), to red (above 6Å). STRALCP: STRucture ALignment-based Clustering of Proteins; RMSD: Room mean square distances; Aβ: Amyloid Beta; IDE: Insulin degrading enzyme; APP: Amyloid precursor protein; sPIF: synthetic PreImplantation Factor; * p<0.05; ** p<0.01; *** p<0.001 (ANOVA followed by two tail t test). In-vitro experiment results represent at least three independent experiments.

Article Snippet: We purchased plasmids containing amyloid precursor protein (APP) from Addgene (pCAX APP 695 #30137).

Techniques: Western Blot, Transfection, In Vitro