ag879 Search Results


93
MedChemExpress ag879
Chemical structures of RTK inhibitors <t>AG879,</t> Lapatinib, Gefitinib, and GW441756 ( A ). Timeline of infection, treatment, and viral collection ( B ). SARS-CoV-2 replication in cells pre-treated with RTK inhibitors. A549-ACE2 (top panels) and Vero-E6 (bottom panels) were treated for 30 min and then infected with SARS-CoV-2 (WA1) at an MOI = 0.01. Supernatants were collected, and viral particles were quantified by measuring viral RNA via RT-qPCR ( C ) and infectious particles via a plaque assay ( D ). Viral RNA levels in the infected cells were quantified by RT-qPCR ( E ). ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.
Ag879, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ag879/Tyrphostin+AG+879/pmc12030552-42-0-1
Average 93 stars, based on 1 article reviews
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N/A
TyrphostinAG879 (Cat.No:I001825) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation, but not TrKB and TrKC.[1] also a ErbB2 kinase inhibitor, has at least 500-fold higher selectivity to ErbB2 (IC50 = 1 μmol/L) than EGFR
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91
Selleck Chemicals tyrphostin ag879
Chemical structures of RTK inhibitors <t>AG879,</t> Lapatinib, Gefitinib, and GW441756 ( A ). Timeline of infection, treatment, and viral collection ( B ). SARS-CoV-2 replication in cells pre-treated with RTK inhibitors. A549-ACE2 (top panels) and Vero-E6 (bottom panels) were treated for 30 min and then infected with SARS-CoV-2 (WA1) at an MOI = 0.01. Supernatants were collected, and viral particles were quantified by measuring viral RNA via RT-qPCR ( C ) and infectious particles via a plaque assay ( D ). Viral RNA levels in the infected cells were quantified by RT-qPCR ( E ). ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.
Tyrphostin Ag879, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ag879/Tyrphostin+AG+879/pmc04500372-135-0-4
Average 91 stars, based on 1 article reviews
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91
Santa Cruz Biotechnology h 290
Chemical structures of RTK inhibitors <t>AG879,</t> Lapatinib, Gefitinib, and GW441756 ( A ). Timeline of infection, treatment, and viral collection ( B ). SARS-CoV-2 replication in cells pre-treated with RTK inhibitors. A549-ACE2 (top panels) and Vero-E6 (bottom panels) were treated for 30 min and then infected with SARS-CoV-2 (WA1) at an MOI = 0.01. Supernatants were collected, and viral particles were quantified by measuring viral RNA via RT-qPCR ( C ) and infectious particles via a plaque assay ( D ). Viral RNA levels in the infected cells were quantified by RT-qPCR ( E ). ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.
H 290, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ag879/Tyrphostin+AG+879/pmc07749161-192-18-20
Average 91 stars, based on 1 article reviews
h 290 - by Bioz Stars, 2026-10
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90
Biomol GmbH tyrphostins ag-879
Chemical structures of RTK inhibitors <t>AG879,</t> Lapatinib, Gefitinib, and GW441756 ( A ). Timeline of infection, treatment, and viral collection ( B ). SARS-CoV-2 replication in cells pre-treated with RTK inhibitors. A549-ACE2 (top panels) and Vero-E6 (bottom panels) were treated for 30 min and then infected with SARS-CoV-2 (WA1) at an MOI = 0.01. Supernatants were collected, and viral particles were quantified by measuring viral RNA via RT-qPCR ( C ) and infectious particles via a plaque assay ( D ). Viral RNA levels in the infected cells were quantified by RT-qPCR ( E ). ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.
Tyrphostins Ag 879, supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ag879/ag879/pm11043579-202-0-7
Average 90 stars, based on 1 article reviews
tyrphostins ag-879 - by Bioz Stars, 2026-10
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Merck KGaA ag879 (inhibitor of erbb2)
Chemical structures of RTK inhibitors <t>AG879,</t> Lapatinib, Gefitinib, and GW441756 ( A ). Timeline of infection, treatment, and viral collection ( B ). SARS-CoV-2 replication in cells pre-treated with RTK inhibitors. A549-ACE2 (top panels) and Vero-E6 (bottom panels) were treated for 30 min and then infected with SARS-CoV-2 (WA1) at an MOI = 0.01. Supernatants were collected, and viral particles were quantified by measuring viral RNA via RT-qPCR ( C ) and infectious particles via a plaque assay ( D ). Viral RNA levels in the infected cells were quantified by RT-qPCR ( E ). ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.
Ag879 (Inhibitor Of Erbb2), supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ag879/cyano+3+5+di+t+butyl+4+hydroxy+thiocinnamide++ag879+/pm32548701-145-4-16
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90
ApexBio trka inhibitor ag879
Chemical structures of RTK inhibitors <t>AG879,</t> Lapatinib, Gefitinib, and GW441756 ( A ). Timeline of infection, treatment, and viral collection ( B ). SARS-CoV-2 replication in cells pre-treated with RTK inhibitors. A549-ACE2 (top panels) and Vero-E6 (bottom panels) were treated for 30 min and then infected with SARS-CoV-2 (WA1) at an MOI = 0.01. Supernatants were collected, and viral particles were quantified by measuring viral RNA via RT-qPCR ( C ) and infectious particles via a plaque assay ( D ). Viral RNA levels in the infected cells were quantified by RT-qPCR ( E ). ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.
Trka Inhibitor Ag879, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ag879/trka+inhibitor+ag879/10__1016_slash_j__matdes__2020__108982-101-9-14
Average 90 stars, based on 1 article reviews
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LC Laboratories ag879
Chemical structures of RTK inhibitors <t>AG879,</t> Lapatinib, Gefitinib, and GW441756 ( A ). Timeline of infection, treatment, and viral collection ( B ). SARS-CoV-2 replication in cells pre-treated with RTK inhibitors. A549-ACE2 (top panels) and Vero-E6 (bottom panels) were treated for 30 min and then infected with SARS-CoV-2 (WA1) at an MOI = 0.01. Supernatants were collected, and viral particles were quantified by measuring viral RNA via RT-qPCR ( C ) and infectious particles via a plaque assay ( D ). Viral RNA levels in the infected cells were quantified by RT-qPCR ( E ). ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.
Ag879, supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ag879/ag879/pm10670437-33-5-12
Average 90 stars, based on 1 article reviews
ag879 - by Bioz Stars, 2026-10
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N/A
NGFR kinase inhibitor
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N/A
Protein tyrosine kinase PTK inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs Tyrphostins are a class of antiproliferative compounds which selectively inhibit PTKs of key growth factors AG 879 is
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Image Search Results


Chemical structures of RTK inhibitors AG879, Lapatinib, Gefitinib, and GW441756 ( A ). Timeline of infection, treatment, and viral collection ( B ). SARS-CoV-2 replication in cells pre-treated with RTK inhibitors. A549-ACE2 (top panels) and Vero-E6 (bottom panels) were treated for 30 min and then infected with SARS-CoV-2 (WA1) at an MOI = 0.01. Supernatants were collected, and viral particles were quantified by measuring viral RNA via RT-qPCR ( C ) and infectious particles via a plaque assay ( D ). Viral RNA levels in the infected cells were quantified by RT-qPCR ( E ). ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.

Journal: Pathogens

Article Title: Cellular Receptor Tyrosine Kinase Signaling Plays Important Roles in SARS-CoV-2 Infection

doi: 10.3390/pathogens14040333

Figure Lengend Snippet: Chemical structures of RTK inhibitors AG879, Lapatinib, Gefitinib, and GW441756 ( A ). Timeline of infection, treatment, and viral collection ( B ). SARS-CoV-2 replication in cells pre-treated with RTK inhibitors. A549-ACE2 (top panels) and Vero-E6 (bottom panels) were treated for 30 min and then infected with SARS-CoV-2 (WA1) at an MOI = 0.01. Supernatants were collected, and viral particles were quantified by measuring viral RNA via RT-qPCR ( C ) and infectious particles via a plaque assay ( D ). Viral RNA levels in the infected cells were quantified by RT-qPCR ( E ). ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.

Article Snippet: AG879 (MedChemExpress, HY-20878, Monmouth Junction, NJ, USA) is a selective inhibitor of both tropomyosin kinase receptor A (TrkA) and human epidermal growth factor receptor 2 (HER2), Lapatinib (Sigma Aldrich, CDS022971, St. Louis, MO, USA) is a reversible inhibitor of both epidermal growth factor receptor (EGFR) and HER2, Gefitinib (Sigma Aldrich, SML1657) is a selective inhibitor of EGFR, and GW441756 (MedChemExpress, HY-18314) is a selective inhibitor of TrkA [ , , ].

Techniques: Infection, Quantitative RT-PCR, Plaque Assay