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Bio-Techne corporation goat anti vegf d
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93
R&D Systems anti mouse vegf mab
Impacts of the implantation of WT mouse– or AT1a–/– mouse–derived MNCs into the ischemic hindlimbs of AT1a–/– mice on angiogenesis. The impaired LDBF ratio in AT1a–/– mice was partially but significantly restored after implantation of WT mouse–derived MNCs into the ischemic hindlimb of AT1a–/– mice (P < 0.01 vs. AT1a–/–). In contrast, implantation of AT1a–/– mouse–derived MNCs slightly improved the LDBF ratio in AT1a–/– mice, but the difference was not significant (vs. <t>AT1a–/–).</t> <t>Neutralizing</t> <t>anti-VEGF</t> mAb treatment abolished the WT-MNC–mediated rescue of impaired angiogenesis in AT1a–/– mice (P = NS vs. AT1a–/–).
Anti Mouse Vegf Mab, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Impacts of the implantation of WT mouse– or AT1a–/– mouse–derived MNCs into the ischemic hindlimbs of AT1a–/– mice on angiogenesis. The impaired LDBF ratio in AT1a–/– mice was partially but significantly restored after implantation of WT mouse–derived MNCs into the ischemic hindlimb of AT1a–/– mice (P < 0.01 vs. AT1a–/–). In contrast, implantation of AT1a–/– mouse–derived MNCs slightly improved the LDBF ratio in AT1a–/– mice, but the difference was not significant (vs. AT1a–/–). Neutralizing anti-VEGF mAb treatment abolished the WT-MNC–mediated rescue of impaired angiogenesis in AT1a–/– mice (P = NS vs. AT1a–/–).

Journal:

Article Title: Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis

doi: 10.1172/JCI13055

Figure Lengend Snippet: Impacts of the implantation of WT mouse– or AT1a–/– mouse–derived MNCs into the ischemic hindlimbs of AT1a–/– mice on angiogenesis. The impaired LDBF ratio in AT1a–/– mice was partially but significantly restored after implantation of WT mouse–derived MNCs into the ischemic hindlimb of AT1a–/– mice (P < 0.01 vs. AT1a–/–). In contrast, implantation of AT1a–/– mouse–derived MNCs slightly improved the LDBF ratio in AT1a–/– mice, but the difference was not significant (vs. AT1a–/–). Neutralizing anti-VEGF mAb treatment abolished the WT-MNC–mediated rescue of impaired angiogenesis in AT1a–/– mice (P = NS vs. AT1a–/–).

Article Snippet: In five additional mice, neutralizing anti-mouse VEGF mAb (R&D Systems Inc., Minneapolis, Minnesota, USA) was continuously administered by a subcutaneously implanted osmotic pump (ALZA Corp.), and ischemia-induced angiogenesis was examined in AT1a –/– mice that had been subjected to WT-derived MNC transplantation.

Techniques: Derivative Assay