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Image Search Results
Journal: Environment international
Article Title: Cresyl diphenyl phosphate (a novel organophosphate ester) induces hepatic steatosis by directly binding to liver X receptor α: From molecule action to risk assessment.
doi: 10.1016/j.envint.2024.109168
Figure Lengend Snippet: Fig. 6. Lipogenesis effects of CDP on mouse liver. a-h 6-week-old mice were intragastric administrated with different dose of CDP (0.1, 1, 10 mg/kg/day) for 12 weeks with corn oil as control treatment (n = 7 per group). (a) H&E and Oil red O staining of liver sections. (b-f) Relative Lxrα, Srebp1c, Acc1, Fasn, and Scd mRNA expression levels in mouse liver. The relative mRNA level was normalized to control group (mice treated with corn oil). *P < 0.05, compared with control. (g) Protein expression of LXRα, SREBP1c, ACC1, FASN, and SCD in mouse liver. (h) Quantitative analysis of protein expression.
Article Snippet: The following antibodies were used in the study: anti-LXRα antibody (Proteintech, catalogue no. 14351-1-AP, diluted 1:5000), anti-SREBP1c antibody (Zen bio, catalogue no. 347061, diluted 1:1000), anti-FASN antibody (Zen bio, catalogue no. 200194, diluted 1:1000),
Techniques: Control, Staining, Expressing