a375-p Search Results


human melanoma cell lines a375p  (ATCC)
95
ATCC human melanoma cell lines a375p
FIGURE 1 – Kinetics of the p53 protein expression (detected by immunoblotting) after UVB 150J/m2 or UVC 50 J/m2 irradiation in p53 wildtype <t>(A375P)</t> and mutant p53 (SK-MEL2 and SK-MEL28) melanoma cells.
Human Melanoma Cell Lines A375p, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a375-p/pm11948456-28-11-26?v=ATCC
Average 95 stars, based on 1 article reviews
human melanoma cell lines a375p - by Bioz Stars, 2026-08
95/100 stars
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a375p beta6-puro cell line  (CancerTools Org)
N/A
The A375P beta6-puro Cell Line is a useful model for studying the function and activity of beta 6 integrin when used as a matched pair with the parent A375 line. A375 melanoma cells endogenously express
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human melanoma cell lines  (ATCC)
92
ATCC human melanoma cell lines
FIGURE 1 – Kinetics of the p53 protein expression (detected by immunoblotting) after UVB 150J/m2 or UVC 50 J/m2 irradiation in p53 wildtype <t>(A375P)</t> and mutant p53 (SK-MEL2 and SK-MEL28) melanoma cells.
Human Melanoma Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a375-p/ppr0122524-56-9-23?v=ATCC
Average 92 stars, based on 1 article reviews
human melanoma cell lines - by Bioz Stars, 2026-08
92/100 stars
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melanoma cell lines a375p  (YOUAI Co Ltd)
90
YOUAI Co Ltd melanoma cell lines a375p
FIGURE 1 – Kinetics of the p53 protein expression (detected by immunoblotting) after UVB 150J/m2 or UVC 50 J/m2 irradiation in p53 wildtype <t>(A375P)</t> and mutant p53 (SK-MEL2 and SK-MEL28) melanoma cells.
Melanoma Cell Lines A375p, supplied by YOUAI Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a375-p/pm25912549-50-0-24?v=YOUAI+Co+Ltd
Average 90 stars, based on 1 article reviews
melanoma cell lines a375p - by Bioz Stars, 2026-08
90/100 stars
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a375sm cell lines  (Korean Cell Line Bank)
86
Korean Cell Line Bank a375sm cell lines
Cyclic mechanical strain engages the same anti-apoptotic pathway in high metastatic human melanoma as in the murine model. (A) Schematic of the experimental workflow translating the murine findings to human melanoma (B) Quantification of caspase-3/7-positive cells after 6 h of cyclic stretch. The apoptotic cell ratio was significantly reduced in the Stretch group compared to the static group in <t>A375SM,</t> whereas it showed a slight increase in A375P (n = 25). (C) Effect of BAX inhibition (BAI1) ± stretch. In A375SM, stretch alone lowers apoptosis more than BAI1 alone, and the combination produces an additional reduction (n = 25). (D) Effect of BCL-2 family inhibition (BH3I1) ± stretch. BH3I1 and stretch individually reduce apoptosis to a similar extent in A375SM, with no further decrease in the combined group (n = 25). (E) Effect of BAD inhibition (NPB) ± stretch. NPB and stretch each lower apoptosis in A375SM, and together yield the greatest suppression (n = 25). (F) Piezo1 inhibition (isoquercetin) raises apoptosis in A375SM irrespective of stretch, indicating a conserved mechano-protective role for Piezo1 (n = 25). (G) qPCR fold change in apoptosis-promoting genes (stretch/static). The response to these genes was blunted in A375SM compared to A375P (n = 3). (H) Fold change of anti-apoptotic genes is greater in A375SM than A375P (n = 3). (I) Fold change of proliferation markers is higher in A375SM, suggesting that caspase-3 activity may be redirected toward growth under mechanical stimulation (n = 3). ∗∗∗p < 0.0005; ∗∗p < 0.005; ∗p < 0.05, based on one-way ANOVA with Tukey HSD post-hoc testing. Error bars represent mean ± SD.
A375sm Cell Lines, supplied by Korean Cell Line Bank, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a375-p/pmc13156779-78-4-11?v=Korean+Cell+Line+Bank
Average 86 stars, based on 1 article reviews
a375sm cell lines - by Bioz Stars, 2026-08
86/100 stars
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a375p  (AcceGen Biotechnology)
N/A
Tumorigenecity: Isoenzyme: Histopathology: melanoma, low metastaticSubculture: Split ratio: Media change: Reverse transcritase: Production.
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Image Search Results


FIGURE 1 – Kinetics of the p53 protein expression (detected by immunoblotting) after UVB 150J/m2 or UVC 50 J/m2 irradiation in p53 wildtype (A375P) and mutant p53 (SK-MEL2 and SK-MEL28) melanoma cells.

Journal: International journal of cancer

Article Title: Specific induction of gadd45 in human melanocytes and melanoma cells after UVB irradiation.

doi: 10.1002/ijc.10275

Figure Lengend Snippet: FIGURE 1 – Kinetics of the p53 protein expression (detected by immunoblotting) after UVB 150J/m2 or UVC 50 J/m2 irradiation in p53 wildtype (A375P) and mutant p53 (SK-MEL2 and SK-MEL28) melanoma cells.

Article Snippet: Normal human melanocytes (NHM) were obtained and cultured as described previously.8 Human melanoma cell lines A375P, WM115, SK-Mel2, SK-Mel28, MeWo and Malme3M were obtained from the American Type Culture Collection.

Techniques: Expressing, Western Blot, Irradiation, Mutagenesis

FIGURE 2 – Effect of UVB (150 J/m2) or UVC (50 J m2) irradiation on the growth of A375P cells. Cells were plated in 24-well plate at a density of 2,500 cells/well. Alamar blue was added in medium 24, 48, 72 and 96 hr after beginning of treatment and fluorescence was read 4 hr later.

Journal: International journal of cancer

Article Title: Specific induction of gadd45 in human melanocytes and melanoma cells after UVB irradiation.

doi: 10.1002/ijc.10275

Figure Lengend Snippet: FIGURE 2 – Effect of UVB (150 J/m2) or UVC (50 J m2) irradiation on the growth of A375P cells. Cells were plated in 24-well plate at a density of 2,500 cells/well. Alamar blue was added in medium 24, 48, 72 and 96 hr after beginning of treatment and fluorescence was read 4 hr later.

Article Snippet: Normal human melanocytes (NHM) were obtained and cultured as described previously.8 Human melanoma cell lines A375P, WM115, SK-Mel2, SK-Mel28, MeWo and Malme3M were obtained from the American Type Culture Collection.

Techniques: Irradiation

FIGURE 3 – Quantitative RT-PCR analysis of mdm2, p21WAF1, cyclin G1, gadd45, bax 16 hr after UVB 150 J/m2 and UVC 50 J/m2 irradiation in A375P melanoma cells. Results for all cells tested are summarized in Tables I and II.

Journal: International journal of cancer

Article Title: Specific induction of gadd45 in human melanocytes and melanoma cells after UVB irradiation.

doi: 10.1002/ijc.10275

Figure Lengend Snippet: FIGURE 3 – Quantitative RT-PCR analysis of mdm2, p21WAF1, cyclin G1, gadd45, bax 16 hr after UVB 150 J/m2 and UVC 50 J/m2 irradiation in A375P melanoma cells. Results for all cells tested are summarized in Tables I and II.

Article Snippet: Normal human melanocytes (NHM) were obtained and cultured as described previously.8 Human melanoma cell lines A375P, WM115, SK-Mel2, SK-Mel28, MeWo and Malme3M were obtained from the American Type Culture Collection.

Techniques: Quantitative RT-PCR, Irradiation

FIGURE 4 – Increase of protein expression of gadd45 (detected by immunoblotting) in M4Be and A375P melanoma cells after UVB irradiation (150J/m2) or UVC irradiation (50J/m2) (NT untreated control).

Journal: International journal of cancer

Article Title: Specific induction of gadd45 in human melanocytes and melanoma cells after UVB irradiation.

doi: 10.1002/ijc.10275

Figure Lengend Snippet: FIGURE 4 – Increase of protein expression of gadd45 (detected by immunoblotting) in M4Be and A375P melanoma cells after UVB irradiation (150J/m2) or UVC irradiation (50J/m2) (NT untreated control).

Article Snippet: Normal human melanocytes (NHM) were obtained and cultured as described previously.8 Human melanoma cell lines A375P, WM115, SK-Mel2, SK-Mel28, MeWo and Malme3M were obtained from the American Type Culture Collection.

Techniques: Expressing, Western Blot, Irradiation, Control

FIGURE 5 – Quantitative RT-PCR analysis of mdm2, p21WAF1, cyclin G1, gadd45, bax 16 hr after UVB treatment with different doses in A375P melanoma cells. Results of quantitative analysis are in Table III.

Journal: International journal of cancer

Article Title: Specific induction of gadd45 in human melanocytes and melanoma cells after UVB irradiation.

doi: 10.1002/ijc.10275

Figure Lengend Snippet: FIGURE 5 – Quantitative RT-PCR analysis of mdm2, p21WAF1, cyclin G1, gadd45, bax 16 hr after UVB treatment with different doses in A375P melanoma cells. Results of quantitative analysis are in Table III.

Article Snippet: Normal human melanocytes (NHM) were obtained and cultured as described previously.8 Human melanoma cell lines A375P, WM115, SK-Mel2, SK-Mel28, MeWo and Malme3M were obtained from the American Type Culture Collection.

Techniques: Quantitative RT-PCR

Cyclic mechanical strain engages the same anti-apoptotic pathway in high metastatic human melanoma as in the murine model. (A) Schematic of the experimental workflow translating the murine findings to human melanoma (B) Quantification of caspase-3/7-positive cells after 6 h of cyclic stretch. The apoptotic cell ratio was significantly reduced in the Stretch group compared to the static group in A375SM, whereas it showed a slight increase in A375P (n = 25). (C) Effect of BAX inhibition (BAI1) ± stretch. In A375SM, stretch alone lowers apoptosis more than BAI1 alone, and the combination produces an additional reduction (n = 25). (D) Effect of BCL-2 family inhibition (BH3I1) ± stretch. BH3I1 and stretch individually reduce apoptosis to a similar extent in A375SM, with no further decrease in the combined group (n = 25). (E) Effect of BAD inhibition (NPB) ± stretch. NPB and stretch each lower apoptosis in A375SM, and together yield the greatest suppression (n = 25). (F) Piezo1 inhibition (isoquercetin) raises apoptosis in A375SM irrespective of stretch, indicating a conserved mechano-protective role for Piezo1 (n = 25). (G) qPCR fold change in apoptosis-promoting genes (stretch/static). The response to these genes was blunted in A375SM compared to A375P (n = 3). (H) Fold change of anti-apoptotic genes is greater in A375SM than A375P (n = 3). (I) Fold change of proliferation markers is higher in A375SM, suggesting that caspase-3 activity may be redirected toward growth under mechanical stimulation (n = 3). ∗∗∗p < 0.0005; ∗∗p < 0.005; ∗p < 0.05, based on one-way ANOVA with Tukey HSD post-hoc testing. Error bars represent mean ± SD.

Journal: Materials Today Bio

Article Title: Cyclic mechanical stretch suppresses intrinsic apoptosis in high metastatic melanoma

doi: 10.1016/j.mtbio.2026.103132

Figure Lengend Snippet: Cyclic mechanical strain engages the same anti-apoptotic pathway in high metastatic human melanoma as in the murine model. (A) Schematic of the experimental workflow translating the murine findings to human melanoma (B) Quantification of caspase-3/7-positive cells after 6 h of cyclic stretch. The apoptotic cell ratio was significantly reduced in the Stretch group compared to the static group in A375SM, whereas it showed a slight increase in A375P (n = 25). (C) Effect of BAX inhibition (BAI1) ± stretch. In A375SM, stretch alone lowers apoptosis more than BAI1 alone, and the combination produces an additional reduction (n = 25). (D) Effect of BCL-2 family inhibition (BH3I1) ± stretch. BH3I1 and stretch individually reduce apoptosis to a similar extent in A375SM, with no further decrease in the combined group (n = 25). (E) Effect of BAD inhibition (NPB) ± stretch. NPB and stretch each lower apoptosis in A375SM, and together yield the greatest suppression (n = 25). (F) Piezo1 inhibition (isoquercetin) raises apoptosis in A375SM irrespective of stretch, indicating a conserved mechano-protective role for Piezo1 (n = 25). (G) qPCR fold change in apoptosis-promoting genes (stretch/static). The response to these genes was blunted in A375SM compared to A375P (n = 3). (H) Fold change of anti-apoptotic genes is greater in A375SM than A375P (n = 3). (I) Fold change of proliferation markers is higher in A375SM, suggesting that caspase-3 activity may be redirected toward growth under mechanical stimulation (n = 3). ∗∗∗p < 0.0005; ∗∗p < 0.005; ∗p < 0.05, based on one-way ANOVA with Tukey HSD post-hoc testing. Error bars represent mean ± SD.

Article Snippet: B16F1, B16F10, A375P, and A375SM cell lines were acquired from the Korean Cell Line Bank.

Techniques: Inhibition, Activity Assay