Journal: Vascular pharmacology

Article Title: GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na + -Ca 2+ exchanger and endoplasmic reticulum Ca 2+ refilling

doi: 10.1016/j.vph.2017.01.002

Figure Lengend Snippet: (A) Effect of 3 μM LPI on endothelial hyperpolarization to 2 μM Ach (n = 4). (B) Effect of 10 μM LPI on endothelial hyperpolarization to two consecutive administrations of 2 μM Ach (n = 3). The hyperpolarization to SKA-31 (10 μM) remained unaffected by LPI pre-exposure (n = 4). (C) Representative membrane potential recording from in situ mice aortic endothelium showing a failure of LPI (10 μM) to inhibit the hyperpolarization evoked by 10 μM SKA-31 (n = 3).

Article Snippet: LPC16:0 (1-palmitoyl-2-hydroxy- sn - glycero -3-phosphocholine) was purchased from Avanti Polar Lipids, LPI from Sigma Aldrich, paxilline and SKA-31 were purchased from Alomone Labs, KB-R7943 was purchased from TCI Chemicals.

Techniques: In Situ

Journal: International Journal of Molecular Sciences

Article Title: Bioactive Carbohydrates and Peptides in Foods: An Overview of Sources, Downstream Processing Steps and Associated Bioactivities

doi: 10.3390/ijms160922485

Figure Lengend Snippet: Bioactive peptides derived from food sources and their use as bioactives in commercial products.

Article Snippet: IPP and VPP , Antihypertensive , Ameal S 120 , Calpis Co., Ltd., Tokyo, Japan , Beverage , Milk , [ ] .

Techniques: Derivative Assay, Sequencing