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u conotoxin mviic  (Alomone Labs)
92
Alomone Labs u conotoxin mviic
Figure 3. High-Voltage-Activated Ca2+Chan- nels Mediate Most of the Extra Ca2+ Entry Caused by Nav Activation (A) Spine with scan line and TPU site. Scale bar: 2 mm. (B) Averaged uEPSP recorded at the soma of cell in (A) during control and in the presence of 1 mM u-conotoxin <t>MVIIC</t> (CTX). Scale bars: 0.5 mV, 10 ms. (C) Averaged (DF/F)TPU in spine and dendrite from (A) during control (top) and in the presence of CTX (bottom). Scale bars: 25%, 500 ms. (D) Effect of CTX on (DF/F)TPU amplitudes (n = 24 spines). Left: averaged absolute amplitudes ± SD (42% ± 17% versus 28% ± 13%, p < 0.001). Right: spine-wise amplitudes normalized to control (bold: average change ± SD to 0.67 ± 0.19). (E) Spine-wise effect of CTX on normalized uEPSP amplitudes (left, n = 20, bold: average change ± SD 1.10 ± 0.42, n.s.) and rise times (right, n = 19, average ± SD 1.08 ± 0.35, n.s.). (F) Left: TTX before CTX (n = 14). Average effect of CTX on individual amplitudes normalized to control (bold: average change ± SD to 0.88 ± 0.22 of con- trol). Right: CTX before TTX (n = 8). Average effect of TTX on individual amplitudes normalized to con- trol (bold: average change ± SD to 0.94 ± 0.26 of control).
U Conotoxin Mviic, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 92 stars, based on 1 article reviews
u conotoxin mviic - by Bioz Stars, 2026-05
92/100 stars
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Figure 3. High-Voltage-Activated Ca2+Chan- nels Mediate Most of the Extra Ca2+ Entry Caused by Nav Activation (A) Spine with scan line and TPU site. Scale bar: 2 mm. (B) Averaged uEPSP recorded at the soma of cell in (A) during control and in the presence of 1 mM u-conotoxin MVIIC (CTX). Scale bars: 0.5 mV, 10 ms. (C) Averaged (DF/F)TPU in spine and dendrite from (A) during control (top) and in the presence of CTX (bottom). Scale bars: 25%, 500 ms. (D) Effect of CTX on (DF/F)TPU amplitudes (n = 24 spines). Left: averaged absolute amplitudes ± SD (42% ± 17% versus 28% ± 13%, p < 0.001). Right: spine-wise amplitudes normalized to control (bold: average change ± SD to 0.67 ± 0.19). (E) Spine-wise effect of CTX on normalized uEPSP amplitudes (left, n = 20, bold: average change ± SD 1.10 ± 0.42, n.s.) and rise times (right, n = 19, average ± SD 1.08 ± 0.35, n.s.). (F) Left: TTX before CTX (n = 14). Average effect of CTX on individual amplitudes normalized to control (bold: average change ± SD to 0.88 ± 0.22 of con- trol). Right: CTX before TTX (n = 8). Average effect of TTX on individual amplitudes normalized to con- trol (bold: average change ± SD to 0.94 ± 0.26 of control).

Journal: Neuron

Article Title: Local postsynaptic voltage-gated sodium channel activation in dendritic spines of olfactory bulb granule cells.

doi: 10.1016/j.neuron.2014.12.051

Figure Lengend Snippet: Figure 3. High-Voltage-Activated Ca2+Chan- nels Mediate Most of the Extra Ca2+ Entry Caused by Nav Activation (A) Spine with scan line and TPU site. Scale bar: 2 mm. (B) Averaged uEPSP recorded at the soma of cell in (A) during control and in the presence of 1 mM u-conotoxin MVIIC (CTX). Scale bars: 0.5 mV, 10 ms. (C) Averaged (DF/F)TPU in spine and dendrite from (A) during control (top) and in the presence of CTX (bottom). Scale bars: 25%, 500 ms. (D) Effect of CTX on (DF/F)TPU amplitudes (n = 24 spines). Left: averaged absolute amplitudes ± SD (42% ± 17% versus 28% ± 13%, p < 0.001). Right: spine-wise amplitudes normalized to control (bold: average change ± SD to 0.67 ± 0.19). (E) Spine-wise effect of CTX on normalized uEPSP amplitudes (left, n = 20, bold: average change ± SD 1.10 ± 0.42, n.s.) and rise times (right, n = 19, average ± SD 1.08 ± 0.35, n.s.). (F) Left: TTX before CTX (n = 14). Average effect of CTX on individual amplitudes normalized to control (bold: average change ± SD to 0.88 ± 0.22 of con- trol). Right: CTX before TTX (n = 8). Average effect of TTX on individual amplitudes normalized to con- trol (bold: average change ± SD to 0.94 ± 0.26 of control).

Article Snippet: The following pharmacological agents were bath applied in some experiments: muscimol (10 mM, Tocris Bioscience), u-conotoxin MVIIC (CTX, 1 mM, Alomone), TTX (500 nM, Alomone), D-APV (25 mM, Tocris), mibefradil (10 mM, Tocris), iberiotoxin (100 nM, Tocris), 4-AP (5 mM, Tocris), and thapsigargin (10 mM, Tocris).

Techniques: Activation Assay, Control