PV-1059 Search Results


atcc pv 109  (ATCC)
92
ATCC atcc pv 109
Atcc Pv 109, supplied by ATCC, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pv1019 calbiochem  (MedChemExpress)
92
MedChemExpress pv1019 calbiochem
Pv1019 Calbiochem, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 92 stars, based on 1 article reviews
pv1019 calbiochem - by Bioz Stars, 2026-03
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chk2 inhibitors ci2  (Millipore)
90
Millipore chk2 inhibitors ci2
Chk2 Inhibitors Ci2, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pv1019  (Millipore)
90
Millipore pv1019
Pv1019, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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pv1019  (Selleck Chemicals)
95
Selleck Chemicals pv1019
Pv1019, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 95 stars, based on 1 article reviews
pv1019 - by Bioz Stars, 2026-03
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aav8 tbg cre  (Addgene inc)
96
Addgene inc aav8 tbg cre
Aav8 Tbg Cre, supplied by Addgene inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
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pv1019 (chk2 inhibitor)  (LC Laboratories)
90
LC Laboratories pv1019 (chk2 inhibitor)
Pv1019 (Chk2 Inhibitor), supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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aav8- tbg - cre  (Addgene inc)
90
Addgene inc aav8- tbg - cre
( A ) Experimental schematic for hepatocyte-specific MCP-1-knockout mice. Male 8-week-old MCP-1 fl/fl mice were transduced with <t>AAV8-</t> Tbg-Gfp (Control) or AAV8- Tbg-Cre to generate MCP-1 ΔHep male mice, then fed with NASH diet for 16 weeks ( n = 8 mice/group). ( B ) Gene expression for liver Ccl2 from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( C ) Markers of HSC activity from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( D ) Representative IHC image of Col1a1 protein expression from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice. ( E ) Liver Sirius red staining and quantitation in control and MCP-1 ΔHep male mice ( n = 8 mice/group). Scale bars: 50 μm. All data are shown with group means ± SEM; *, P < 0.05, **, P < 0.01, ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.
Aav8 Tbg Cre, supplied by Addgene inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/aav8- tbg - cre/product/Addgene inc
Average 90 stars, based on 1 article reviews
aav8- tbg - cre - by Bioz Stars, 2026-03
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pv1019  (Merck KGaA)
90
Merck KGaA pv1019
( A ) Experimental schematic for hepatocyte-specific MCP-1-knockout mice. Male 8-week-old MCP-1 fl/fl mice were transduced with <t>AAV8-</t> Tbg-Gfp (Control) or AAV8- Tbg-Cre to generate MCP-1 ΔHep male mice, then fed with NASH diet for 16 weeks ( n = 8 mice/group). ( B ) Gene expression for liver Ccl2 from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( C ) Markers of HSC activity from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( D ) Representative IHC image of Col1a1 protein expression from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice. ( E ) Liver Sirius red staining and quantitation in control and MCP-1 ΔHep male mice ( n = 8 mice/group). Scale bars: 50 μm. All data are shown with group means ± SEM; *, P < 0.05, **, P < 0.01, ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.
Pv1019, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pv1019/product/Merck KGaA
Average 90 stars, based on 1 article reviews
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pv1019 calbiochem  (Selleck Chemicals)
94
Selleck Chemicals pv1019 calbiochem
( A ) Experimental schematic for hepatocyte-specific MCP-1-knockout mice. Male 8-week-old MCP-1 fl/fl mice were transduced with <t>AAV8-</t> Tbg-Gfp (Control) or AAV8- Tbg-Cre to generate MCP-1 ΔHep male mice, then fed with NASH diet for 16 weeks ( n = 8 mice/group). ( B ) Gene expression for liver Ccl2 from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( C ) Markers of HSC activity from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( D ) Representative IHC image of Col1a1 protein expression from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice. ( E ) Liver Sirius red staining and quantitation in control and MCP-1 ΔHep male mice ( n = 8 mice/group). Scale bars: 50 μm. All data are shown with group means ± SEM; *, P < 0.05, **, P < 0.01, ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.
Pv1019 Calbiochem, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
pv1019 calbiochem - by Bioz Stars, 2026-03
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potato y potyvirus pvy  (ATCC)
90
ATCC potato y potyvirus pvy
( A ) Experimental schematic for hepatocyte-specific MCP-1-knockout mice. Male 8-week-old MCP-1 fl/fl mice were transduced with <t>AAV8-</t> Tbg-Gfp (Control) or AAV8- Tbg-Cre to generate MCP-1 ΔHep male mice, then fed with NASH diet for 16 weeks ( n = 8 mice/group). ( B ) Gene expression for liver Ccl2 from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( C ) Markers of HSC activity from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( D ) Representative IHC image of Col1a1 protein expression from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice. ( E ) Liver Sirius red staining and quantitation in control and MCP-1 ΔHep male mice ( n = 8 mice/group). Scale bars: 50 μm. All data are shown with group means ± SEM; *, P < 0.05, **, P < 0.01, ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.
Potato Y Potyvirus Pvy, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/potato y potyvirus pvy/product/ATCC
Average 90 stars, based on 1 article reviews
potato y potyvirus pvy - by Bioz Stars, 2026-03
90/100 stars
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strawberry latent ring spot nepovirus slrsv  (ATCC)
86
ATCC strawberry latent ring spot nepovirus slrsv
( A ) Experimental schematic for hepatocyte-specific MCP-1-knockout mice. Male 8-week-old MCP-1 fl/fl mice were transduced with <t>AAV8-</t> Tbg-Gfp (Control) or AAV8- Tbg-Cre to generate MCP-1 ΔHep male mice, then fed with NASH diet for 16 weeks ( n = 8 mice/group). ( B ) Gene expression for liver Ccl2 from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( C ) Markers of HSC activity from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( D ) Representative IHC image of Col1a1 protein expression from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice. ( E ) Liver Sirius red staining and quantitation in control and MCP-1 ΔHep male mice ( n = 8 mice/group). Scale bars: 50 μm. All data are shown with group means ± SEM; *, P < 0.05, **, P < 0.01, ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.
Strawberry Latent Ring Spot Nepovirus Slrsv, supplied by ATCC, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/strawberry latent ring spot nepovirus slrsv/product/ATCC
Average 86 stars, based on 1 article reviews
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Image Search Results


( A ) Experimental schematic for hepatocyte-specific MCP-1-knockout mice. Male 8-week-old MCP-1 fl/fl mice were transduced with AAV8- Tbg-Gfp (Control) or AAV8- Tbg-Cre to generate MCP-1 ΔHep male mice, then fed with NASH diet for 16 weeks ( n = 8 mice/group). ( B ) Gene expression for liver Ccl2 from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( C ) Markers of HSC activity from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( D ) Representative IHC image of Col1a1 protein expression from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice. ( E ) Liver Sirius red staining and quantitation in control and MCP-1 ΔHep male mice ( n = 8 mice/group). Scale bars: 50 μm. All data are shown with group means ± SEM; *, P < 0.05, **, P < 0.01, ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.

Journal: JCI Insight

Article Title: Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis

doi: 10.1172/jci.insight.165369

Figure Lengend Snippet: ( A ) Experimental schematic for hepatocyte-specific MCP-1-knockout mice. Male 8-week-old MCP-1 fl/fl mice were transduced with AAV8- Tbg-Gfp (Control) or AAV8- Tbg-Cre to generate MCP-1 ΔHep male mice, then fed with NASH diet for 16 weeks ( n = 8 mice/group). ( B ) Gene expression for liver Ccl2 from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( C ) Markers of HSC activity from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice ( n = 8 mice/group). ( D ) Representative IHC image of Col1a1 protein expression from chow- or NASH diet–fed control mice or MCP-1 ΔHep male mice. ( E ) Liver Sirius red staining and quantitation in control and MCP-1 ΔHep male mice ( n = 8 mice/group). Scale bars: 50 μm. All data are shown with group means ± SEM; *, P < 0.05, **, P < 0.01, ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.

Article Snippet: We transduced 8- to 10-week-old mice carrying floxed alleles with 1.5 × 10 11 genome copies of AAV8- Tbg - Cre (Addgene plasmid AV-8-PV109) or AAV8- Tbg - Gfp (Addgene plasmid AV-8-PV0146) by tail vein injection.

Techniques: Knock-Out, Transduction, Control, Gene Expression, Activity Assay, Expressing, Staining, Quantitation Assay

( A ) Chow-fed NICD fl/fl and NICD fl/fl MCP-1 fl/fl were transduced with AAV8- Tbg-Gfp or AAV8- Tbg-Cre to generate control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 8 mice/group). ( B ) Liver Ccl2 and Notch target gene expression and ( C ) serum MCP-1 levels in control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 8 mice/group). ( D ) FACS analysis of nonparenchymal cells (NPCs) isolated from livers of control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 4 mice/group). ( E ) Gene expression for markers of HSC activity from livers of control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 8 mice/group). ( F ) Representative IHC image of Col1a1 protein expression from livers of control, L-NICD , and L-NICD MCP-1 ΔHep male mice. ( G ) Hydroxyproline content from livers of control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 8 mice/group). ( H ) Liver Sirius red staining and quantitation in control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 8 mice/group). Scale bar: 50 μm. All data are shown with group means ± SEM; *, P < 0.05, **, P < 0.01, ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.

Journal: JCI Insight

Article Title: Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis

doi: 10.1172/jci.insight.165369

Figure Lengend Snippet: ( A ) Chow-fed NICD fl/fl and NICD fl/fl MCP-1 fl/fl were transduced with AAV8- Tbg-Gfp or AAV8- Tbg-Cre to generate control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 8 mice/group). ( B ) Liver Ccl2 and Notch target gene expression and ( C ) serum MCP-1 levels in control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 8 mice/group). ( D ) FACS analysis of nonparenchymal cells (NPCs) isolated from livers of control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 4 mice/group). ( E ) Gene expression for markers of HSC activity from livers of control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 8 mice/group). ( F ) Representative IHC image of Col1a1 protein expression from livers of control, L-NICD , and L-NICD MCP-1 ΔHep male mice. ( G ) Hydroxyproline content from livers of control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 8 mice/group). ( H ) Liver Sirius red staining and quantitation in control, L-NICD , and L-NICD MCP-1 ΔHep male mice ( n = 8 mice/group). Scale bar: 50 μm. All data are shown with group means ± SEM; *, P < 0.05, **, P < 0.01, ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.

Article Snippet: We transduced 8- to 10-week-old mice carrying floxed alleles with 1.5 × 10 11 genome copies of AAV8- Tbg - Cre (Addgene plasmid AV-8-PV109) or AAV8- Tbg - Gfp (Addgene plasmid AV-8-PV0146) by tail vein injection.

Techniques: Transduction, Control, Targeted Gene Expression, Isolation, Gene Expression, Activity Assay, Expressing, Staining, Quantitation Assay

( A ) Chow-fed NICD fl/fl male mice were transduced with AAV8- Tbg-Gfp or AAV8- Tbg-Cre to generate control and L-NICD mice, then treated with vehicle or CCR2i (30 mg/kg/d) by daily oral gavage for 2 weeks ( n = 8 mice/group). ( B ) FACS analysis of CD11b + Ly6C + and ( C ) F4/80 + nonparenchymal cells (NPCs) isolated from livers of control and L-NICD male mice treated with CCR2i or vehicle ( n = 4–5 mice/group). ( D ) Gene expression for markers of HSC activity in control and L-NICD male mice treated with CCR2i or vehicle ( n = 8 mice/group). ( E ) Representative IHC image of Col1a1 protein expression in control and L-NICD male mice treated with CCR2i or vehicle. ( F ) Hydroxyproline content in control and L-NICD male mice treated with CCR2i or vehicle ( n = 8 mice/group). ( G ) Liver Sirius red staining and quantitation in control and L-NICD male mice treated with CCR2i or vehicle ( n = 8 mice/group). Scale bar: 50 μm. All data are shown with group means ± SEM; *, P < 0.05; **, P < 0.01; ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.

Journal: JCI Insight

Article Title: Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis

doi: 10.1172/jci.insight.165369

Figure Lengend Snippet: ( A ) Chow-fed NICD fl/fl male mice were transduced with AAV8- Tbg-Gfp or AAV8- Tbg-Cre to generate control and L-NICD mice, then treated with vehicle or CCR2i (30 mg/kg/d) by daily oral gavage for 2 weeks ( n = 8 mice/group). ( B ) FACS analysis of CD11b + Ly6C + and ( C ) F4/80 + nonparenchymal cells (NPCs) isolated from livers of control and L-NICD male mice treated with CCR2i or vehicle ( n = 4–5 mice/group). ( D ) Gene expression for markers of HSC activity in control and L-NICD male mice treated with CCR2i or vehicle ( n = 8 mice/group). ( E ) Representative IHC image of Col1a1 protein expression in control and L-NICD male mice treated with CCR2i or vehicle. ( F ) Hydroxyproline content in control and L-NICD male mice treated with CCR2i or vehicle ( n = 8 mice/group). ( G ) Liver Sirius red staining and quantitation in control and L-NICD male mice treated with CCR2i or vehicle ( n = 8 mice/group). Scale bar: 50 μm. All data are shown with group means ± SEM; *, P < 0.05; **, P < 0.01; ***, P < 0.001 by 1-way ANOVA followed by Tukey’s multiple comparisons test.

Article Snippet: We transduced 8- to 10-week-old mice carrying floxed alleles with 1.5 × 10 11 genome copies of AAV8- Tbg - Cre (Addgene plasmid AV-8-PV109) or AAV8- Tbg - Gfp (Addgene plasmid AV-8-PV0146) by tail vein injection.

Techniques: Transduction, Control, Isolation, Gene Expression, Activity Assay, Expressing, Staining, Quantitation Assay